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  • Fusarium: Molecular Diversi...
    Al-Hatmi, Abdullah M S; Meis, Jacques F; de Hoog, G Sybren

    PLOS pathogens, 04/2016, Volume: 12, Issue: 4
    Journal Article

    After 1960, the increasing use of antibiotics became a major predisposing condition 4. Since 1970, prolonged neutropenia due to intensified cytotoxic treatment of hematologic malignancies was the leading risk factor in novel types of fusariosis 5. Since 1980, Fusarium infections have been seen in severely immunocompromised patients with a 100% mortality rate, e.g., in cases of cerebral involvement 6. To date, about 36 of the alleged human opportunists carry a name, while 38 are still unnamed and can only be identified by multilocus sequence analysis (MLSA). ...far, 21 species have been described with proven case reports 16, and more have been published in the literature.