A comparison was made of the sensitivity of ECG, ultrastructural heart pathology, and plasma enzymes CK-MB and alpha-HBDH as methods to assess doxorubicin cardiotoxicity in adult beagle dogs given ...doxorubicin 30 mg/m2 i.v. once a week for three times. A progressive increase in JT and QT intervals, in corrected JT (JTc) and QT (QTc) intervals as well as a reduction in both T wave amplitude and RR duration, were observed in doxorubicin-treated dogs; the electrocardiogram (ECG) abnormalities were associated with doxorubicin-induced ultrastructural changes in cardiac tissue, consisting of dilation of the sarcoplasmic reticulum, multiform, flasklike invaginations of T-tubules containing electrondense material, and interruption of the junctional sarcoplasmic reticulum, which became more severe as the observation period progressed. On the contrary, doxorubicin treatment was associated with transient changes in plasma CK-MB and alpha-HBDH, which were unrelated to the severity of chronic cardiotoxicity. Overall results suggest that the monitoring of the ECG parameters related to the repolarization of the cardiac muscle, and particularly JT and JTc, might be regarded as a noninvasive method for the study of doxorubicin cardiotoxocity in the dog.
Book reviews Calabria, Antonio; Marino, John A.; Symcox, Geoffrey ...
Journal of Modern Italian Studies,
19/6/1/, Letnik:
4, Številka:
2
Book Review
Recenzirano
Camillo Tutini and Marino Verde (1997) Racconto della sollevazione di Napoli accaduta nell'anno MDCXLVII, ed. Pietro Messina (Rome: Istituto storico italiano per l'età moderna e contemporanea).
Paolo ...Macry ( 1997) Giocare la vita. Storia del lotto a Napoli tra Sette e Ottocento (Rome: Donzelli editore), pp. 1-144, 30,000 lire, ISBN 88-7989-354-8 paperback.
Maria Teresa Silvestrini (1997) La politica della religione. Il governo ecclesiastico nello Stato sabaudo del XVIII secolo (Florence: Leo S. Olschki editore; Fondazione Luigi Firpo, Studi e Testi, no. 7), pp. 1-427.
Luciano Allegra (1996) Identità in bilico. Il ghetto ebraico di Torino nel Settecento (Torino: Zamorani), pp. 1-341, 36,000 lire, ISBN 88-7158-050-8.
Luigi Zangheri (1996) Ftste e apparati nella Toscana dei Lorena 1737-1859 (Florence: Olschki; Biblioteca dell''Archivium Romanicum' - serie I: storia, letteratura, paleografìa 266), pp. I-33I, 115 illustrations and extensive bibliography, 69,000 lire, paperback.
Barbara Maffiodo (1996) I borghesi taumaturghi. Medici, cultura scientifica e società in Piemonte fra crisi dell'antico regime ed età napoleonica (Florence: Olschki), pp. 1-336, 70,000 lire, ISBN 88-222-441-9.
Olivier Faron (1997) La Ville des destins croisés. Recherches sur la société milanaise du X/Xe siècle (1811-1860) (Rome: Ecole Française de Rome, Palais Farnèse; Bibliothèque des Ecoles Françaises d'Athènes et de Rome, fascicule 297), pp. i-x, 1-603, ISBN 2-7283-0377-0 hardback.
Anthony L Cardoza (1997) Aristocrats in Bourgeois Italy. The Piedmontese Nobility, 1861-1930 (Cambridge: Cambridge University Press), pp. i-xii, 1-248.
Richard J. Golsan (ed.) (1998) Fascism's Return: Scandal, Revision and Ideology since 1980 (Lincoln: University of Nebraska Press), pp. i-ix, 1-330, ISBN 0-6032-7071-2; John Pollard (1998) The Fascist Experience in Italy (London: Routledge), pp. i-xiii, 1-158, ISBN 0-415-11631-7.
R. J. B. Bosworth (1998) The kalian Dictatorship. Problems and Perspectives in the Interpretation of Mussolini and Fascism (London: Arnold), pp. i-x, 1-269, ISBN 0-340-67728-7 hardback; ISBN 0-340-67727-9 paperback.
Robin Pickering-Iazzi (1997) Politics of the Visible. Writing Women, Culture, and Fascism (Minneapolis: University of Minnesota Press), pp. 1-287, ISBN 0-8166-2923-4 paperback.
Tom Behan (1997) The Long Awaited Moment the Working Class and the Italian Communist Party in Milan, 1943-1948 (New York: Peter Lang Publishing), pp. I-328, $49.95, ISBN 0-8204-2674-1 hardback.
Giulio Sapelli (1993) Sul capitalismo italiano. Trasformazione o declino (Milan: Feltrinelli), pp. 1-1 64,25,000 lire, ISBN 88-07-09035-X paperback.
Filippo Peschiera (ed.) (1994) Sindacato industria e stato negli anni dell'emergenza: Storia delle relazioni industriali in Italia dal 1972 al 1983 (Florence: Felice Le Monnier), pp. 1-468,50,000 lire, ISBN 88-00-84047-7 paperback.
Daniele Marchesini (1998) Coppi e Banali (Bologna: II Mulino; L'identità nazionale), 18,000 lire, ISBN 88-15-06715-9.
Gianni Perona (ed.) (1994) Gli italiani in Francia 1938-1946, Mezzosecolo materiali di ricerca storica #9 (Milan: Franco Angeli), pp. i-ix, 1-425, 60,000 lire, ISBN 88-204-8615-6 paperback.
Jeffrey Cole (1997) The New Racism in Europe: a Sicilian Ethnography (Cambridge and New York: Cambridge University Press), pp. 1-133 plus appendices, ISBN 0-52I-S8493-0.
Nicholas DeMaria Harney (1998) Eh, Paesani Being kalian in Toronto (Toronto: University of Toronto Press), pp. 1-209, C$17.95, ISBN 0-8020-8099-5 paperback; C$55.00, ISBN 0-8020-4259-7 hardback.
Luciano Carracciolo and Michel Korinman (eds) (1998) Italy and the Balkans (Washington, DC: The Center for Strategic and International Studies), pp. i-vii, l-l00, ISBN 0-89206-344-0 paperback.
