Asian guidelines for condyloma acuminatum Sindhuja, Tekumalla; Bhari, Neetu; Gupta, Somesh
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy,
July 2022, 2022-Jul, 2022-07-00, 20220701, Letnik:
28, Številka:
7
Journal Article
Recenzirano
The present guidelines aim to provide comprehensive information on genital condyloma acuminata, including the epidemiology, clinical features, diagnosis and management. The guidelines provide ...evidence-based recommendations on the diagnosis, prevention and treatment of genital condyloma acuminata in adults in Asia, including patients with HIV co-infection.
A PubMed search was performed, using the keywords “condyloma acuminata”, “anal wart”, “anogenital wart”, “genital wart” and “genital HPV”. A total of 3031 results were found in publications during last six years. A careful review of the titles and abstracts was done to find all the studies pertaining to epidemiology, clinical features, diagnosis, treatment and prevention of condyloma acuminata.
Various diagnostic procedures described are:
1. PCR (LE: 2b).
2. Serology (LE: 2b).
3. In-situ hybridization (LE: 3).
1. Vaccination (LE: 1a): Quadrivalent vaccine reduced the frequency of anogenital warts in both vaccinated and unvaccinated contacts.
According to the update Advisory Committee on Immunization Practices (ACIP) recommendations, the following protocol is recommended:
(a). HPV vaccination at age 11 or 12 years for both males and females.
(b). Catch-up vaccination for all persons through age 26 years.
(c). Shared clinical decision-making regarding potential HPV vaccination for persons aged 27–45 years, who are at risk of new HPV infection.
2. Male circumcision (LE: 2a): conflicting evidence.
In HIV-affected individuals, the course of HPV is more aggressive, with a greater risk of treatment resistance, increased chances of intraepithelial neoplasia as well as cancers.
Physician administered.
1. Photodynamic therapy (LE: 1a).
2. Laser (LE: 2b).
3. Surgery (LE: 1a).
4. Electrosurgery (LE: 2c).
5. Cryotherapy (LE: 1b).
6. Immunotherapy (LE: 1b).
7. Podophyllin (LE: 1b).
Provider administered.
1. Imiquimod 5%(LE: 1a).
2. Podophyllotoxin (LE: 1b).
3. Sinecatechins (LE: 1a).
4. Cidofovir (LE: 3).
5. 5- Fluorouracil (LE: 1a).
6. Interferon (LE: 1a).
Asian guidelines for syphilis Mehta, Nikhil; Bhari, Neetu; Gupta, Somesh
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy,
August 2022, 2022-Aug, 2022-08-00, 20220801, Letnik:
28, Številka:
8
Journal Article
Blaschkoid blue vitiligo Jassi, Rubina; Mehta, Nikhil; Ramam, M ...
International journal of dermatology,
February 2019, Letnik:
58, Številka:
2
Journal Article
Vascular Malformations Bhari, Neetu; Agarwal, Akash; Asritha, C. V. V. ...
Indian Dermatology Online Journal,
05/2024, Letnik:
15, Številka:
3
Journal Article
Recenzirano
Odprti dostop
Abstract Vascular malformations are intricate anomalies of the circulatory system, presenting a diverse array of clinical manifestations, and posing significant challenges in diagnosis and treatment. ...The pathogenesis of vascular malformations is explored through the lens of genetic and molecular mechanisms, shedding light on the pivotal role of somatic mutations and dysregulated signaling pathways. Clinical presentations of vascular malformations are widely variable, ranging from cosmetic concerns to life-threatening complications. The utility of imaging techniques, such as magnetic resonance imaging (MRI), computed tomography (CT), and angiography, are discussed in detail, emphasizing their role in precise delineation and characterization. Therapeutic strategies for vascular malformations are multifaceted, considering factors such as lesion size, location, potential complications, and patient-specific factors. Traditional interventions, including surgical excision and embolization, are appraised alongside emerging approaches like targeted molecular therapies and minimally invasive procedures. The manuscript underscores the need for an individualized treatment approach, optimizing outcomes while minimizing risks and complications. In summation, this manuscript offers a comprehensive analysis of vascular malformations, encompassing their underlying pathogenesis, clinical nuances, diagnostic methods, and therapeutic considerations. By synthesizing current knowledge and highlighting gaps in understanding, this review serves as a valuable resource for clinicians, researchers, and medical practitioners, fostering an enhanced comprehension of vascular malformations and paving the way for improved patient care and innovative research endeavors.
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