Topological quantum phase transitions are characterized by changes in global topological invariants. These invariants classify many-body systems beyond the conventional paradigm of local order ...parameters describing spontaneous symmetry breaking. For noninteracting electrons, it is well understood that such transitions are continuous and always accompanied by a gap closing in the energy spectrum, given that the symmetries protecting the topological phase are maintained. Here, we demonstrate that a sufficiently strong electron-electron interaction can fundamentally change the situation: we discover a topological quantum phase transition of first-order character in the genuine thermodynamic sense that occurs without a gap closing. Our theoretical study reveals the existence of a quantum critical endpoint associated with an orbital instability on the transition line between a 2D topological insulator and a trivial band insulator. Remarkably, this phenomenon entails unambiguous signatures related to the orbital occupations that can be detected experimentally.
Mott insulators are "unsuccessful metals" in which Coulomb repulsion prevents charge conduction despite a metal-like concentration of conduction electrons. The possibility to unlock the frozen ...carriers with an electric field offers tantalizing prospects of realizing new Mott-based microelectronic devices. Here we unveil how such unlocking happens in a simple model that shows the coexistence of a stable Mott insulator and a metastable metal. Considering a slab subject to a linear potential drop, we find, by means of the dynamical mean-field theory, that the electric breakdown of the Mott insulator occurs via a first-order insulator-to-metal transition characterized by an abrupt gap collapse in sharp contrast to the standard Zener breakdown. The switch on of conduction is due to the field-driven stabilization of the metastable metallic phase. Outside the region of insulator-metal coexistence, the electric breakdown occurs through a more conventional quantum tunneling across the Hubbard bands tilted by the field. Our findings rationalize recent experimental observations and may offer a guideline for future technological research.
The fifth "Melanoma Bridge Meeting" took place in Naples, December 1-5th, 2015. The main topics discussed at this meeting were: Molecular and Immuno advances, Immunotherapies and Combination ...Therapies, Tumor Microenvironment and Biomarkers and Immunoscore. The natural history of cancer involves interactions between the tumor and the immune system of the host. The immune infiltration at the tumor site may be indicative of host response. Significant correlations were shown between the levels of immune cell infiltration in tumors and patient's clinical outcome. Moreover, incredible progress comes from the discovery of mutation-encoded tumor neoantigens. In fact, as tumors grow, they acquire mutations that are able to influence the response of patients to immune checkpoint inhibitors. It has been demonstrated that sensitivity to PD-1 and CTLA-4 blockade in patients with advanced NSCLC and melanoma was enhanced in tumors enriched for clonal neoantigens. The road ahead is still very long, but the knowledge of the mechanisms of immune escape, the study of tumor neo-antigens as well as of tumor microenvironment and the development of new immunotherapy strategies, will make cancer a more and more treatable disease.
We investigate by means of the time-dependent Gutzwiller approximation the transport properties of a strongly correlated slab subject to Hubbard repulsion and connected with to two metallic leads ...kept at a different electrochemical potential. We focus on the real-time evolution of the electronic properties after the slab is connected to the leads and consider both metallic and Mott insulating slabs. When the correlated slab is metallic, the system relaxes to a steady state that sustains a finite current. The zero-bias conductance is finite and independent of the degree of correlations within the slab as long as the system remains metallic. On the other hand, when the slab is in a Mott insulating state, the external bias leads to currents that are exponentially activated by charge tunneling across the Mott-Hubbard gap, consistent with the Landau-Zener dielectric breakdown scenario.
We study the fate of helical edge states in a quantum spin Hall insulators when the whole system is exposed to strong Coulomb interactions. Using dynamical mean-field theory, we show that the ...dispersion relation of the edge states is strongly affected by Coulomb interactions. In fact, the formerly gapless edge modes become gapped at a critical interaction strength. Interestingly, this critical interaction strength is significantly smaller at the edge than its counterpart in the bulk. Thus, the bulk remains in a topologically nontrivial state at intermediate interaction strengths where the edge states are already gapped out. This peculiar scenario leads to the reconstruction of gapless helical states at the new boundary between the topological bulk and the trivial (Mott insulating) edge. Further increasing the interaction strength triggers the progressive localization on the new boundary, the shrinking of the quantum spin Hall region, and the migration of the helical edge states towards the center of the system. The edge state reconstruction process is eventually interrupted by the Mott localization of the whole sample. Finally, we characterize the topological properties of the system by means of a local Chern marker.
We study the role of electronic spin and valley symmetry in the quantum interference (QI) patterns of the transmission function in graphene quantum junctions. In particular, we link it to the ...position of the destructive QI antiresonances. When the spin or valley symmetry is preserved, electrons with opposite spin or valley display the same interference pattern. On the other hand, when a symmetry is lifted, the antiresonances are split, with a consequent dramatic differentiation of the transport properties in the respective channel. We demonstrate rigorously this link in terms of the analytical structure of the electronic Green function, which follows from the symmetries of the microscopic model, and we confirm the result with numerical calculations for graphene nanoflakes. We argue that this is a generic and robust feature that can be exploited in different ways for the realization of nanoelectronic QI devices, generalizing the recent proposal of a QI-assisted spin-filtering effect A. Valli et al., Nano Lett. 18, 2158 (2018).
One of the pivotal questions in the physics of high-temperature superconductors is whether the low-energy dynamics of the charge carriers is mediated by bosons with a characteristic timescale. This ...issue has remained elusive as electronic correlations are expected to greatly accelerate the electron-boson scattering processes, confining them to the very femtosecond timescale that is hard to access even with state-of-the-art ultrafast techniques. Here we simultaneously push the time resolution and frequency range of transient reflectivity measurements up to an unprecedented level, enabling us to directly observe the ~16 fs build-up of the effective electron-boson interaction in hole-doped copper oxides. This extremely fast timescale is in agreement with numerical calculations based on the t-J model and the repulsive Hubbard model, in which the relaxation of the photo-excited charges is achieved via inelastic scattering with short-range antiferromagnetic excitations.