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  • Kronična okužba in razvoj ateroskleroze s poudarkom na pomenu okužbe s klamidijo = Cronic infection and the development of atherosclerosis with emphasis on the role of chlamydial infection
    Fras, Zlatko
    Atherosclerosis is a complex disease. The concept of its association with inflammation is not new - in the last decade new evidence has emerged on direct and indirect mechanisms by which various ... chronic infections play a rolein the initiation and/or progression of atherosclerosis. The article reviews the available epidemiological and pathological data as well as a few possible mechanisms of the pathogenetic associations (the most frequently reported are infections with Helicobacter pylori, Chlamydia pneumoniae and cytomegalovirus). The association of atherosclerosis with a persistent state of chlamydial infection is well documented, although its causal role remains uncertain. Large prospective trials of antibiotics active against C. pneumoniae in the secondary prevention of coronary heart disease are being designed. The possible role of acute infections and inflammation causing prolonged endothelial dysfunction (endothelial 'stunning') is also discussed briefly.
    Vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 37, supl. 3, apr. 1998, str. 55-68)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 7887065

vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 37, supl. 3, apr. 1998, str. 55-68)

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