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Kronični potek alergijskih bolezni = Chronicity of the allergic diseasePorenta-Bešić, Vlasta ; Kuhar, MarijanaChronic type of allergic tissue reactions is a combination of type I and type IV a2 hypersensitivity responses. Antigen induces release of performed (the principle mediator is histamine) and newly ... formed mediators by mast cells. These reactions occur within minutes and have a prolonged effect within several hours. Mastocyts may also contribute to chronic allergic reactions by releasing cytokins. Antigen is presented to Th2 type helper lymphocytes by antigen presenting cells. Th2 cells release interleukin-4, which is an essential cofactor for IgE synthesis by B cells. Th2 cells also release other mediators which are referred to as eosinophil-activating cytokines. Eosinophils themselves synthetise, store and secrete several cytokines. They are influenced by cell adhesion molecules. Eosinophil recruitment may result from local release of chemokines and cytokines. Activated eosinophils are believed to cause allergic tissue damage through the release of basic proteinsfrom the crystalloid granule as well as from membrane-derived lipids such as leukotriens.Vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 38, supl. 7, nov. 1999, str. 131-137)Vrsta gradiva - članek, sestavni delLeto - 1999Jezik - slovenskiCOBISS.SI-ID - 10936281
Avtor
Porenta-Bešić, Vlasta |
Kuhar, Marijana
Teme
Hypersensitivity, immediate |
Diagnosis |
Therapy |
Etiology |
Hypersensitivity, delayed |
Therapy |
Etiology |
Diagnosis |
Mast cells |
Eosinophils |
Chemotaxis, leukocyte |
Glucocorticoids |
alergijske bolezni |
alergijske reakcije |
vnetja |
preobčutljivost |
zdravljenje
Vnos na polico
Trajna povezava
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Kuhar, Marijana | 03572 |
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