-
Birth seasonality of childhood central nervous system tumors : analysis of primary data from 16 Southern-Eastern European population-based registriesKaralexi, Maria A. ...Season of birth, a surrogate of seasonal variation of environmental exposures, has been associated with increased risk of several cancers. In the context of a Southern-Eastern Europe (SEE) ... consortium, we explored the potential association of birth seasonality with childhood (0-14 years) central nervous system (CNS) tumors. Primary CNS tumor cases (n=6014) were retrieved from 16 population-based SEE registries (1983- 2015). Poisson regression and meta-analyses on birth season were performed in nine countries with available live birth data (n=4987). Sub-analyses by birth month, age, gender and principal histology were also conducted. Children born during winter were at a slightly increased risk of developing a CNS tumor overall [incidence rate ratio (IRR): 1.06, 95% confidence intervals (CI): 0.99-1.14], and of embryonal histology specifically (IRR: 1.13, 95% CI: 1.01-1.27). The winter peak of embryonal tumors was higher among boys (IRR: 1.24, 95% CI: 1.05-1.46), especially during the first four years of life (IRR: 1.33, 95% CI: 1.03-1.71). By contrast, boys <5 years born during summer seemed to be at a lower risk of embryonal tumors (IRR: 0.73, 95% CI: 0.54-0.99). A clustering of astrocytomas was also found among girls (0-14 years) born during spring (IRR: 1.23, 95% CI: 1.03-1.46). Although, the present exploratory results are by no means definitive, they provide some indications for age-, gender- and histology-related seasonal variations of CNS tumors. Expansion of registration and linkage with cytogenetic reports could refine if birth seasonality is causally associated with CNS tumors and shed light into the complex pathophysiology of this lethal disease.Vir: International journal of cancer = Journal international du cancer. - ISSN 0020-7136 (Vol. 147, no. 5, 2020, str. 1252-1263)Vrsta gradiva - članek, sestavni delLeto - 2020Jezik - angleškiCOBISS.SI-ID - 3447163
Avtor
Karalexi, Maria A. |
Dessypris, Nick |
Georgakis, Marios K. |
Ryzhov, Anton |
Jakab, Zsuzsanna |
Zborovskaya, Anna A. |
Dimitrova, Nadya |
Živković, Snežana, zdravnica |
Trojanowski, Maciej |
Žagar, Tina, 1979-
Teme
rak centralnega živčnega sistema |
otroštvo |
epigenetika |
register raka |
central nervous system tumors |
childhood |
epigenetics |
cancer registry
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|---|
Karalexi, Maria A. | |
Dessypris, Nick | |
Georgakis, Marios K. | |
Ryzhov, Anton | |
Jakab, Zsuzsanna | |
Zborovskaya, Anna A. | |
Dimitrova, Nadya | |
Živković, Snežana, zdravnica | |
Trojanowski, Maciej | |
Žagar, Tina, 1979- | 25531 |
Izberite prevzemno mesto:
Prevzem gradiva po pošti
Obvestilo
Gesla v Splošnem geslovniku COBISS
Izbira mesta prevzema
Mesto prevzema | Status gradiva | Rezervacija |
---|
Prosimo, počakajte trenutek.