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  • Molekularni mehanizmi, vpleteni v razvoj raka želodca = Molecular mechanisms of gastric cancer development
    Hudler, Petra, 1976-
    Background: Owing to uncharacteristic symptoms, glandular stomach cancer (adenocarcinoma) is usually diagnosed at an advanced stage, when the prognosisis poor. Research showed that these tumours are ... very heterogeneous interms of their molecular structure. Gastric cancer is believed to result from a multistep process encompassing different genomic, genetic and epigenetic changes. It is widely acknowledged that its development is the result of an interplay between genetic background of patients, accumulation ofalterations in genes, and environmental risk factors. Studies, conducted over the last few decades, revealed numerous mutated genes, which could be associated with the risk of gastric cancer development. Unfortunately, the pathways and molecular sequences underlying the initiation and progression of normal cells into malignant ones have not been clearly explained yet. The purpose of this review is to present molecular mechanisms most likely implicated in gastric cancer development.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 81, št. 1, jan. 2012, str. 54-60)
    Vrsta gradiva - članek, sestavni del
    Leto - 2012
    Jezik - slovenski
    COBISS.SI-ID - 29488089

    Povezava(-e):

    http://www.szd.si/user_files/vsebina/Zdravniski_Vestnik/2012/januar/54-60.pdf
    Digitalna knjižnica Slovenije - dLib.si

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