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  • Ocena prehranskega stanja bolnikov s karcinomom glave in vratu, zdravljenih z radiokemoterapijo = Assessment of nutritional status of the head and neck carcinoma patients treated with radiochemotherapy
    Strojan, Primož ; Stegel, Petra ; Rotovnik-Kozjek, Nada
    Background. Due to its localization in the oral cavity, pharynx or larynx, thehead and neck carcinoma affects, already in early disease stages, normal nutrition of patients. In Slovenia, systematic ... nutritional evaluation has not been so far included into the every day management of these patients. The aim of this study was to assess the nutritional status of the head and neck carcinoma patients before and after therapy with chemoradiation and to determine its influence on the treatment course. Methods. Prospectively, 30 patients (29 males, 1 female) with squamous cell carcinoma of the head and neck, aged between 38 and 81 years (mean 58 years), entered the study. They were all treated with curative intent. The protocol for nutritional status evaluation consisted of an internationally recognized but nonspecific scoring questionnaire Mini Nutritional Assessment (MNA) test, containing questions regarding the disease and nutritional habits of a patient, anthropometric measurements, and analysis of some laboratory parameters (lymphocyte count, serum concentrations of total proteins, al bumins and transferin). Results. Before therapy, 33% of patients were classified as normally nourished, whereasafter the therapy, the percentage was only 3% (P = 0. 006). Median weight loss during the therapy was 6.8` of the initial body weight (range: -16.2 to +3.1%); statistically significant weight loss was recorded after the second week of the therapy (P < 0.0001). The differences of body mass index and of all four laboratory parameters measured before and after the therapy were also statistically significant (P < 0.05). Therapy was temporarily interrupted in five (17%) patients, and no correlation was observed with any of the parameters used for nutritional status evaluation. (Abstract truncated at 2000 characters).
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 4, apr. 2005, str. 233-238)
    Vrsta gradiva - članek, sestavni del
    Leto - 2005
    Jezik - slovenski
    COBISS.SI-ID - 19254489

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