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Nevrofiziološka opredelitev delovanja perifernega živčevja pri maničnodperesivnih bolnikih, zdravljenih z litijem = Neurophysiological assessment of peripheral nervous system function in manic-depressive patients, treated with lithiumPodnar, SimonInfluence of lithium on peripheral nervous function was evaluated by comparingmeasurements of neurophysiological parameters in two groups of patients and a group of healthy volunteers. There were 20 ... lithium treated manic-depressive patients in the first group, 20 affective-psychotic patients without the lithium treatment in the second and 20 age and height matched healthy volunteers in the third. Motor system function was neurophysiologically assessed by measuring M wave amplitude after proximal anddistal stimulation of the median and peroneal nerves, by calculating conduction velocity and by F wave latencies. Sensory system function of the median and sural nerves was assessed by measuring sensory conduction velocity and neurogram duration and amplitude. We found lower amplitudes of M waves on median neuve stimulation in both groups of patients (p < 0.015)č M wave amplitudes on peroneal nerve stimulation were lower only in the group of lithium treated manic-depressive patients (p c 0.055). In sensory system only on median nerve stimulation amplitudes of neurograms were lower in both groupsof patients comparing to healthy volunteers (p < 0.020). Our results show light pathological affection of motor and sensory axons in affective-psychotic patients, which is only a bit more severe in the lithium treated patients. This subclinical affection of peripheral nerves in manic-depressive patients is most likely due to several reasons, lithium (within therapeutic plasma concentrations) being just one.Vrsta gradiva - raziskovalno poročilo ; neleposlovje za odrasleZaložništvo in izdelava - Ljubljana : [S. Podnar], 1992Jezik - slovenskiCOBISS.SI-ID - 3016212
Avtor
Podnar, Simon
Drugi avtorji
Vodušek, David B. |
Žvan, Vukosav
Teme
Bipolar disorders |
Therapy |
Lithium |
Adverse effects |
Peripheral nerves |
Physiopathology |
Peripheral nerves |
Drug effects |
Nevral conduction |
Bipolarne motnje |
Terapija |
Litij |
Škodljivi učinki |
Periferni živci |
Patofiziologija |
Periferni živci |
Učinki zdravil |
Prevajanje po živcu |
nevrologija
Knjižnica/institucija |
Kraj | Akronim | Za izposojo | Druga zaloga |
---|---|---|---|---|
MF, Centralna medicinska knjižnica, Ljubljana | Ljubljana | CMK |
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Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Podnar, Simon | 14502 |
Vodušek, David B. | 07476 |
Žvan, Vukosav | 07179 |
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