The VHMPID RICH upgrade project for ALICE at LHC Di Mauro, A.; Agocs, A.; Alfaro, R. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
05/2011, Letnik:
639, Številka:
1
Journal Article
Recenzirano
RHIC results have shown the importance of high momentum particles as hard probes and the need for particle identification (PID) in a very large momentum range. A Very High Momentum PID (VHMPID) ...detector has been proposed as upgrade of ALICE to extend the track-by-track identification capabilities for charged hadrons from the present 5
GeV/c limit to the momentum range 10–30
GeV/c. The VHMPID detector is a focusing RICH using C
4F
10 gaseous radiator coupled to a CsI-based photon detector. Detector design studies, achievable Cherenkov angle resolution, expected performance and high momentum triggering will be discussed.
.
The Extreme Energy Events Project is an experiment for the detection of Extensive Air Showers which exploits the Multigap Resistive Plate Chamber technology. At the moment 40 EEE muon telescopes, ...distributed all over the Italian territory, are taking data, allowing the relative analysis to produce the first interesting results, which are reported here. Moreover, this Project has a strong added value thanks to its effectiveness in terms of scientific communication, which derives from the peculiar way it was planned and carried on.
Very high momentum particle identification in ALICE at the LHC Agocs, A.; Alfaro, R.; Barnafoldi, G.G. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
05/2010, Letnik:
617, Številka:
1
Journal Article
Recenzirano
We propose to construct and install a limited acceptance detector to identify hadrons (pions, K, p) up to 30
GeV/
c on a track-by-track basis in space available in ALICE. Details and PID performance ...simulation results will be presented for two possible options, including a high transverse momentum (
p
T
) trigger for this detector. The first option is a RICH design with a
C
4
F
10
gas UV-photon radiator, UV-mirror, quartz window and pad-readout. This design requires additional tracking detectors to enable high
p
T
triggering. A second option is a combination of three detectors: a RICH with
CF
4
gas both as a UV-photon radiator and as a gas amplification medium (a windowless approach); and a threshold Cherenkov detector (
C
4
F
10
) with a quartz window and pad readout. The response for minimum ionizing particles (MIP) and UV-photons in these detectors can be well separated. With an additional tracking detector this design will also provide high
p
T
triggering. The simulation includes UV-photon production due to
CF
4
scintillation.
.
Time correlated events due to cosmic muons from extensive air showers have been detected by means of telescope pairs of the EEE (Extreme Energy Events) Project array. The coincidence rate, properly ...normalized for detector acceptance, efficiency and altitude location, has been extracted as a function of the relative distance between the telescopes. The results have been also compared with additional measurements carried out by small scintillator detectors at various distances.
Algal mass productions are widespread events throughout the world. Most research deals with the environmental impact, ecology and toxicity of these phenomena, but the algae are also promising sources ...of bioactive natural products, and also are potential food additives. In the current study, we aimed to characterize the carotenoid composition of three non-toxic algal isolates with distinct taxonomical position, namely Dunaliella salina, Euglena sanguinea and a Nostoc strain.
The strains were screened for carotenoid composition with HPLC–UV–APCI-MS with comparison with authentic standards. Carotenoids were purified with open column chromatography, and characterized by LC–UV–MS and NMR.
All three species contained a high amount of carotenoids. The composition of the carotenoid pattern was somewhat different compared to literature data. The Dunaliella carotenoid fraction contained lutein (52.1% of total carotenoid), β-carotene (13.1%), violaxanthin (11.5%) and neoxanthin (6.2%) as chief compounds. The chief carotenoids in the Nostoc strain was echinenone (34.9%), while the main components of the Euglena isolate were diatoxanthin (39.0%), lutein (23.7%), an unidentified carotenoid (9.6%) and β-carotene (5.4%). Diatoxanthin is identified by NMR spectroscopy.
The carotenoid patterns of the examined strains are somewhat different from the patterns described in the literature. This can be the results of genetic or environmental differences, or combinations thereof. Despite these differences, our study shows the potency of these algae in production of carotenoids, and possibly, usage as food additives.
•Characterization of the carotenoids of a lutein-rich Dunaliella salina strain•Characterization of the carotenoids of an echinenone-rich Nostoc strain•Characterization of the carotenoids of a diatoxanthin-rich Euglena sanguinea strain•Three non-toxic algae were shown to be excellent natural sources of carotenoids.
Patents and publications provide information on the relationships between players in different technologies, and can give a picture on the maturity and development of the technologies. This ...information can be visualized in sociograms where organisations are represented by nodes and edges signify collaborations between them. Such sociograms are useful for analysing players and collaborations within technology fields, and how these evolve over time. The patent and publication documents needed to create these sociograms can be acquired from various sources; however, the dataset needed can be huge, thus making it difficult and time-consuming to collect and present the data in an intuitive manner. This paper discusses how a set of software tools can be used to gather and visualize this data, to gain understanding of different technology landscapes, and provide a means to perform a deeper analysis of the organisations involved and the technologies themselves. Furthermore, a novel way to access these sociograms is proposed, by navigating through higher-level sociograms of interconnected technologies, where connections between those technologies signify co-occurrences of them in papers and/or patents. This is an improvement to traditional navigating through menus or lists, which tend to become confusing and overwhelming, when the amount of information is vast and hard to categorize unequivocally.
The Extreme Energy Events Project (EEE Project) is an innovative experiment to study very high energy cosmic rays by means of the detection of the associated air shower muon component. It consists of ...a network of tracking detectors installed inside Italian High Schools. Each tracking detector, called EEE telescope, is composed of three Multigap Resistive Plate Chambers (MRPCs). At present, 43 telescopes are installed and taking data, opening the way for the detection of far away coincidences over a total area of about 3 × 10
5
km
2
. In this paper we present the Monte Carlo simulations that have been performed to predict the expected coincidence rate between distant EEE telescopes.
Compound lipophilicity connected to ADME(T)(a) has great importance in drug development and it has to be evaluated by the generally used drug developmental process. In addition to the importance of ...lipophilicity in ADMET, recently it has been reported that lipophilicity of small molecules correlates with their antiproliferative activity because of certain specific hydrophobic and lipophilic interactions. Due to the complexity of ADME(T) parameters an efficient and fast method is needed to characterize the many promising candidate lead molecules as a preselection in order not to be rejected from the latter phase of drug development. In the present paper we provide an overview of the importance of lipophilicity of drug candidates for biological action and for ADME(T) and describe a novel approach for drug-likeness characterization of a molecular library using correlation study between lipophilicity and biological activity. Lipophilicity and molecular characteristics have been measured, predicted and optimized for a diverse library from which the best members have been selected to describe their biological, chemical and drug-likeness properties. Molecules were selected from the family of alpha,beta-unsaturated ketones and thorough HPLC characterization for lipophilicity and morphological, antiproliferative and flow cytometric studies were carried out on them. Based on the results 17 member isochromanone library including E and Z geometric isomers were selected for further characterization. In this focused library linear correlation has been found between the calculated and measured lipophilicity and significant parabolic correlation was found between the antiproliferative effect and lipophilicity. Using our efficient and fast method, from a diverse library, we identified an outstandingly effective inhibitor of A431 tumour cell growth via a PARP(a) cleavage dependent apoptosis. In summary the optimized HPLC analyses of lipophilicity combined with the cell-culture assay, introduced above, resulted in the determination of an optimal lipophilicity range. This optimized lipophilicity range should be used in designing novel antiproliferative compounds.
Jets and Underlying Events at LHC Energies Agocs, A G; Barnafoldi, G G; Levai, P
Journal of physics. Conference series,
01/2011, Letnik:
270, Številka:
1
Journal Article
Recenzirano
Odprti dostop
Jet-matter interaction remains a central question and a theoretical challenge in heavy-ion physics and might become important in high-multiplicity events in proton-proton collisions at LHC energies. ...Full jet measurement at LHC offer the proper tool to investigate energy loss process and fragmentation of hard parton in the medium. Since jet reconstruction will be constrained to small cone sizes, then study of the connection between jets and surrounding environment provides a further possibility to extend our exploration. We study jets at 14 TeV and pp collisions at 7 TeV. We analyze the flavor components in jet-like environments. We introduce a definition for surrounding cones/belts and investigate flavor dependence and correlation of different hadron species produced in jets. Here, we focus on proton-triggered correlations. Our analysis can be extended for heavy ion collisions.
We have developed prototypes of GEM-like detectors with resistive electrodes to be used as RICH photodetectors equipped with CsI photocathodes. The main advantages of these detectors are their ...intrinsic spark-protection and possibility to operate at high gain (∼10
5) in many gases including poorly quenched ones, allowing for the adoption of windowless configurations in which the radiator gas is also used in the chamber. Results of systematic studies of the resistive GEMs combined with CsI photocathodes are presented: their quantum efficiency, rate characteristics, long-term stability, etc. On the basis of the obtained results, we believe that the new detector will be a promising candidate for upgrading the ALICE RICH detector.
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