A varied and charming collection of 17 papers that bring something new about the people from many countries and backgrounds who traveled to, from and within Egypt and the Near East, either singly or ...as a group, and explored, observed and recorded, or stayed for a short period of time to improve their health or simply to enjoy the experience. While some travelers kept a diary or journal that has survived until today, others did not. Their travels have to be extracted from the wide range of manuscript sources that are thankfully retained in libraries and archives, or which still remain with their descendants. Sometimes, the name of a traveler is only contained in a few words within a single piece of correspondence or journal entry, yet from such small beginnings and through detective work to link the chance meetings between travelers with a location, or news of a shared event, it is often possible to chart part of a traveler’s journey and bring to life a person who has long been forgotten. These minor characters and their travails often bring a new perspective to well-known places and events.
Sir John Young, later Lord Lisgar (1807–76) (Fig. 1.1), a Liberal politician who ended his career as Governor-General of Canada, was first posted overseas in 1855 as High Commissioner for the Ionian ...Islands (Fig. 1.2). His tenure of this office has been overshadowed by its final months in 1858–59, which overlapped with Gladstone’s mission to the Ionian Islands as High Commissioner Extraordinary. This episode is well documented, not only by official sources but also by the large amount of manuscript and printed material about the Islands which is available for research at the residential library that Gladstone founded
Biographical outline of William Trumbull the elder, who died in 1635, giving known details of his family, early life and education, establishment at court as clerk of the Privy Council and the ...circumstances of his appointment as English Resident at Brussels. Sketches his involvement in the Corona Regia libel case which became a personal obsession, comments on his supposed lack of ambition, his investments in land, commercial ventures and finances, and his letters to his son. Notes brief parliamentary career, award of Easthampstead Park, appointment as Berkshire J.P. and to several royal commissions, and aspects of his will.
The effectiveness of oral HIV preexposure prophylaxis (PrEP) strongly depends on maintaining adherence. We investigated the association between substance use and PrEP adherence, as well as incident ...sexually transmitted infections (STIs) in a high-risk cohort of 394 participants (391 men who have sex with men and 3 transgender women) who were enrolled in a PrEP demonstration project. We assessed baseline and ongoing substance use over a 48-week period for stimulants and nonstimulant substances and for each substance separately. We measured PrEP adherence by using dried blood spots to obtain levels of tenofovir diphosphate. No differences in these levels were found between substance users and nonsubstance users. Baseline stimulant use was strongly associated (odds ratio 3.4; p<0.001) with incident STIs during the study. Thus, PrEP adherence was not decreased by substance use. Because substance users had increased rates of STIs, indicating higher-risk behavior, they might be excellent candidates for PrEP.
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