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  • Aging across the tree of li... Aging across the tree of life: The importance of a comparative perspective for the use of animal models in aging
    Cohen, Alan A. Biochimica et biophysica acta. Molecular basis of disease, September 2018, 2018-Sep, 2018-09-00, 20180901, Letnik: 1864, Številka: 9
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    Use of model organisms in aging research is problematic because our ability to extrapolate across the tree of life is not clear. On one hand, there are conserved pathways that regulate lifespan in ...
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  • Complex systems dynamics in... Complex systems dynamics in aging: new evidence, continuing questions
    Cohen, Alan A. Biogerontology (Dordrecht), 02/2016, Letnik: 17, Številka: 1
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    There have long been suggestions that aging is tightly linked to the complex dynamics of the physiological systems that maintain homeostasis, and in particular to dysregulation of regulatory networks ...
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  • Immunosenescence and Inflam... Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?
    Fulop, Tamas; Larbi, Anis; Dupuis, Gilles ... Frontiers in immunology, 01/2018, Letnik: 8
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    The immune system is the most important protective physiological system of the organism. It has many connections with other systems and is, in fact, often considered as part of the larger ...
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  • The physical frailty syndro... The physical frailty syndrome as a transition from homeostatic symphony to cacophony
    Fried, Linda P; Cohen, Alan A; Xue, Qian-Li ... Nature aging, 01/2021, Letnik: 1, Številka: 1
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    Frailty in aging marks a state of decreased reserves resulting in increased vulnerability to adverse outcomes when exposed to stressors. This Perspective synthesizes the evidence on the aging-related ...
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  • What does carotenoid-depend... What does carotenoid-dependent coloration tell? Plasma carotenoid level signals immunocompetence and oxidative stress state in birds-A meta-analysis
    Simons, Mirre J P; Cohen, Alan A; Verhulst, Simon PloS one, 08/2012, Letnik: 7, Številka: 8
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    Mechanisms maintaining honesty of sexual signals are far from resolved, limiting our understanding of sexual selection and potential important parts of physiology. Carotenoid pigmented visual signals ...
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  • Adult and child malaria mor... Adult and child malaria mortality in India: a nationally representative mortality survey
    Dhingra, Neeraj, MD; Jha, Prabhat, Prof; Sharma, Vinod P, DPhil ... The Lancet, 11/2010, Letnik: 376, Številka: 9754
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    Summary Background National malaria death rates are difficult to assess because reliably diagnosed malaria is likely to be cured, and deaths in the community from undiagnosed malaria could be ...
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  • Detection of a novel, integ... Detection of a novel, integrative aging process suggests complex physiological integration
    Cohen, Alan A; Milot, Emmanuel; Li, Qing ... PloS one, 03/2015, Letnik: 10, Številka: 3
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    Many studies of aging examine biomarkers one at a time, but complex systems theory and network theory suggest that interpretations of individual markers may be context-dependent. Here, we attempted ...
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  • Eleven Telomere, Epigenetic... Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing?
    Belsky, Daniel W; Moffitt, Terrie E; Cohen, Alan A ... American journal of epidemiology, 06/2018, Letnik: 187, Številka: 6
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    Abstract The geroscience hypothesis posits that therapies to slow biological processes of aging can prevent disease and extend healthy years of life. To test such “geroprotective” therapies in ...
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  • What if there’s no such thi... What if there’s no such thing as “aging”?
    Cohen, Alan A.; Legault, Véronique; Fülöp, Tamàs Mechanisms of ageing and development, December 2020, 2020-12-00, 20201201, Letnik: 192
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    •Our mental categories tend to correspond to our linguistic categories.•We argue there is no biological phenomenon that corresponds to the word “aging”.•We show how the concept of “aging” misleads us ...
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