Spitzer/IRAC selection is a powerful tool for identifying luminous active galactic nuclei (AGNs). For deep IRAC data, however, the AGN selection wedges currently in use are heavily contaminated by ...star-forming galaxies, especially at high redshift. Using the large samples of luminous AGNs and high-redshift star-forming galaxies in COSMOS, we redefine the AGN selection criteria for use in deep IRAC surveys. The new IRAC criteria are designed to be both highly complete and reliable, and incorporate the best aspects of the current AGN selection wedges and of infrared power-law selection while excluding high-redshift star-forming galaxies selected via the BzK, distant red galaxy, Lyman-break galaxy, and submillimeter galaxy criteria. At QSO luminosities of log L sub(2-10 keV)(erg s super(-1)) > or =, slanted 44, the new IRAC criteria recover 75% of the hard X-ray and IRAC-detected XMM-COSMOS sample, yet only 38% of the IRAC AGN candidates have X-ray counterparts, a fraction that rises to 52% in regions with Chandra exposures of 50-160 ks. X-ray stacking of the individually X-ray non-detected AGN candidates leads to a hard X-ray signal indicative of heavily obscured to mildly Compton-thick obscuration (log N sub(H) (cm super(-2)) = 23.5 + or - 0.4). While IRAC selection recovers a substantial fraction of luminous unobscured and obscured AGNs, it is incomplete to low-luminosity and host-dominated AGNs.
While major mergers have long been proposed as a driver of both active galactic nucleus (AGN) activity and the relation, studies of moderate to high-redshift Seyfert-luminosity AGN hosts have found ...little evidence for enhanced rates of interactions. However, both theory and observation suggest that while these AGNs may be fueled by stochastic accretion and secular processes, high-luminosity, high-redshift, and heavily obscured AGNs are the AGNs most likely to be merger-driven. To better sample this population of AGNs, we turn to infrared selection in the CANDELS/COSMOS field. Compared to their lower-luminosity and less obscured X-ray-only counterparts, IR-only AGNs (luminous, heavily obscured AGNs) are more likely to be classified as either irregular ( versus ) or asymmetric ( versus ) and are less likely to have a spheroidal component ( versus ). Furthermore, IR-only AGNs are also significantly more likely than X-ray-only AGNs ( versus ) to be classified either as interacting or merging in a way that significantly disturbs the host galaxy or as disturbed, though not clearly interacting or merging, which potentially represents the late stages of a major merger. This suggests that while major mergers may not contribute significantly to the fueling of Seyfert-luminosity AGNs, interactions appear to play a more dominant role in the triggering and fueling of high-luminosity heavily obscured AGNs.
ABSTRACT We present the catalog of optical and infrared counterparts of the Chandra COSMOS-Legacy Survey, a 4.6 Ms Chandra program on the 2.2 deg2 of the COSMOS field, combination of 56 new ...overlapping observations obtained in Cycle 14 with the previous C-COSMOS survey. In this Paper we report the i, K, and 3.6 m identifications of the 2273 X-ray point sources detected in the new Cycle 14 observations. We use the likelihood ratio technique to derive the association of optical/infrared (IR) counterparts for 97% of the X-ray sources. We also update the information for the 1743 sources detected in C-COSMOS, using new K and 3.6 m information not available when the C-COSMOS analysis was performed. The final catalog contains 4016 X-ray sources, 97% of which have an optical/IR counterpart and a photometric redshift, while 54% of the sources have a spectroscopic redshift. The full catalog, including spectroscopic and photometric redshifts and optical and X-ray properties described here in detail, is available online. We study several X-ray to optical (X/O) properties: with our large statistics we put better constraints on the X/O flux ratio locus, finding a shift toward faint optical magnitudes in both soft and hard X-ray band. We confirm the existence of a correlation between X/O and the the 2-10 keV luminosity for Type 2 sources. We extend to low luminosities the analysis of the correlation between the fraction of obscured AGNs and the hard band luminosity, finding a different behavior between the optically and X-ray classified obscured fraction.
Vending machines for harm reduction (VMHR) are an innovative approach to deliver life-saving materials, information, and treatment for hard-to-reach populations, particularly for persons who inject ...drugs. The current study explores stakeholders' perspectives on the feasibility and acceptability of VMHR in Philadelphia.
From October 2021 to February 2022, we conducted 31 semi-structured interviews with potential end users, staff, and leadership at a local federally qualified health center, and community members. Trained coders extracted themes from interview transcripts across four key domains: materials and logistics, location, access, and community introduction.
Interviewees from all stakeholder groups endorsed using VMHR to provide supplies for wound care, fentanyl test strips, naloxone, and materials to connect individuals to treatment and other services. Dispensing syringes and medications for opioid use disorder were commonly endorsed by health center staff but were more controversial among potential end users. Even within stakeholder groups, views varied with respect to where to locate the machines, but most agreed that the machine should be placed in the highest drug use areas. Across stakeholder groups, interviewees suggested several strategies to introduce and gain community acceptance of VMHR, including community education, one-on-one conversations with community members, and coupling the machine with safe disposal of syringes and information to link individuals to treatment.
Stakeholders were generally receptive to VMHR. The current study findings are consistent with qualitative analyses from outside of the USA and contribute new ideas regarding the anticipated community response and best methods for introducing these machines to a community. With thoughtful planning and design, VMHR could be a feasible and acceptable modality to reduce death and disease transmission associated with the opioid and HIV epidemics in cities like Philadelphia.
Depression and anxiety disorders are significant contributors to burden of disease in young people, highlighting the need to focus preventive efforts early in life. Despite substantial evidence for ...the role of parents in the prevention of adolescent depression and anxiety disorders, there remains a need for translation of this evidence into preventive parenting interventions. To address this gap, we developed a single-session, Web-based, tailored psychoeducation intervention that aims to improve parenting practices known to influence the development of adolescent depression and anxiety disorders.
The aim of this study was to evaluate the short-term effects of the intervention on parenting risk and protective factors and symptoms of depression and anxiety in adolescent participants.
We conducted a single-blind, parallel group, superiority randomized controlled trial comparing the intervention with a 3-month waitlist control. The intervention is fully automated and consists of two components: (1) completion of an online self-assessment of current parenting practices against evidence-based parenting recommendations for the prevention of adolescent depression and anxiety disorders and (2) an individually tailored feedback report highlighting each parent’s strengths and areas for improvement based on responses to the self-assessment. A community sample of 349 parents, together with 327 adolescents (aged 12-15 years), were randomized to either the intervention or waitlist control condition. Parents and adolescents completed online self-reported assessments of parenting and adolescent symptoms of depression and anxiety at baseline, 1-month (parent-report of parenting only), and 3-month follow-up.
Compared with controls, intervention group parents showed significantly greater improvement in parenting risk and protective factors from baseline to 1-month and 3-month follow-up (F
=16.36, P<.001), with a small to medium effect size at 3-month follow-up (d=0.33). There were no significant effects of the intervention on adolescent-report of parenting or symptoms of depression or anxiety in the adolescents (all P>.05).
Findings suggest that a single-session, individually tailored, Web-based parenting intervention can improve parenting factors that are known to influence the development of depression and anxiety in adolescents. However, our results do not support the effectiveness of the intervention in improving adolescent depression or anxiety symptoms in the short-term. Long-term studies are required to adequately assess the relationship between improving parenting factors and adolescent depression and anxiety outcomes. Nonetheless, this is a promising avenue for the translation of research into a low-cost, sustainable, universal prevention approach.
Australian New Zealand Clinical Trials Registry: ACTRN12615000247572; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12615000247572 (Archived by WebCite at http://www.webcitation.org/6v1ha19XG)
Burgeoning research suggests that parents can reduce the risk of anxiety and depression in their adolescents and that parental self‐efficacy (PSE) may be related to parental risk and protective ...factors for these disorders. As there are currently no measures available to assess PSE in relation to parenting behaviors that may reduce adolescent risk for depression and anxiety, we developed and validated a measure of PSE, the Parental Self‐Efficacy Scale (PSES). Using a sample of 359 parents and 332 adolescents (aged 12–15), the PSES was found to have high reliability, confirmatory factor analysis supported its validity, and most of the hypothesized relationships between the PSES and other measures of parenting practices and adolescent depressive and anxiety symptoms were supported.
Abstract
Background
In response to the COVID-19 pandemic, we launched the Penn Medicine Coping First Aid program to provide psychosocial supports to our health system community. Our approach ...leveraged lay health worker volunteers trained in principles of Psychological First Aid to deliver coaching services through a centralized virtual platform.
Methods
We emailed all (
n
= 408) first year housestaff (i.e., residents and fellows) with an invitation to schedule a session with a resilience coach. We compared the mental health concerns, symptoms, and Psychological First Aid techniques recorded in (
n
= 67) first year housestaff sessions with (
n
= 91) sessions of other employees in the health system.
Results
Between June and November 2020, forty-six first year housestaff attended at least one resilience coaching session. First year housestaff most commonly presented with feelings of anxiety and sadness and shared concerns related to the availability of social support. Resilience coaches most frequently provided practical assistance and ensured safety and comfort to first year housestaff. First year housestaff reported fewer physical or mental health symptoms and held shorter sessions with resilience coaches than non-housestaff.
Conclusions
This work offers insights on how to address psychosocial functioning through low-intensity interventions delivered by lay personnel. More research is needed to understand the efficacy of this program and how best to engage housestaff in wellness and resilience programs throughout training, both during and beyond COVID-19.
We present a population study of the star formation history of 1244 Type 2 active galactic nuclei (AGN) host galaxies, compared to 6107 inactive galaxies. A Bayesian method is used to determine ...individual galaxy star formation histories, which are then collated to visualize the distribution for quenching and quenched galaxies within each population. We find evidence for some of the Type 2 AGN host galaxies having undergone a rapid drop in their star formation rate within the last 2 Gyr. AGN feedback is therefore important at least for this population of galaxies. This result is not seen for the quenching and quenched inactive galaxies whose star formation histories are dominated by the effects of downsizing at earlier epochs, a secondary effect for the AGN host galaxies. We show that histories of rapid quenching cannot account fully for the quenching of all the star formation in a galaxy's lifetime across the population of quenched AGN host galaxies, and that histories of slower quenching, attributed to secular (non-violent) evolution, are also key in their evolution. This is in agreement with recent results showing that both merger-driven and non-merger processes are contributing to the co-evolution of galaxies and supermassive black holes. The availability of gas in the reservoirs of a galaxy, and its ability to be replenished, appear to be the key drivers behind this co-evolution.
We compute black hole masses and bolometric luminosities for 57 active galactic nuclei (AGNs) in the redshift range 1.25 < or =, slant z < or =, slant 2.67, selected from the GOODS-South deep ...multi-wavelength survey field via their X-ray emission. We determine host galaxy morphological parameters by separating the galaxies from their central point sources in deep Hubble Space Telescope images, and host stellar masses and colors by multi-wavelength spectral energy distribution fitting. Of GOODS AGNs at these redshifts, 90% have detected rest-frame optical nuclear point sources; bolometric luminosities range from 2 x 10 super(43) to 2 x 10 super(46) erg s super(-1). The black holes are growing at a range of accretion rates, with gap50% of the sample having L/L sub(Edd) < 0.1. Of the host galaxies, 70% have stellar masses M sub(*) > 10 super(10) M sub(middot in circle), with a range of colors suggesting a complex star formation history. We find no evolution of AGN bolometric luminosity within the sample, and no correlation between AGN bolometric luminosity and host stellar mass, color, or morphology. Fully half the sample of host galaxies are disk-dominated, with another 25% having strong disk components. Fewer than 15% of the systems appear to be at some stage of a major merger. These moderate-luminosity AGN hosts are therefore inconsistent with a dynamical history dominated by mergers strong enough to destroy disks, indicating that minor mergers or secular processes dominate the coevolution of galaxies and their central black holes at z ~ 2.
The harms of opioid use disorder (OUD) and HIV infection disproportionately impact marginalized populations, especially people experiencing homelessness and people who inject drugs (PWID). Mobile OUD ...service delivery models are emerging to increase access and reduce barriers to OUD care. While there is growing interest in these models, there is limited research about the services they provide, how they operate, and what barriers they face. We characterize the capacity, barriers, and sustainment of mobile OUD care services in a large city with a high incidence of OUD and HIV.
From May to August 2022, we conducted semi-structured interviews with leadership from all seven mobile OUD care units (MOCU) providing a medication for OUD or other substance use disorder services in Philadelphia. We surveyed leaders about their unit's services, staffing, operating location, funding sources, and linkages to care. Leaders were asked to describe their clinical approach, treatment process, and the barriers and facilitators to their operations. Interview recordings were coded using rapid qualitative analysis.
MOCUs are run by small, multidisciplinary teams, typically composed of a clinician, one or two case managers, and a peer recovery specialist or outreach worker. MOCUs provide a range of services, including medications for OUD, wound care, medical services, case management, and screening for infectious diseases. No units provide methadone, but all units provide naloxone, six write prescriptions for buprenorphine, and one unit dispenses buprenorphine. The most frequently reported barriers include practical challenges of working on a MOCU (e.g. lack of space, safety), lack of community support, and patients with substantial medical and psychosocial needs. Interviewees reported concerns about funding and specifically as it relates to providing their staff with adequate pay. The most frequently reported facilitators include positive relationships with the community, collaboration with other entities (e.g. local nonprofits, the police department, universities), and having non-clinical staff (e.g. outreach workers, peer recovery specialists) on the unit.
MOCUs provide life-saving services and engage marginalized individuals with OUD. These findings highlight the challenges and complexities of caring for PWID and demonstrate a need to strengthen collaborations between MOCU providers and the treatment system. Policymakers should consider programmatic funding for permanent mobile OUD care services.
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