MOVIE (multitasking object-oriented visual interactive environment) is the new software system for high performance distributed computing (HDPC), currently in the advanced design and implementation ...stage at Northeast Parallel Architectures Center (NPAC), Syracuse University. MOVIE System is structured as a multiserver network of interpreters of high-level object-oriented programming language MovieScript. MovieScript derives from PostScript and extends it in the C++ syntax based object-oriented interpreted style towards 3D graphics, high performance computing and general purpose high level communication protocol for distributed and MIMD-parallel computing. The authors describe the overall open systems based MOVIE design and itemize currently implemented, developed and planned components of the system.< >
We measured incorporation of 3H-labeled lipid precursors into surfactant-associated and nonsurfactant associated phospholipids in 2- to 7-day primary cultures of rabbit type II alveolar epithelial ...cells, in order to assess the degree to which cells retain metabolic features related to surfactant production in vitro. Unsaturated phosphatidyl choline label increased progressively in type II cell monolayers grown in the continuous presence of 3H-choline, but label in saturated phosphatidyl choline, the surfactant-associated fraction, remained constant after 2 days in culture. Although type II cell cultures could be stimulated to increase saturated phosphatidyl choline production by brief exposure to 8.5 x 10(-5) M palmitic acid, this response proved to be transient. Type II cells synthesized the other major surfactant-associated lipid, phosphatidyl glycerol, from 3H-palmitic acid in vitro, in proportions decreasing from 6.3 per cent of total lipid synthesis in fresh cell isolates to 1.8 per cent in 2-day cultures and 1.4 per cent in 4-day cultures. Aging of the cell cultures was also associated with a proportionate decrease in synthesis of neutral lipids and increases in synthesis of phosphatidyl choline, sphingomyelin, and phosphatidyl inositol, from palmitic acid. We conclude that: (1) isolated type II alveolar cells continue synthesis of surfactant-related lipid species, a major index of differentiated function, for at least 4 days after introduction into cell culture; (2) production of non-surfactant related lipids occupies a progressively larger portion of type II cell lipid synthetic activity during this period, probably reflecting increased synthesis of cell membranes.
Virtual environments will be naturally integrated with high performance computing (HPC) since: (a) advanced grand challenge type simulations will benefit from dynamic virtual environment front-ends, ...and (b) advanced virtual environments will require simulation engines based on high performance computing resources. Such an integration minimally requires interoperability and standardized interfaces between both components. The discussion of these requirements is extended and it is shown how relevant design issues can be elegantly addressed by the multilashing object-oriented visual interactive environment (MOVIE) system, currently under development at North Parllel Architectures Center as an infrastructure layer for dynamic interactive HPC.< >
