The patient was a 15-year-old woman who had a history of operation of cavernous hemangioma at her left knee at the age of 2. She had hemangiomas of the skin, ion-defficiency anemia, and also gastric and colonic hemangiomas detected by the examination of the alimen-tary tract, which leads to the diagnosis of blue rubber bleb nevus syndrome. Endoscopic mucosal resection, local injection of ethanol, etc. were carried out against the hemangiomas of stomach and colon. We have followed her up successfully through the endoscopic treatment of the newly developed hemangimas of stomach and colon without laparotomy during subsequent ten years. We proved in this case that the endoscopic treatment of the alimentary tract hemangiomas showing blue rubber bleb nevus syndrome was safe and useful.