The combination is presented of searches for a standard model (SM) Higgs boson in eight decay modes: H → γγ, H → ττ, H → bb, H → WW* → 2ℓ2v, H → ZZ* → 4ℓ, H → ZZ → 2ℓ2τ, H → ZZ → 2ℓ2v, and H → ZZ → ...2ℓ2q. The searches were performed by the CMS Collaboration using 1.1-1.7 fb−1 of integrated luminosity, depending on the analysis. No excess compatible with a SM Higgs signal has been observed; the largest excursion of the observed data from the expected background has a probability of 0.4 after taking into account the look-elsewhere effect. The SM Higgs boson is excluded at 95% C.L. in three mass ranges 145-216, 226-288, and 310-400 GeV/c2, while the expected exclusion range is 130-440 GeV/c2.
The CMS detector will start its operation in the end of 2007. Until that time great care must be taken in order to assure that hardware operation is fully understood. In this paper an example of how ...emulation software helps achieving this goal in the CMS Level-1 RPC Trigger system is presented. The design of the RPC trigger allows to insert sets of so-called test pulses at any stage of the hardware pipeline. Reading out data from different stages is also possible. Such design allows for easy debugging of the trigger hardware by comparing hardware and software emulation values, since the software and hardware algorithms are identical.
The combination is presented of searches for a standard model (SM) Higgs boson in eight decay modes: H->gamma,gamma, H->tau,tau, H->bb, H->WW->2l2nu, H->ZZ->4l, H->ZZ->2l2tau, H->ZZ->2l2nu, and ...H->ZZ->2l2q. The searches were performed by the CMS Collaboration using 1.1-1.7 fb-1 of integrated luminosity, depending on the analysis. No excess compatible with a SM Higgs signal has been observed; the largest excursion of the observed data from the expected background has a probability of 0.4 after taking into account the look-elsewhere effect. The SM Higgs boson is excluded at 95% C.L. in three mass ranges 145-216, 226-288, and 310-400 GeV/c2, while the expected exclusion range is 130-440 GeV/c2.
The
gene encodes the regulatory subunit of NADPH oxidase, which maintains the redox state within cells and in the blood vessels. That led us to investigate the course of coronary artery disease (CAD) ...with regards to
polymorphisms. Thus, we recruited 1197 subjects with coronary atherosclerosis and observed them during 7-year follow-up. Three
polymorphisms: c.214C>T (rs4673), c.-932G>A (rs9932581), and c.*24G>A (1049255) were studied for an association with death, major adverse cardiovascular events (MACE) and an elective percutaneous coronary intervention or coronary artery bypass grafting (PCI/CABG). We found an association between the
c.214C>T polymorphism and two end points: death and PCI/CABG.
c.214TT genotype was associated with a lower risk of death than C allele (9.5% vs. 21%,
< 0.05) and a higher risk of PCI/CABG than C allele (69.3% vs. 51.7%,
< 0.01). This suggests that the
c.214TT genotype may be a protective factor against death OR = 0.47 (95%CI 0.28-0.82;
< 0.01), while also being a risk factor for an elective PCI/CABG OR = 2.36 (95%CI 1.15-4.82;
< 0.05). Thus, we hypothesize that among patients with coronary atherosclerosis, the
c.214TT genotype contributes to atherosclerotic plaque stability by altering the course of CAD towards chronic coronary syndrome, thereby lowering the incidence of fatal CAD-related events.
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