The purpose of this study is to identify the patterns of the formation, use and development of human resources at a large construction enterprise, as well as the analysis of the main economic ...indicators based on the use of statistical information. In order to achieve this goal the following tasks were solved: theoretical approaches to the term "staff development" were studied; the methods of personnel development, applied to construction plant; the technical and economic indicators of the activity of building enterprise on the basis of statistical information were revealed. The methodological framework is based on the methods of studying systems analysis, comparisons and analogies, economic-mathematical modeling. As a result of the study it is found that the increase of the completed construction directly depends on the quality of personnel, on its development and improvement. The relevance of the study is confirmed by the fact that the position of Russia in the construction world is quite significant. Due to the large-scale construction, Russia is able to ensure a high level of development of its own economy. To do this, it is necessary to increase investment in the development of human resources.
Relevance of developing the equipment for electro-hydraulic treatment of water and its solutions was substantiated. The device that is one of the electro-hydraulic spark gap installation components ...has been developed in order to eliminate the drawbacks of similar devices used. The application field of the device for electro-hydraulic treatment of solutions is crop production in agriculture. Electro-hydraulic treatment can be used to produce fertilizers in conditions of irrigation of greenhouse vegetable crops in personal subsidiary and peasant (farmer) farms. The installation, in addition to the cylindrical tank, contains a voltage source, a high-voltage transformer, an autotransformer, energy storage devices, rectifying cells, start-control devices and means of control and measuring. Electrodes are installed in this device, one of which has a technical scientific novelty. The tip of the negative electrode is hemispherical, which allows increasing the stored energy in the capacitor, to increase it in the discharge channel, increasing the length of the spark discharge in the liquid. The model of the device has been developed in order to substantiate the design parameters and operation modes. The developed electric diagram required for installation, runup and control of technological modes of electro-hydraulic impact on liquid media is shown. Actual model of the device is presented in photo content. The perspectivity of studying the electro-hydraulic effect is determined.
Abstract
The article is devoted to the substantiation of the structural performance of an ultra-high-frequency (UHF) installation of continuous flow action for defrosting and warming up animal ...colostrum. The dielectric parameters of colostrum in the frozen and liquid state were analyzed to determine the generated power and the depth of penetration of electromagnetic waves. For a given generator power, a threshold power that depends on the electric field strength (EF), and taking into account the change in the attenuation coefficient of electromagnetic waves during heating, a theoretical assessment of the optimal volume of raw materials in which animal colostrum is disinfected was carried out. These indicators are consistent with the design parameters of unconventional cavity resonators.
In order to evaluate the initial requirements for a coolant when designing an installation for obtaining the energy of the “water – ice” phase transition, it is necessary to conduct experimental ...studies on the thermophysical and electrophysical parameters of the coolant. The type of chosen coolant determines the power of the developed installation. (Research purpose) Experimental determination of the thermophysical and electrophysical parameters of the coolant when exposed to an electromagnetic field of super-high frequency, with the prospect of using this coolant in the developed installation. (Materials and methods) The authors used water and a saline solution of sodium chloride at a concentration of 1–20 percent as a coolant in the developed experimental installation for obtaining the energy of the “water-ice” phase transition. When exposed to an electromagnetic field of super-high frequency (microwave oven Mystery MMW-2315G) with a power of 800 watts and a magnetron frequency of 2450 megahertz, the treatment time was alternatively set at 30, 60 and 120 seconds. Measurements were taken of freezing temperature, pH of water and solutions, electrical conductivity, and salt concentration. (Results and discussion) It has been found that when a super-high-frequency electromagnetic field affects a sodium chloride solution at a concentration of 20 percent, its freezing temperature decreases from 16.6 degrees Celsius below zero to 18.5 degrees Celsius below zero, for a eutectic solution - from 21.2 degrees Celsius below zero to 25 degrees Celsius below zero, while pH and salt concentration increase, and specific electrical conductivity decreases as well. (Conclusions) The authors have selected an optimal coolant for the developed experimental installation: a saline solution of sodium chloride at a concentration of 20 percent and a freezing temperature of 16.6 degrees Celsius below zero. It is recommended to provide additional capacity for the electrophysical treatment of the coolant. It has been determined that after the super-high frequency electromagnetic treatment, the freezing temperature of the saline solution dropped to 18.5 degrees Celsius below zero.
Abstract Oxidative DNA damage has been proposed as one of the causes of schizophrenia (SZ), and post mortem data indicate a dysregulation of apoptosis in SZ patients. To evaluate apoptosis in vivo we ...quantified the concentration of plasma cell-free DNA ( cfDNA index, determined using fluorescence), the levels of 8-oxodG in cfDNA (immunoassay) and lymphocytes ( FL1-8-oxodG index, flow cytometry) of male patients with acute psychotic disorders: paranoid SZ (total N = 58), schizophreniform (N = 11) and alcohol-induced (N = 14) psychotic disorder, and 30 healthy males. CfDNA in SZ (N = 58) does not change compared with controls. In SZ patients. Elevated levels of 8-oxodG were found in cfDNA (N = 58) and lymphocytes (n = 45). The main sources of cfDNA are dying cells with oxidized DNA. Thus, the cfDNA/FL1-8-oxodG ratio shows the level of apoptosis in damaged cells. Two subgroups were identified among the SZ patients (n = 45). For SZ-1 (31%) and SZ-2 (69%) median values of cfDNA/FL1-8-oxodG index are related as 1:6 (p < 0.0000001). For the patients with other psychotic disorders and healthy controls, cfDNA/FL1-8-oxodG values were within the range of the values in SZ-2 . Thus, apoptosis is impaired in approximately one-third of SZ patients. This leads to an increase in the number of cells with damaged DNA in the patient's body tissues and may be a contributing cause of acute psychotic disorder.
Earlier we studied the copy number variations (CNVs) of ribosomal repeat (rDNA) and the satellite III fragment (1q12) (f-SatIII) in the cells of schizophrenia patients (SZ) and healthy controls (HC). ...In the present study we pursued two main objectives: (1) to confirm the increased rDNA and decreased f-SatIII content in the genomes of enlarged SZ and HC samples and (2) to compare the rDNA and f-SatIII content in the same DNA samples of SZ and HC individuals.
We determined the rDNA CN and f-SatIII content in the genomes of leukocytes of 1770 subjects HC (N = 814) and SZ (N = 956). Non-radioactive quantitative hybridization method (NQH) was applied for analysis of the various combinations of the two repeats sizes in SZ and HC groups.
f-SatIII in human leukocytes (N = 1556) varies between 5.7 and 44.7 pg/ng DNA. RDNA CN varies between 200 and 896 (N = 1770). SZ group significantly differ from the HC group by lower f-SatIII content and by rDNA abundance. The f-SatIII and rDNA CN are not randomly combined in the genome. Higher rDNA CN values are associated with higher f-SatIII index values in SZ and HC. The f-SatIII variation interval in SZ group increases significantly in the subgroup with the high rDNA CN index values (>300 copies).
Schizophrenia patients' genomes contain low number of f-SatIII copies corresponding with a large ribosomal repeats CN. A scheme is proposed to explain the low f-SatIII content in SZ group against the background of high rDNA CN.
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