AIM： To optimize the preoperative diagnosis and surgical management of adult intussusception （AI）.
METHODS： A retrospective review of the clinical features, diagnosis, management and pathology 41 ...adult patients with postoperative diagnoses of intussusception was conducted.
RESULTS： Forty-one patients with 44 intussusceptions were operated on, 24.4% had acute symptoms, 24.4% had subacute symptoms, and 51.2% had chronic symptoms. 70.7% of the patients presented with intestinal obstruction. There were 20 enteric, 15 ileocolic, eight colocolonic and one sigmoidorectal intussusceptions. 65.9% of intussusceptions were diagnosed preoperatively using a computed tomography （CT） scan （90.5% accurate） and ultrasonography （60.0% accurate, rising to 91.7% for patients who had a palpable abdominal mass）. Coloscopy located the occupying lesions of the lead point of ileocolic, colocolonic and sigmoidorectal intussusceptions. Four intussusceptions in three patients were simply reduced. Twenty-one patients underwent resection after primary reduction. There was no mortality and anastomosis leakage perioperatively. Except for one patient with multiple small bowel adenomas, which recurred 5 mo after surgery, no patients were recurrent within 6 mo.Pathologically, 54.5% of the intussusceptions had a tumor, of which 27.3% were malignant. 9.1% comprised nontumorous polyps. Four intussusceptions had a gastrojejunostomy with intestinal intubation, and four intussusceptions had no organic lesion.
CONCLUSION： CT is the most effective and accurate diagnostic technique. Colonoscopy can detect most lead point lesions of non-enteric intussusceptions. Intestinal intubation should be avoided.
Background：Globally,the proportion of child deaths that occur in the neonatal period remains a high level of 37-41%.Differences of cause in neonate death exist in different regions as well as in ...different economic development countries.The specific aim of this study was to investigate the causes,characteristics,and differences of death in neonates during hospitalization in the tertiary Neonatal Intensive Care Unit （NICU） of China.Methods：All the dead neonates admitted to 26 NICUs were included between January 1,2011,and December 31,2011.All the data were collected retrospectively from clinical records by a designed questionnaire.Data collected from each NICU were delivered to the leading institution where the results were analyzed.Results：A total of 744 newborns died during the l-year survey,accounting for 1.2% of all the neonates admitted to 26 NICUs and 37.6% of all the deaths in children under 5 years of age in these hospitals.Preterm neonate death accounted for 59.3% of all the death.The leading causes of death in preterm and term infants were pulmonary disease and infection,respectively.In early neonate period,pulmonary diseases （56.5%） occupied the largest proportion ofpreterm deaths while infection （27%） and neurologic diseases （22%） were the two main causes of term deaths.In late neonate period,infection was the leading cause of both preterm and term neonate deaths.About two-thirds of neonate death occurred after medical care withdrawal.Of the cases who might survive if receiving continuing treatment,parents＇ concern about the long-term outcomes was the main reason of medical care withdrawal.Conclusions：Neonate death still accounts for a high proportion of all the deaths in children under 5 years of age.Our study showed the majority of neonate death occurred in preterm infants.Cause of death varied with the age of death and gestational age.Accurate and prompt evaluation of the long-term outcomes should be carried out to guide the critical decision.
A Fair E-Cash Payment Scheme Based on Credit Wang, Shao-Bin; Hong, Fan; Cui, Guo-Hua
Wuhan University journal of natural sciences,
2006, 2006-1-00, 20060101, Letnik:
11, Številka:
1
Journal Article
Recenzirano
A new fair e-eash payment scheme based on credit is present in this paper. In the scheme, an overdraft credit certificate is issued to user by hank. Using the overdraft credit certificate, user can ...produce e-cash himself to pay in exchanges. Merchant can verify the e-cash received from user. Bank can make a fair dis pute resolution when there is a dissension between user and merchant. It can avoid ＇the problem of partition e-cash for changes, prevent from reusing e-cash and fa- king e-cash, It. fits justice, anonymity, non deny and impartiality.
Aim： 3-Methyl-6-chloro-7,8-hydroxy-1-（3-methylphenyl）-2,3,4,5-tetrahydro-1H-3-benzazepine （SKF83959） have been shown to affect several types of voltage-dependent channels in hippocampal pyramidal ...neurons. The aim of this study was to determine how modulation of a individual type of the channels by SKF83959 contributes to the overall excitability of CA1 pyramidal neurons during either direct current injections or synaptic activation.
Methods： Rat hippocampal slices were prepared. The kinetics of voltage-dependent Na^＋ channels and neuronal excitability and depolarization block in CA1 pyramidal neurons were examined using whole-cell recording. A realistic mathematical model of hippocampal CA1 pyramidal neuron was used to simulate the effects of SKF83959 on neuronal excitability.
Results： SKF83959 （50 μmol/L） shifted the inactivation curve of Na^＋ current by 10.3 mV but had no effect on the activation curve in CA1 pyramidal neurons. The effects of SKF83959 on passive membrane properties, including a decreased input resistance and depolarized resting potential, predicted by our simulations were in agreement with the experimental data. The simulations showed that decreased excitability of the soma by SKF83959 （examined with current injection at the soma） was only observed when the membrane potential was compensated to the control levels, whereas the decreased dendritic excitability （examined with current injection at the dendrite） was found even without membrane potential compensation, which led to a decreased number of action potentials initiated at the soma. Moreover, SKF83959 significantly facilitated depolarization block in CA1 pyramidal neurons. SKF83959 decreased EPSP temporal summation and, of physiologically greater relevance, the synaptic-driven firing frequency.
Conclusion： SKF83959 decreased the excitability of CA1 pyramidal neurons even though the drug caused the membrane potential depolarization. The results may reveal a partial mechanism for the drug’s anti-Parkinsonian effects and may also suggest that SKF83959 has a potential antiepileptic effect.
Although studies on the balance between yield and quality of japonica soft super rice are limited, they are crucial for super rice cultivation. In order to investigate the effects of nitrogen ...application rate on grain yield and rice quality, two japonica soft super rice varieties, Nanjing 9108 （NJ 9108） and Nanjing 5055 （NJ 5055）, were used under seven N levels with the application rates of 0, 150, 187.5,225, 262.5, 300, and 337.5 kg ha^-1. With the increasing nitrogen application level, grain yield of both varieties first increased and then decreased. The highest yield was obtained at 300 kg ha^-1. The milling quality and protein content increased, while the appearance quality, amylose content, gel consistency, cooking/eating quality, and rice flour viscosity decreased. Milling was significantly negatively related with the eating/cooking quality whereas the appearance was significantly positively related with cooking/eating quality. These results suggest that nitrogen level significantly affects the yield and rice quality of japonica soft super rice. We conclude that the suitable nitrogen application rate for japonica soft super rice, NJ 9108 and NJ 5055, is 270 kg ha^-1, under which they obtain high yield as well as superior eating/cooking quality.
Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic.
(PS), a natural plant used in traditional Chinese medicine, has various functions ...associated with a number of its components. There are many compositions in PS including polysaccharides, steroids, anthraquinone, alkaloids, cardiac glycosides, lignin, vitamins, various acids, and so on. Of these, polysaccharides play a significant role in PS-based therapeutics. This article summarizes
polysaccharides (PSP) have many pharmacological applications and biological activities, such as their antioxidant activity, anti-aging activity, an anti-fatigue effect, immunity enhancement effect, antibacterial effect, anti-inflammatory effect, hypolipidemic and antiatherosclerotic effects, anti-osteoporosis effect, liver protection, treatment of diabetes mellitus (DM), anti-cancer effect, and may help prevent Alzheimer's disease, and so on. This review summarized the extraction method, purification method, compositions, pharmacological applications, biological activities, biosynthesis, and prospects of PSP, providing a basis for further study of PS and PSP.
Objective： To observe the therapeutic efficacy of Fu＇s subcutaneous needling （FSN） with laser for postherpetic neuralgia and analyze its action mechanism. Methods： A total of 102 cases with ...postherpetic neuralgia were randomly allocated into a treatment group and a control group, 51 in each group. FSN with laser was used for patients in the treatment group, whereas electroacupuncture was used for patients in the control group. After 6 months of treatment, the total effective rates, action time and cure courses in recovery cases were compared between the two groups. Three months after the treatment was completed, a follow-up was done to compare relapse rates between the two groups. Results： The recovery and total effective rates in the treatment group were 56.9% and 94.1% respectively, versus 35.3% and 68.6% in the control group, showing statistical differences （P〈0.05）; the action time and cure courses in the observation group were significantly shorter than those in the control group （P〈0.05）; the relapse rate in the treatment group was 6.9%, versus 44.4% in the control group, showing a statistical difference （P〈0.05）. Conclusion： FSN with laser can obtain better effect for postherpetic neuralgia than electroacupuncture and pose lower relapse risks.
Cellular uptake and exocytosis of SWCNTs are fundamental processes determining their intracellular concentration and effects. Despite the great potential of acid-oxidized SWCNTs in biomedical field, ...understanding of the influencing factors on these processes needs to be deepened. Here, we quantitatively investigated uptake and exocytosis of SWCNTs in three lengths-630 (±171) nm (L-SWCNTs), 390 (±50) nm (M-SWCNTs), and 195 (±63) nm (S-MWCNTs) in macrophages. The results showed that the cellular accumulation of SWCNTs was a length-independent process and non-monotonic in time, with the most SWCNTs (3950 fg/cell) accumulated at 8 h and then intracellular SWCNTs dropped obviously with time. The uptake rate of SWCNTs decreased with increasing concentration, suggesting that intracellular SWCNTs accumulation is a saturable process. After refreshing culture medium, we found increasing SWCNTs in supernatant and decreasing intracellular SWCNTs over time, confirming the exocytosis occurred. Selective inhibition of endocytosis pathways showed that the internalization of SWCNTs involves several pathways, in the order of macropinocytosis> caveolae-mediated endocytosis> clathrin-dependent endocytosis. Intriguingly, clathrin-mediated endocytosis is relatively important for internalizing shorter SWCNTs. The dynamic processes of SWCNTs uptake and exocytosis and the mechanisms revealed by this study may render a better understanding on SWCNT toxicity and facilitate the design of CNT products with mitigated toxicity and desired functions.
The nanostructures based on polymers have attracted much research interest because of their rich morphologies, unique properties and potential applications in various fields. In particular, helical ...nanostructures have been research hotspots in recent years. In this work, composite non-helical and helical nanowire arrays of atactic poly(2-vinylpyridine) (P2VP), and block copolymers polystyrene-block-poly(2-vinylpyridine) (PS-b-P2VP) were fabricated successfully with inorganic species such as HAuCl4 through a liquid/liquid interfacial adsorption and self-assembly approach without addition of any chiral inducers. The formation process of the helical nanowires of P2VP includes the following steps, i.e. adsorption of the polymer molecules and HAuCl4 at the interface, the following protonation of pyridine groups, straightening of the P2VP chains by mutual repulsion between the protonated pyridine groups, aggregation of the P2VP chains due to the hydrophobic interactions between the backbones, and ordered organization of the pyridine groups through π-π interactions. The helical nanowires of PS-b-P2VP are worm-like micelles with a PS core and a P2VP shell, which are formed through the self-assembly of the block copolymer molecules with HAuCl4 within the interfacial phase with the help of hydrophobic interaction between the PS blocks and orderly stacking of the P2VP blocks. The different formation mechanisms reflected the effects of molecular structure on the self-assembly of polymers. In addition, the formed nanowires further self-organize into ordered arrays due to the increasing interfacial pressure during the generation of the nanowires. The results of this study expand the scope of research on polymer self-assembly and the application of liquid/liquid interfacial self-assembly techniques to acquire highly ordered supramolecular nanostructures.
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•PS and PS-b-P2VP self-assembled into helical nanowires with chloroauric acid.•The nanowires formed in the liquid/liquid interfacial phase.•These nanowires further organized into parallel arrays.•The PS nanowires result from chain straightening, aggregation and ordered packing.•The PS-b-P2VP nanowires are actually worm-like micelles.
Benefiting from the large stock of raw materials and the support of policies, China’s biomass utilization get rapid development in recent years. In particular, the Chinese government advocates the ...transformation of energy utilization from coal power to renewable energy power generation, of which biomass power generation will be play an important role. Therefore, it is necessary to get the actual situation of China’s biomass power generation industry at present. The latest storage and distribution of biomass resources data in China is collected and the technological development of biomass power plants in China is described in this paper. The installed capacity and power generation of biomass power generation in China are illustrated since 2012. This paper also counts policies related to biomass power generation since 2006 and analyzes future policy trends. Some recommendations with practical problems are put forward in this paper.
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