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  • Priporočila za uporabo biokemijskih označevalcev pri srčnem popuščanju = Recommendations on the use of biochemical markers in heart failure
    Osredkar, Joško, 1955-
    The heart must be viewed as both a biological pump that cycles approximately 100,000 times per day and as an important hormone producing organ that produces biochemical signals that are antagonists ... for the sympathetic nervous system and the renin-angiotensin-aldosterone axis . Physiologically, there area number of structurally and functionally related "heart hormones" manufactured by human cardiocytes. These include atrial natriuretic peptide (ANP), brain (or B-type) natriuretic peptide (BNP) and their respective N-terminal (NT) metabolic peptides termed NTANP and NT-proBNP. Release of the natriuretic peptides is stimulated by hemodynamic stress; these hormones have powerful diuretic, natriuretic, and vascular smooth muscle relaxing actions. Because of their central pathophysiological role in the cardiovascular system,the natriuretic peptides are elevated in conditions characterized by wall stretch, ventricular dilation and/or increased pressures resulting from excess fluid retention. Activation of the natriuretic system functions to reduce fluid blood volume and blood pressure.
    Vir: Slovenska kardiologija : znanstveno strokovna revija za področje srčno-žilne medicine. - ISSN 1581-8543 (Letn. 4, št. 2, 2007, str. 120-126)
    Vrsta gradiva - članek, sestavni del
    Leto - 2007
    Jezik - slovenski
    COBISS.SI-ID - 23496665

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