Carbon monoxide (CO) is one of the signaling molecules that are ubiquitous in humans, which involves in the regulation of human physiology and pathology. In this work, the probe
PEC
was designed and ...synthesized based on BODIPY fluorophore that can selectively detect CO through reducing the nitro group to amino group, resulting in a “turn-on” fluorescence response with a simultaneous increase in the concentration of CO. The response is selective over a variety of relevant reactive free radicals, ions, and amino acid species.
PEC
has the advantages of good stability, good water solubility, and obvious changes in fluorescence signals. In addition,
PEC
can be used to detect and track endogenous CO in living cells.
A highly selective and sensitive OFF-ON fluorescent sensor 1, employing the PET mechanism, was designed and synthesized. It could be used to detect Cd2+ ion in aqueous solution and to image Cd2+ ion ...in living cells. The fluorescence intensity significantly enhanced about 195-fold and the quantum yield increased almost 100-fold. Moreover the fluorescence intensity of 1 increased linearly with high sensitivity (0−1 μM) toward Cd2+.
On the basis of tricabocyanine, two near-infrared fluorescent sensors CYP-1 and CYP-2 have been designed and synthesized. Both of them can selectively and sensitively recognize Cd2+ from other metal ...ions, especially the CYP-2, which can distinguish Cd2+ in neutral buffer solution.
Development of simple and selective methods for the detection of hydrazine has attracted much attention, because hydrazine is harmful to human organs and is a probable human carcinogen. As presented ...in this work, two new colorimetric and fluorescent probes (HP1 and HP2) for hydrazine based on dipyrromethene boron difluoride (BODIPY) fluorophore were synthesized and characterized, which showed different reactivity with hydrazine through Gabriel reaction mechanism. In the case of HP1, the hydrazinelysis occurred completely and lead to an enhanced fluorescence that is due to the released N-protecting group. However, the hydrazinelysis of HP2 did not reach its completion, where the additioned hydrazine group caused efficient PET quenching, resulting in a decreased fluorescence. Both probes displayed good sensitivity and selectivity to hydrazine in aqueous medium.
Display omitted
•Two fluorescent probes based on BODIPY fluorophore and Gabriel reaction for hydrazine were developed.•Both fluorescent probes exhibit good sensitivity and selectivity to hydrazine in aqueous medium.•The fluorescent probes showed different reactivity with hydrazine.
Developing fluorescent probes for selective and sensitive detection of hypochlorite has received much attention, because hypochlorite is closely related to human health. In this work, a new ...fluorescent probe based on dipyrromethene boron difluoride (BODIPY) fluorophore using hydrazine as detecting group for hypochlorite was synthesized and fully characterized. The reaction of the probe with sodium hypochlorite is complete within 1 min in phosphate-buffered saline, and the fluorescence of the system significantly enhanced. The probe also exhibits admirable sensitivity and selectivity as well. The results of nuclear magnetic resonance monitoring and high-performance liquid chromatography analysis indicate that the detection process plausibly involves a free radical oxidation mechanism.
▪
•A BODIPY-based probe is developed for detection of hypochlorite.•This probe displays excellent reactivity with sodium hypochlorite.•This probe exhibits high sensitivity and selectivity in PBS buffer solution.
This review summarizes the design principles, preparation methods, optical properties, and the wide applications of fluorescent metallacycles featuring the fluorescence-resonance energy transfer ...behavior.
Display omitted
During past few years, the construction of fluorescent metallacycles featuring the fluorescence-resonance energy transfer behavior has attracted extensive attention due to their diverse applications such as real-time monitoring the dynamics of coordination-driven self-assembly, photoswitching fluorescence-resonance energy transfer, and light-controlled generation of singlet oxygen for cancer therapy. This review focuses on the recent advances on the design principles, preparation methods, optical properties, and the wide applications of fluorescent metallacycles with the FRET property.
A fluorescent sensor for cadmium (CS) based on the BODIPY fluorophore exploiting the PET (Photoinduced Electron Transfer) mechanism was prepared. CS exhibited high selectivity and sensitivity for ...detecting cadmium in aqueous buffer solution. In addition, the complex of CS with cadmium could detect pyrophosphate (PPi) selectively and sensitively.
Display omitted
•An organoruthenium-functionalized chrysanthemum-like mesoporous silica is constructed.•This heterogeneous catalyst boosts aqueous asymmetric transfer hydrogenation with extensive ...substrates.•Uniform distribution of the active site-isolated chiral organoruthenium results in a high recyclability.•We offer a general approach to immobilize a homogeneous complex onto a functionalized mesoporous material.
Exploring functionalized mesoporous silica to achieve enhanced catalytic activity and enantioselectivity in heterogeneous asymmetric catalysis presents a significant challenge that is critical for understanding the function of support and controlling chiral complexation behavior. In this contribution, by cooperative assembly of chiral 4-(trimethoxysilyl)ethyl)phenylsulfonyl-1,2-diphenylethylene-diamine and tetraethoxysilane followed by complexation with organoruthenium complex, we report a unique three-dimensional chiral organoruthenium-functionalized chrysanthemum-like mesoporous silica (CMS). As demonstrated in the studies, taking advantage of the active site-isolated chiral organoruthenium catalytic nature, this heterogeneous catalyst ArRuTsDPEN-CMS (Ar=hexamethylbenzene, TsDPEN=4-methylphenylsulfonyl-1,2-diphenylethylene-diamine) displays enhanced catalytic activity and enantioselectivity in aqueous asymmetric transfer hydrogenation with extensive substrates. Furthermore, this heterogeneous catalyst can be conveniently recovered and reused at least 10 times without loss of its catalytic efficiency. These features render this catalyst particularly attractive in practice of organic synthesis in an environmentally friendly manner. Also, this outcome from the study clearly shows that the strategy described here offers a general approach to immobilization of chiral ligand-derived silane onto a functionalized mesoporous material with significant improving catalytic activity.
A series of triphenylamine-based fluorescent compounds displaying acid-induced tunable white light emission were developed.
Display omitted
A series of triphenylamine (TPA) derivatives with various ...substituent groups were prepared and showed different absorption and fluorescence characteristics due to the substituent effect. On account of the existence of pyridine units, these TPA derivatives exhibited acid-induced tunable multicolor fluorescence emission including white light emission. In addition, acid-induced fluorescence regulation of these compounds has been also realized in the solid state, which enable them to be successfully constructed the stimuli-responsive fluorescent films and fluorescent inks for inkjet printing.
The design of a smart heterogeneous catalyst for controllable reaction switching is highly desirable in asymmetric catalysis. In this work, by taking advantage of the thermoresponsive behavior of a ...water-soluble polymer coating and the confined feature of silica nanoparticles, we have constructed a silica material with chiral rhodium/diamine functionality on SiO2 nanospheres coated with a water-soluble thermoresponsive polymer. The solid-state 13C NMR spectrum of the product demonstrated well-defined single-site chiral rhodium active centers within the thermoresponsive polymer, and scanning electron microscopy and transmission electron microscopy revealed its uniformly dispersed morphology. As a smart heterogeneous catalyst, it enables catalyst-based temperature-controlled reaction switching in the enantioselective tandem reduction–lactonization of ethyl 2-acylarylcarboxylates in water. At 40 °C, the catalyst promotes highly enantioselective tandem reduction–lactonization by adopting the extended form of the thermoresponsive polymer coating, whereas at 15 °C the reaction is terminated and the heterogeneous catalyst can be recycled because of its closed form. This feature endows this catalyst with high efficiency and recyclability for the synthesis of chiral phthalides in an environmentally friendly medium.
