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Influenza A, Influenza B, human respiratory syncytial virus and SARSCoV-2 molecular diagnostics and epidemiology in the post COVID-19 era [Elektronski vir]Luštrek, Manca, biologinja in mikrobiologinja ...Background: The concurrent circulation of SARS-CoV-2 with other respiratory viruses is unstoppable and represents a new diagnostic reality for clinicians and clinical microbiology laboratories. ... Multiplexed molecular testing on automated platforms that focus on the simultaneous detection of multiple respiratory viruses in a single tube is a useful approach for current and future diagnosis of respiratory infections in the clinical setting. Methods: Two time periods were included in the study: from February to April 2022, an early 2022 period, during the gradual lifting of COVID-19 prevention measures in the country, and from October 2022 to April 2023, the 2022/23 respiratory infections season. We analysed a total of 1,918 samples in the first period and 18,131 respiratory samples in the second period using a multiplex molecular assay for the simultaneous detection of Influenza A (Flu-A), Influenza B (Flu-B), Human Respiratory Syncytial Virus (HRSV) and SARS-CoV-2. Results: The results from early 2022 showed a strong dominance of SARS-CoV-2 infections with 1,267/1,918 (66.1%) cases. Flu-A was detected in 30/1,918 (1.6%) samples, HRSV in 14/1,918 (0.7%) samples, and Flu-B in 2/1,918 (0.1%) samples. Flu-A/SARS-CoV-2 co-detections were observed in 11/1,267 (0.9%) samples, and HRSV/SARS-CoV-2 co-detection in 5/1,267 (0.4%) samples. During the 2022/23 winter respiratory season, SARS-CoV-2 was detected in 1,738/18,131 (9.6%), Flu-A in 628/18,131 (3.5%), Flu-B in 106/18,131 (0.6%), and HRSV in 505/18,131 (2.8%) samples. Interestingly, co-detections were present to a similar extent as in early 2022. Conclusion: The results show that the multiplex molecular approach is a valuable tool for the simultaneous laboratory diagnosis of SARS-CoV-2, Flu-A/B, and HRSV in hospitalized and outpatients. Infections with Flu-A/B, and HRSV occurred shortly after the COVID-19 control measures were lifted, so a strong reoccurrence of various respiratory infections and co-detections in the post COVID-19 period was to be expected.Vir: Respiratory research [Elektronski vir]. - ISSN 1465-993X (Vol. 25, iss. 1, [article no.] 234, 2024, str.1-9)Vrsta gradiva - e-članekLeto - 2024Jezik - angleškiCOBISS.SI-ID - 199445507
Avtor
Luštrek, Manca, biologinja in mikrobiologinja |
Prestor, Zala |
Suljič, Alen |
Kogoj, Rok |
Knap, Nataša, 1978- |
Jevšnik Virant, Monika |
Uršič, Tina, 1980- |
Petrovec, Miroslav |
Avšič-Županc, Tatjana |
Korva, Miša
Teme
co-detections |
Flu-A/B |
HRSV |
multiplex |
SARS-CoV-2 |
turnaround-time |
rtRT-PCR |
soodkrivanje |
Flu-A/B |
HRSV |
multipleks |
SARS-CoV-2 |
čas obrabe |
rtRT-PCR
Vnos na polico
Trajna povezava
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Faktor vpliva
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Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Luštrek, Manca, biologinja in mikrobiologinja | |
Prestor, Zala | |
Suljič, Alen | 52539 |
Kogoj, Rok | 29937 |
Knap, Nataša, 1978- | 28601 |
Jevšnik Virant, Monika | 29997 |
Uršič, Tina, 1980- | 25433 |
Petrovec, Miroslav | 15902 |
Avšič-Županc, Tatjana | 10331 |
Korva, Miša | 30696 |
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26.7., 15.8. in 16.8. 2024 bo knjižnica ZAPRTA.