Centralna tehniška knjižnica Univerze v Ljubljani (CTK)
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Probiotics in health and disease : distinct roles of different strains in natural killer cell activation and regulationKaur, Kawaljit ...Elucidating the role of probiotic bacteria in health and disease perhaps constitutes one of the most exciting and fastest growing fields in medicine as we uncover the beneficial roles of these ... bacteria in many disease processes including cancer. We and others have reported previously that probiotic bacteria play a significant role in the activation of many cells including the cancer fighting natural killer (NK) cells. NK cells are the key immune effectors which control tumor growth and metastasis due to their ability to mediate direct cytotoxicity and/or differentiation of cancer stem cells/undifferentiated tumors through secreted and membrane bound interferon-gamma and tumor necrosis factor-alpha. In this review, we present an overview of recent studies from our laboratory and those of the others on their beneficial effects on immune cell function in particular on NK cells. In addition, we also highlight the current understanding of the role of probiotics in enhancement of the effectiveness of cancer therapeutics. Moreover, we discuss the functional impairment of cancer patients' NK cells and the role of probiotics in reversal of such functional impairment. NK cell-based immuno-therapies in combination with well-selected strains of probiotic bacteria may probably represent one of the best adjunct therapeutic approaches to prevent and treat cancer in the future.Vir: Critical reviews in immunology. - ISSN 1040-8401 (Vol. 41, iss. 2, 2021, str. 1-19)Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasleLeto - 2021Jezik - angleškiCOBISS.SI-ID - 61314819
Avtor
Kaur, Kawaljit |
Ko, Meng-Wei |
Jewett, Anahid |
Chen, Po-Chun |
Breznik, Barbara, 1989- |
Senjor, Emanuela |
Wong, Paul |
Wang, Yuhao |
Chovatiya, Nishant
Teme
NK cells |
cancer stem cells |
differentiation |
cancer immunotherapy |
probiotics |
imunotoksičnost |
matične celice raka |
probiotiki
Vnos na polico
Trajna povezava
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Kaur, Kawaljit | |
Ko, Meng-Wei | |
Jewett, Anahid | |
Chen, Po-Chun | |
Breznik, Barbara, 1989- | 36319 |
Senjor, Emanuela | 51713 |
Wong, Paul | |
Wang, Yuhao | |
Chovatiya, Nishant |
Vir: Osebne bibliografije
in: SICRIS
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