Interjoint coordination in multi-jointed limbs is essential for the generation of functional locomotor patterns. Here we have focused on the role that sensory signals from the coxa-trochanteral (CT) ...joint play in patterning motoneuronal activity of the femur-tibia (FT) joint in the stick insect middle leg. This question is of interest because when the locomotor system is active, movement signals from the FT joint are known to contribute to patterning of activity of the central rhythm-generating networks governing the CT joint. We investigated the influence of femoral levation and depression on the activity of tibial motoneurons. When the locomotor system was active, levation of the femur often induced a decrease or inactivation of tibial extensor activity while flexor motoneurons were activated. Depression of the femur had no systematic influence on tibial motoneurons. Ablation experiments revealed that this interjoint influence was not mediated by signals from movement and/or position sensitive receptors at the CT joint, i.e., trochanteral hairplate, rhombal hairplate, or internal levator receptor organ. Instead the influence was initiated by sensory signals from a field of campaniform sensillae, situated on the proximal femur (fCS). Selective stimulation of these fCS produced barrages of inhibitory postsynaptic potentials (IPSPs) in tibial extensor motoneurons and activated tibial flexor motoneurons. During pharmacologically activated rhythmic activity of the otherwise isolated mesothoracic ganglion (pilocarpine, 5 x 10(-4) M), deafferented except for the CT joint, levation of the femur as well had an inhibitory influence on tibial extensor motoneurons. However, the influence of femoral levation on the rhythm generated was rather labile and only sometimes a reset of the rhythm was induced. In none of the preparations could entrainment of rhythmicity by femoral movement be achieved, suggesting that sensory signals from the CT joint only weakly affect central rhythm-generating networks of the FT joint. Finally, we analyzed the role of sensory signals from the fCS during walking by recording motoneuronal activity in the single middle leg preparation with fCS intact and after their removal. These experiments showed that fCS activity plays an important role in generating tibial motoneuron activity during the stance phase of walking.
Structure function measurements and kinematic reconstruction at HERA Bassler, Ursula; Bernardi, Gregorio
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
05/1999, Letnik:
426, Številka:
2
Journal Article
Recenzirano
Odprti dostop
The procedure used for structure function measurements at HERA is briefly described and related to the properties of kinematic reconstruction. The reconstruction methods of the inclusive deep ...inelastic scattering variables are reviewed and their sensitivity to the energy and angle miscalibrations are discussed in detail. New prescriptions are introduced and related to the standard methods in order to optimize the
F
2 structure function measurement over the widest kinematic range, both in the low
x, low
Q
2 and in the high
x, high
Q
2 regions. The prospects for the future high
Q
2 studies are briefly discussed.
Higgs boson studies at the Tevatron Agnew, J. P.; Annovi, A.; Bandurin, D. V. ...
Physical review. D, Particles, fields, gravitation, and cosmology,
09/2013, Letnik:
88, Številka:
5
Journal Article
Recenzirano
Odprti dostop
We combine searches by the CDF and DO Collaborations for the standard model Higgs boson with mass in the range 90- 200 GeV /c super(2) produced in the gluon-gluon fusion, WH, ZH, ttH, and vector ...boson fusion processes, and decaying in the H arrow right bb, H arrow right W super(+)W super(-), H arrow right ZZ, H arrow right tau super(+)tau super(-), and H arrow right gamma gamma modes. The data correspond to integrated luminosities of up to 10 fb super(-1) and were collected at the Fermilab Tevatron in pp collisions at radicals = 1.96 TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140 GeV /c super(2). The local significance corresponds to 3.0 standard deviations at mH = 125 GeV /c super(2), consistent with the mass of the Higgs boson observed at the LHC, and we expect a local significance of 1.9 standard deviations. We separately combine searches for H arrow right bb, H arrow right W super(+)W super(-), H arrow right tau super(+)t super(-), and H arrow right gamma gamma . The observed signal strengths in all channels are consistent with the presence of a standard model Higgs boson with a mass of 125 GeV /c super(2).
In a form of top-down analysis, the femur-tibia control system of stick insects is investigated. Open-loop experiments show that it is mainly velocity-sensitive with an extremely low ...velocity-threshold, that it possesses a very high gain and that it has only a very small phase reserve and thus works close to instability. The closed-loop system generates catalepsy. The system consists of a single sense organ with approximately 80 sense cells with known characteristics, a small number of interneurones (mainly non-spiking ones) and a small number of motor neurones. The characteristics of the whole system can quantitatively be attributed to the characteristics of its elements. The gain of the loop is state-dependent and the system is 'switched off' during active movements and replaced by a control system with different attributes. It is discussed that most of the characteristics of this system are, at least qualitatively, similar to joint control systems in other animals. Because the described system can be more easily investigated than other systems (especially in vertebrates) it can serve as a model against which more complicated joint control loops may be compared.
The extremely slow return movements observed in stick insects (phasmids) after imposed changes in posture are termed catalepsy. In the literature, catalepsy is treated as a behavioural component of ...the twig mimesis observed in walking stick insects. It is produced by the high gain of the velocity-sensitive component of the relevant joint control systems and by the non-linear dependency of its time constant on movement velocity. The high gain, in turn, causes the system to work close to instability, and this may have driven the evolution of gain control mechanisms. Although these statements represent plausible assumptions, based on correlated occurrence, they remain largely hypothetical like many ideas concerning evolutionary tendencies. To test these hypotheses, we studied catalepsy and the relevant properties of the femur-tibia control system in the middle and hind legs of Prosarthria teretrirostris.cf. Prosarthria teretrirostris is a proscopiid closely related to grasshoppers and locusts. With its slender, green-to-brown body and legs, it shows clear morphological twig mimesis, which has evolved independently of the well-known twig mimesis in stick insects. The animals show clear catalepsy. The main properties of femur-tibia joint control are remarkably similar between proscopiids and stick insects (e.g. the marked sensitivity to movement velocity rather than to joint position and the non-linear dependency of the time constants of response decay on movement velocity), but there are also important differences (habituation and activity-related mechanisms of gain control are absent). Together, these results validate the main concepts that have been developed concerning the neural basis and evolution of catalepsy in stick insects and its relationship to twig mimesis, while demonstrating that ideas on the role of habituation and gain control should be refined.
We present the results of the combination of searches for the standard model Higgs boson produced in association with a W or Z boson and decaying into bb using the data sample collected with the D0 ...detector in pp collisions at √s = 1.96 TeV at the Fermilab Tevatron Collider. We derive 95% C.L. upper limits on the Higgs boson cross section relative to the standard model prediction in the mass range 100 GeV ≤ M(H) ≤ 150 GeV, and we exclude Higgs bosons with masses smaller than 102 GeV at the 95% C.L. In the mass range 120 GeV ≤ M(H) ≤145 GeV, the data exhibit an excess above the background prediction with a global significance of 1.5 standard deviations, consistent with the expectation in the presence of a standard model Higgs boson.
We present the first search for CPT-violating effects in the mixing of ${B_s^0}$ mesons using the full Run II data set with an integrated luminosity of 10.4 fb$^{-1}$ of proton-antiproton collisions ...collected using the D0 detector at the Fermilab Tevatron Collider. We measure the CPT-violating asymmetry in the decay $B_s^0 \to \mu^\pm D_s^\pm$ as a function of celestial direction and sidereal phase. We find no evidence for CPT-violating effects and place limits on the direction and magnitude of flavor-dependent CPT- and Lorentz-invariance violating coupling coefficients. We find 95\% confidence intervals of $\Delta a_{\perp} < 1.2 \times 10^{-12}$ GeV and $(-0.8 < \Delta a_T - 0.396 \Delta a_Z < 3.9) \times 10^{-13}$ GeV.
We report the observation of a narrow structure, $X(5568)$, in the decay sequence $X(5568) \rightarrow B_s^0 \pi^{\pm}$, $B_s^0 \rightarrow J/\psi \phi$, $J/\psi\rightarrow \mu^+ \mu^-$, $\phi ...\rightarrow K^+K^-$. This is the first observation of a hadronic state with valence quarks of four different flavors. The mass and natural width of the new state are measured to be $m = 5567.8 \pm 2.9 {\rm \thinspace (stat)} ^{+0.9}_{-1.9} {\rm \thinspace (syst)}$ MeV/$c^2$ and $\Gamma = 21.9 \pm 6.4 {\rm \thinspace (stat)} ^{+5.0}_{-2.5} {\rm \thinspace (syst)} $ MeV/$c^2$, and the significance including look-elsewhere effect and systematic uncertainties is 5.1$\sigma$. The observation is based on$10.4~\rm{fb^{-1}}$ of $p \overline p $ collision data at $\sqrt{s}$ = 1.96 TeV collected by the D0 experiment at the Fermilab Tevatron collider.
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