The battery energy storage station (BESS) is the current and typical means of smoothing wind- or solar-power generation fluctuations. Such BESS-based hybrid power systems require a suitable control ...strategy that can effectively regulate power output levels and battery state of charge (SOC). This paper presents the results of a wind/photovoltaic (PV)/BESS hybrid power system simulation analysis undertaken to improve the smoothing performance of wind/PV/BESS hybrid power generation and the effectiveness of battery SOC control. A smoothing control method for reducing wind/PV hybrid output power fluctuations and regulating battery SOC under the typical conditions is proposed. A novel real-time BESS-based power allocation method also is proposed. The effectiveness of these methods was verified using MATLAB/SIMULINK software.
Flexible metal–organic frameworks (MOFs) receive much attention owing to their attractive properties that originate from their flexibility and dynamic behavior, and show great potential applications ...in many fields. Here, recent progress in the discovery, understanding, and property investigations of flexible MOFs are reviewed, and the examples of their potential applications in storage and separation, sensing, and guest capture and release are presented to highlight the developing trends in flexible MOFs.
Flexible metal–organic frameworks are widely investigated as functional materials based on their remarkable properties, and potential applications of these materials are found in many fields. The most recent advances in the discovery, understanding and property investigations are reviewed, and new trends for their applications are highlighted.
To investigate the clinical and imaging characteristics of computed tomography (CT) in novel coronavirus pneumonia (NCP) caused by SARS-CoV-2.
A retrospective analysis was performed on the imaging ...findings of patients confirmed with COVID-19 pneumonia who had chest CT scanning and treatment after disease onset. The clinical and imaging data were analyzed.
Fifty patients were enrolled, including mild type in nine, common in 28, severe in 10 and critically severe in the rest three. Mild patients (29 years) were significantly (P<0.03) younger than either common (44.5 years) or severe (54.7) and critically severe (65.7 years) patients, and common patients were also significantly (P<0.03) younger than severe and critically severe patients. Mild patients had low to moderate fever (<39.1 °C), 49 (98%) patients had normal or slightly reduced leukocyte count, 14 (28%) had decreased counts of lymphocytes, and 26 (52%) patients had increased C-reactive protein. Nine mild patients were negative in CT imaging. For all the other types of NCP, the lesion was in the right upper lobe in 30 cases, right middle lobe in 22, right lower lobe in 39, left upper lobe in 33 and left lower lobe in 36. The lesion was primarily located in the peripheral area under the pleura with possible extension towards the pulmonary hilum. Symmetrical lesions were seen in 26 cases and asymmetrical in 15. The density of lesion was mostly uneven with ground glass opacity as the primary presentation accompanied by partial consolidation and fibrosis.
CT imaging presentations of NCP are mostly patchy ground glass opacities in the peripheral areas under the pleura with partial consolidation which will be absorbed with formation of fibrotic stripes if improved. CT scanning provides important bases for early diagnosis and treatment of NCP.
Silver chalcogenolate cluster assembled materials (SCAMs) are a category of promising light‐emitting materials the luminescence of which can be modulated by variation of their building blocks ...(cluster nodes and organic linkers). The transformation of a singly emissive Ag12(SBut)8(CF3COO)4(bpy)4n (Ag12bpy, bpy=4,4′‐bipyridine) into a dual‐emissive (Ag12(SBut)6(CF3COO)6(bpy)3)n (Ag12bpy‐2) via cluster‐node isomerization, the critical importance of which was highlighted in dictating the photoluminescence properties of SCAMs. Moreover, the newly obtained Ag12bpy‐2 served to construct visual thermochromic Ag12bpy‐2/NH2 by a mixed‐linker synthesis, together with dichromatic core–shell Ag12bpy‐2@Ag12bpy‐NH2‐2 via solvent‐assisted linker exchange. This work provides insight into the significance of metal arrangement on physical properties of nanoclusters.
Tandem varying of Ag cluster structure and tuning mixed linkers in a stepwise fashion are used to achieve dual‐emitting homogeneous and core–shell silver chalcogenolate cluster assembled materials. The arrangements of silver in the cluster are demonstrated to play a fundamentally important role in luminescence.
Long non‐coding RNAs (lncRNAs) serve critical roles in the pathogenesis of various cancers, including lung adenocarcinoma (LUAD). Herein, in this study, we aimed to investigate the biological and ...clinical significance of lncRNA DiGeorge syndrome critical region gene 5 (DGCR5) in LUAD. It was observed that DGCR5 was upregulated in LUAD tissues and LUAD cell lines. Inhibition of DGCR5 can prevent LUAD progression via playing anti‐apoptosis roles. Both mRNA expression and protein levels of BCL‐2 were increased by DGCR5 downregulation while reversely BAX was increased. Additionally, a novel microRNA target of DGCR5, hsa‐mir‐22‐3p was identified through bioinformatics search and confirmed by dual‐luciferase reporter system. Gain and loss‐of‐function studies were performed to verify whether DGCR5 exerts its biological functions through regulating hsa‐mir‐22‐3p in vitro. Overexpression of DGCR5 was able to reverse the tumor inhibitory effect of hsa‐mir‐22‐3p mimics. Furthermore, in vivo tests tumor xenografts were established to detect the function of DGCR5 in LUAD tumorigenesis. Downregulated DGCR5 expression was greatly associated with smaller tumor size, implying a favorable prognosis of LUAD patients. Taken these together, DGCR5 could be considered as a prognostic biomarker and therapeutic target in LUAD diagnosis and treatment.
Our findings in LUAD cell lines and xenografts support the use of DGCR5 as an oncogene to promote LUAD development. This is the first reporting of a possible mechanism for a crosstalk between DGCR and hsa‐mir‐22‐3p crosstalk in LUAD. These results suggest DGCR5 as a potential target for LUAD treatment.
Here we report a transcription factor decoy strategy for targeted activation of eight large silent polyketide synthase and non-ribosomal peptide synthetase gene clusters, ranging from 50 to 134 ...kilobases (kb) in multiple streptomycetes, and characterization of a novel oxazole family compound produced by a 98-kb biosynthetic gene cluster. Owing to its simplicity and ease of use, this strategy can be scaled up readily for discovery of natural products in streptomycetes.
Water pollution caused by organic wastewater has become a serious concern worldwide. Fenton oxidation process is one of the most effective and suitable methods for the abatement of organic ...pollutants. However, the process has three obvious shortcomings: the narrow working pH range, the high costs and risks associated with handling, transportation and storage of reagents (H2O2 and catalyst), the significant iron sludge related second pollution. In order to overcome these shortcomings, various optimized Fenton processes have been widely studied. Therefore, a summary of the study status of Fenton optimization processes is necessary to develop a novel and high efficiency organic wastewater treatment method. Based on the optimization perspective, taking shortcomings of Fenton process as a breakthrough, the fundamentals, advantages and disadvantages of single Fenton optimization processes (heterogeneous Fenton, photo-Fenton and electro-Fenton) for organic wastewater treatment were reviewed and the corresponding reaction mechanism diagrams were drawn in this paper. Then, the feasibility and application of the coupled Fenton optimization processes (photoelectro-Fenton, heterogeneous electro-Fenton, heterogeneous photoelectro-Fenton, three-dimensional electro-Fenton) for organic wastewater treatment were discussed in depth. Additionally, the effect of some important operation parameters (pH and catalyst, H2O2, organic pollutants concentration) on the degradation efficiency of organic pollutants was studied to provide guidance for the optimization of operation parameters. Finally, the possible future research directions for optimized Fenton processes were given. The review aims to assist researchers and engineers to gain fundamental understandings and critical view of Fenton process and its optimization processes, and hopefully with the knowledge it could bring new opportunities for the optimization and future development of Fenton process.
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•Review of single Fenton optimization processes for organic wastewater treatment.•Review of coupled Fenton optimization processes for organic wastewater treatment.•Key operational parameters are discussed.•Insights into future research directions for optimized Fenton processes.
We explored whether medical health workers had more psychosocial problems than nonmedical health workers during the COVID-19 outbreak.
An online survey was run from February 19 to March 6, 2020; a ...total of 2,182 Chinese subjects participated. Mental health variables were assessed via the Insomnia Severity Index (ISI), the Symptom Check List-revised (SCL-90-R), and the Patient Health Questionnaire-4 (PHQ-4), which included a 2-item anxiety scale and a 2-item depression scale (PHQ-2).
Compared with nonmedical health workers (n = 1,255), medical health workers (n = 927) had a higher prevalence of insomnia (38.4 vs. 30.5%, p < 0.01), anxiety (13.0 vs. 8.5%, p < 0.01), depression (12.2 vs. 9.5%; p< 0.04), somatization (1.6 vs. 0.4%; p < 0.01), and obsessive-compulsive symptoms (5.3 vs. 2.2%; p < 0.01). They also had higher total scores of ISI, GAD-2, PHQ-2, and SCL-90-R obsessive-compulsive symptoms (p ≤ 0.01). Among medical health workers, having organic disease was an independent factor for insomnia, anxiety, depression, somatization, and obsessive-compulsive symptoms (p < 0.05 or 0.01). Living in rural areas, being female, and being at risk of contact with COVID-19 patients were the most common risk factors for insomnia, anxiety, obsessive-compulsive symptoms, and depression (p < 0.01 or 0.05). Among nonmedical health workers, having organic disease was a risk factor for insomnia, depression, and obsessive-compulsive symptoms (p < 0.01 or 0.05).
During the COVID-19 outbreak, medical health workers had psychosocial problems and risk factors for developing them. They were in need of attention and recovery programs.
Proposed reaction processes of SMX biodegradation and nitrogen conversion with different carbon and nitrogen resources. (Stape 1: Baterial growth; Stape 2: Nitrogen conversion; Stape 3: SMX ...biodegradation).
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•The sulfamethoxazole biodegradation efficiency under different carbon and nitrogen source were illustrated.•The agar well diffusion method was proposed to investigate the dependence of bacterium growth on nitrogen sources.•The toxicity of intermediate compounds were assessed during the process of SMX biodegradation.•Nitrogen and carbon balance experiments were conducted with different carbon and nitrogen source.
This study investigated sulfamethoxazole (SMX) biodegradation and nitrogen conversion by Achromobacter sp. JL9 using different carbon and nitrogen sources. Results showed that SMX and sodium acetate could be co-metabolized as carbon sources for bacterial growth and nitrogen conversion with highest removal efficiencies of 82.44%, 80.2%, and 79.45% for NH4+-N, NO3−-N, and SMX, respectively. Strain JL9 was able to utilize SMX as its sole nitrogen source for growth, with an SMX biodegradation efficiency of 63.10%. In addition, carbon and nitrogen balance analyses showed that approximately 35.31% and 63.22% of carbon and nitrogen, respectively, were lost as gaseous products. Finally, medium toxicity gradually decreased during the carbon and nitrogen dependence experiments. This study, thus, suggests that carbon and nitrogen play vital roles in SMX biodegradation and biotoxicity reduction.
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