Although antiretroviral therapy has limited efficiency, patients should take multiple drugs in combination in prescribed time for lifelong and they should also require specific food and fluid ...restriction. Due to these and other factors patients may discontinue their medication and therefore face significant challenges in adherence.
To assess factors associated with non-adherence among people living with HIV receiving the antiretroviral therapy.
Between July 2011 to January 2012, a cross sectional survey was conducted among patients visiting HIV/AIDS unit, Tribhuvan University Teaching Hospital for therapy. After taking informed consent, a pre-structured questionnaire was filled up and data were entered into SPSS 11.5 system and analyzed.
Of the 100 studied subjects, 61 (61.0%) were male and 39 (39%) were female. Adherence was found to be 79%. The major barrier to adherence was reported to be simply forgetfulness (33.3% of those non adherents). Non adherence was significantly associated with types of family (X² value, 7.11), smoking (X² value, 5.44) and alcoholic habit (X² value, 5.69) but not with gender (X² value, 2.57). Besides this, poor economic status, and attendance to religious ceremony were reported to be major obstacles to adherence.
Adherence at this center was found to be only satisfactory. Forgetfulness was reported to be the major cause of non adherence. Persons living in joint family and those with alcoholic and /or smoking habit were more likely to miss the pills. It can be recommended that effective counseling, moral/financial support for HIV/AIDS patients may increase their adherence.
Twelve broadband magnetotelluric (MT) soundings were performed across the Himalaya of Central Nepal in 1996 in order to determine the electrical structure of the crust and its relation to geological ...structures and active tectonics. The MT impedance tensors were obtained for frequencies between 0.001 and 500 Hz. The 2‐D section, derived from joint inversion of TE‐ and TM mode after RRI and Groom/Bailey decomposition, shows high conductivity in the foreland basin (∼30 Ω.m) that contrasts with the resistive Indian basement (>300 Ω.m) and Lesser Himalaya (>1000 Ω.m). In addition, our MT sounding reveals a major conductive feature beneath the front of the Higher Himalaya, also characterized by intense microseismic activity, and the position of a mid‐crustal ramp along the major active thrust fault (MHT). This high conductivity zone probably reflects metamorphic fluids, released during underthrusting of the Indian basement and pervading well connected microcracks induced by interseismic stress build‐up, or distributed brittle deformation around the ramp.
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