IntroductionGallbladder carcinoma is a rare but aggressive cancer of adults that affects females more than males. Its occurrence is more common in the regions of South America and Asia. Chronic ...inflammation and cholelithiasis are frequently associated risk factors of gallbladder carcinoma. The incidental discovery of a gallbladder carcinoma during cholecystectomy, gross or microscopic examination of the unsuspected gallbladder specimens is termed incidental gallbladder carcinoma (IGBC). Considering the lack of extensive studies on gallbladder carcinoma in the Eastern region of India, especially in Jharkhand, this study has been done to present the demographic and clinicopathological characteristics of gallbladder carcinoma in this region.MethodsA retrospective and descriptive study was done at Rajendra Institute of Medical Sciences (RIMS), Ranchi, a tertiary care center in Jharkhand. The study sample comprised 2386 gall bladder cases received in the Department of Pathology over five years, from December 2018 to December 2023.ResultsOf 2368 specimens, 25 cases (n=25) were reported as primary gallbladder carcinoma. The female-to-male ratio was 4:1. Pain was the most common complaint by the patients. Of the 25 cases, 12 were suspected intra-operatively or diagnosed microscopically (IGBC). Most showed a mass at the neck. In six cases, no gross mass/lesion was seen. Cholelithiasis is present in 19/25 cases. Most cases showed adenocarcinoma (not otherwise specified). Out of the adenocarcinoma cases, most were well differentiated. At the time of diagnosis, most were at the pT2 stage. Twelve cases of IGBC were found. Eight out of 12 IGBC were early-stage carcinoma when diagnosed.ConclusionTwenty-five cases of gallbladder carcinoma were diagnosed in the last five years in our center, with 19 (76%) of them associated with cholelithiasis. Twelve (48%) of the cases were incidentally diagnosed either preoperatively or during gross/microscopic examination, and eight (66%) of those were discovered early, out of which five (62.5%) were observed to be in the T1b stage. At this stage, there is a diversion from the general surgical management of gallbladder carcinoma for a better prognosis. This underscores the significance of routine histopathological examination of gallbladder specimens, even if there is no preoperative suspicion of gallbladder carcinoma.
The transfer of interocclusal data from the patient's mouth to articulators utilizing various types of recording media is necessary for the production of dental prostheses. Occlusal errors in the ...final prosthesis result from any discrepancies in these interocclusal records.
The purpose of this study was to assess the linear dimensional changes in the four elastomeric interocclusal recording materials as well as the material's resistance to compression during the cast mounting on the articulator.
All four elastomeric materials showed decreasing stability over time and 2 mm thickness showed the highest compression resistance with minimal articulation error.
Dimensional stability depends on material and time factors, and compressive resistance decreases with increasing thickness.
Background The incidence of head and neck carcinoma is increasing. The use of an intraoperative frozen section plays a vital role in the evaluation of margin status in patients undergoing surgery for ...oral squamous cell carcinoma. A negative margin is not only an indication of successful surgery but also decreases the recurrence of disease and improves the overall survival of patients. Aims and objective The aim of this study is to assess the accuracy of margin in patients undergoing surgery for oral squamous cell carcinoma by intraoperative frozen section and compare it with conventional histopathological examination. Methodology The approach of our study was a hospital-based prospective study conducted on 28 patients diagnosed with oral squamous cell carcinoma. A frozen section was done on all patients undergoing surgery and compared with histopathological examination. Results Out of 28 patients undergoing surgery, the incidence of males was more than females, with a ratio of 6:1. The most common site of the tumor was left buccal mucosa comprising 28.57%, followed by gingivobuccal sulcus comprising 17.85%. In our study, the frozen assessed margin showed a sensitivity of 58.33%, specificity of 98.76%, and accuracy of 95.25%. Conclusion Frozen section is a reliable method for confirmation of margin accuracy and thus reduces the chance of re-surgery and recurrence of disease and increases overall patient survival.
An immediate surgical obturator is necessary for maxillectomy procedures to minimize functional disabilities in speech, swallowing, and egress of food and liquid into the surgical defect. Sometimes ...the extent of the tumor may be such that it may even require the removal of the maxillary sinus along with resection of the orbital floor. The resected orbital floor can be surgically reconstructed with autogenous soft and/or hard tissues or with alloplastic materials. This clinical report highlights one such situation where the surgical resection of the maxilla and the orbital floor were rehabilitated with an immediate surgical obturator extending to the orbital floor to support the visual apparatus.
Acute promyelocytic leukemia (APML) is a myeloid leukemia classified as M3-AML. It is known for its bleeding diathesis, which is predominantly driven by disseminated intravascular coagulation and ...primary hyperfibrinolysis. However, thrombotic events are relatively less common. A combination of bleeding and thrombotic events is rare and poses a challenge in management. We present a case of acute promyelocytic leukemia complicated by deep venous thrombosis, pulmonary thromboembolism, and hematemesis.
Although Himalayan P waves are not uncommon in congenital heart diseases involving the tricuspid valve, it is rare in pediatric idiopathic restrictive cardiomyopathy. We are presenting one of the ...tallest P waves in literature, the Himalayan P in a toddler with idiopathic restrictive cardiomyopathy. Additionally, we reviewed the literature on the value of electrocardiograms in the evaluation of restrictive cardiomyopathy.
Right Atrial Lateral Wall Aneurysm Kumar, Swasthi S.; Mondal, Sudipta; Banerjee, Saurav
Indian journal of clinical cardiology,
01/2024
Journal Article
Recenzirano
Odprti dostop
Right atrial aneurysm (RAA) is a rare congenital anomaly. It usually occurs due to dysplasia of the atrial myocardium or localized absence of pericardium. We present a case of asymptomatic RAA in an ...adolescent, which was detected incidentally because of a bulge in the right heart border.
