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Fakulteta za farmacijo, Ljubljana (FFALJ)
  • Practical assessment of the suitability of IQC control materials in haemocytometry based on biologic goals
    Skitek, Milan
    We have assessed short and long-term imprecision goals based on biological variation in haemocytometry through internal quality control (IQC) for the following parametersČ white blood cell (WBC), red ... blood cell (RBC) and platelet (Plt) counts, concentration of haemoglobin (Hb) and mean cell volume (MCV). The attainment of short-term imprecision goals in the IQC system with our own and commercial control blood (between-day control) presents problem for MCV, where minimum performance is achievable, the analytical coefficient of variation (CV) being less than three-quarter of the average within-subject variation (CV I), i.e. CV<0.75 CV I. For the other four parameters desirable performance (CV<0.50 CV I) and even optimum performance-CV<0.25 CV I (for WBC and Hb) is achievable. The long-term desirable imprecision goals (CV L) based on within- and between-subject variation (CV G) seem to be too loose. However optimum performance is attainable for all five basic haemocytometry parameters. In the IQC system with retained patient specimens (within-day control), short-term imprecision goals for optimum performance are surpassed for WBC and Hb and desirable performance is achieved for RBC, MCV and Plt.
    Vir: Accreditation and quality assurance : journal for quality, comparability and reliability in chemical measurement. - ISSN 0949-1775 (Vol. 8, no. 11, 2003, str. 514-519)
    Vrsta gradiva - članek, sestavni del
    Leto - 2003
    Jezik - angleški
    COBISS.SI-ID - 1400945

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