Anetoderma is a rare elastolytic disorder included within the group of cutaneous atrophies. Its pathogenesis is not yet clearly established, but immunological mechanisms could play an important role ...in dermal elastolysis. It has been associated with different autoantibodies and autoimmune disorders. We present a case of anetoderma in a systemic lupus erythematosus patient with anti-proliferating-cell-nuclear-antigen and antiphospholipid antibodies, highlighting the peculiarities of such an association.
Steatocystoma multiplex is characterized by the development of numerous steatocystomas. The condition has occasionally been related to congenital bilateral preauricular sinuses. Herein, we present ...the third case of such an association, a 34‐year‐old male who was born with bilateral preauricular sinuses that were surgically repaired. When he was 14 years old, he presented with multiple steatocystomas on his forehead and temples, one of which was biopsied. There was no family history of the condition.
"Mechanic's hands" are a characteristic cutaneous sign of idiopathic inflammatory myositis. We describe the case of a 61-year-old male patient who was diagnosed with idiopathic polymyositis and ...non-specific interstitial lung disease in 1999, and three years later developed scaly, fissured hyperkeratotic lesions on the lateral and palmar surfaces of the first three fingers of both hands, with little pruritus. The presence of the anti-Jo-1 antisynthetase antibody in the patient's serum, the finding of skin lesions characteristic of "mechanic's hands" and the patient's other systemic clinical manifestations made it possible to establish the diagnosis of "antisynthetase syndrome."
Nevus of Ota associated with ipsilateral deafness ALVAREZ-CUESTA, César Cosme; RAYA-AGUADO, Cristina; VAZQUEZ-LOPEZ, Francisco ...
Journal of the American Academy of Dermatology,
11/2002, Letnik:
47, Številka:
5
Journal Article
Recenzirano
Nevus of Ota is a benign pigmentary disorder that involves the skin innervated by the first and second branches of the trigeminal nerve. It is a dermal melanocytosis frequent in Oriental persons but ...uncommon in white persons. We report a case of nevus of Ota in a white woman emphasizing the wide extension of the pigmentation and its association with ipsilateral sensorineural hypoacusia. (J Am Acad Dermatol 2002;47:S257-9.)
Linear epidermal nevi are believed to be caused by an autosomal dominant lethal mutation that can only be expressed by mosaicism. Becker's nevus can be explained by paradominant inheritance which is ...only manifested clinically by an acquired loss of heterozygosity. We present the case of a 16-year-old female with an epidermal nevus located on the left side of the neck, and also a Becker's nevus located on the ipsilateral shoulder. It is interesting to speculate that this supposed double mosaicism could be another example of "twin spotting" or non-allelic didymosis, although the possibility that this is a chance association cannot be ruled out, as the lesions are not closely associated.
El eritema indurado de Bazin es poco frecuente en la edad pediátrica. Presentamos el caso de una niña de 12 años procedente de China remitida para estudio por sospecha de eritema nudoso de larga ...evolución y prueba de tuberculina positiva (20 mm). La paciente no presentaba otros síntomas. En la exploración física se observaban nódulos violáceos, localizados en ambas regiones pretibiales, pero también en ambas pantorrillas. La radiografía de tórax fue normal. Se obtuvo muestra para biopsia, que mostró una paniculitis de predominio lobulillar con presencia de granulomas. La detección de micobacterias mediante cultivo y reacción en cadena de la polimerasa en la muestra fue negativa. Se aisló Mycobacterium tuberculosis en una de tres muestras de jugo gástrico. Se trató con isoniacida, rifampicina, pirazinamida y etambutol con curación de las lesiones. Este caso resalta la importancia de sospechar eritema indurado en las formas atípicas de eritema nudoso y de investigar exhaustivamente la existencia de una tuberculosis activa en estos casos.
Objective. To demonstrate our experience in the treatment of head and neck cutaneous melanoma and the regional lymph nodes staging, by the sentinel lymph nodes biopsy technique. Methods. We analyze ...the cases of head and neck cutaneous melanoma treated during the last 3 years. Patients with cervical and/or facial metastases were treated by neck dissection plus parotidectomy if peripheral or intra-parotid nodes were affected. In the patients with primary tumours, a preoperatory biopsy and a whole body extension study were performed. After that, the cervical and facial sentinel lymph nodes and the primary tumour were resected. The defects created were reconstructed by means of local or regional cutaneous flaps. Results. Cutaneous melanoma associates with an excellent long-term prognosis when is detected and treated in a precocious stage. The cervical and facial sentinel lymph nodes biopsy technique is feasible in head and neck cutaneous melanomas. Conclusion. Sentinel node biopsy technique is considered the elective procedure for head and neck cutaneous melanoma regional staging. It improves the effectiveness and sensibility of the histopathologic study, due to the capacity to select the cervical and facial lymphatic nodes with more probability of have metastases. Objetivo: demostrar nuestra experiencia en el tratamiento del melanoma cutáneo de cabeza y cuello, así como en el estadiaje ganglionar regional a través de la detección y biopsia de los ganglios centinelas cervicofaciales.
Métodos: analizamos los casos de melanoma de cabeza y cuello tratados a lo largo de los últimos tres años. Los pacientes que no fueron enviados con metástasis cervicofaciales fueron tratados mediante linfedenectomías cervicales acompañadas de parotidectomías si existían ganglios peri o intraparotídeos afectos. En los pacientes enviados sin resecar el tumor primario, tras la biopsia preoperatoria y el estudio de extensión, se realizó la identificación y exéresis de los ganglios centinelas cervicofaciales, la resección del primario y la reconstrucción del defecto creado mediante colgajos locorregionales.
Resultados: el melanoma se asocia con un excelente pronóstico a largo plazo si se detecta y trata en estadios precoces. La técnica de la identificación y exéresis de los ganglios centinelas cervicofaciales es factible en los melanomas de cabeza y cuello.
Conclusión: la técnica de detección y biopsia de los ganglios centinelas regionales se considera el procedimiento de elección para realizar el estadiaje ganglionar regional en el melanoma de cabeza y cuello. Permite aumentar la eficacia y sensibilidad del estudio histopatológico, al seleccionar los ganglio linfáticos cervicofaciales con mayor probabilidad de encontrar focos metastásicos.
