The capacity for groups to exhibit collective intelligence is an often-cited advantage of group living. Previous studies have shown that social organisms frequently benefit from pooling imperfect ...individual estimates. However, in principle, collective intelligence may also emerge from interactions between individuals, rather than from the enhancement of personal estimates. Here, we reveal that this emergent problem solving is the predominant mechanism by which a mobile animal group responds to complex environmental gradients. Robust collective sensing arises at the group level from individuals modulating their speed in response to local, scalar, measurements of light and through social interaction with others. This distributed sensing requires only rudimentary cognition and thus could be widespread across biological taxa, in addition to being appropriate and cost-effective for robotic agents.
Metformin has been the first-line drug for the treatment of type II diabetes mellitus for decades, being presently the most widely prescribed antihyperglycemic drug. Retrospective studies associate ...the use of metformin with a reduction in cancer incidence and cancer-related death. However, despite extensive research about the molecular effects of metformin in cancer cells, its mode of action remains controversial. The major molecular targets of metformin include complex I of the mitochondrial electron transport chain, adenosine monophosphate (AMP)-activated protein kinase (AMPK), and mechanistic target of rapamycin complex 1 (mTORC1), but AMPK-independent effects of metformin have also been described. Breast cancer is one of the leading causes of cancer-related morbidity and mortality among women worldwide. Several studies have reinforced a link between breast cancer risk and diabetes. Moreover, metformin significantly reduces breast cancer risk, compared to patients who are not using metformin and is independent of diabetes status. In this review, we summarize the current molecular evidence to elucidate metformin’s mode of action against breast cancer cells.
The aims of this study were (1) to map sensory attributes of vanilla ice cream with reduced fat and sugar, and (2) to determine drivers of liking by applying external preference mapping and reveal ...the relationship between descriptive attributes and hedonic judgments using the partial least squares method. Descriptive sensory profiles (n=11) and consumer test (n=117) of 6 samples of vanilla ice cream (3 traditional and 3 with reduced fat and sugar) were determined. The attributes brightness and sweet aftertaste for sample and creaminess (appearance and texture) and sweet aroma contributed positively to the acceptance of ice cream samples. The attributes aeration, powdered milk aroma and flavor, and white chocolate aroma and flavor contributed positively to the acceptance of the ice creams. The attributes hydrogenated fat aroma and flavor were responsible for the lower acceptance of samples. The reduction in fat and sugar did not necessarily cause a decrease in acceptance. The most important factors were selection of the appropriate sweetener system and the use of good quality raw material.
This study reports the photocatalytic degradation of diclofenac by hybrid materials prepared by combination of graphitic carbon nitride (g-C3N4) and titanium-metal organic framework (NH2-MIL-125), in ...different mass proportions (MOF:C3N4 of 25:75, 50:50 and 75:25). The hybrid materials were fully characterized, and their properties compared to those of the individual components, whose presence was confirmed by XRD. The porous structure was the result of the highly microporous character of the MOF and the non-porous one of g-C3N4. The band gap values were very close to that of MOF component. Photoluminescence measurements suggested an increase on the recombination rate associated to the presence of g-C3N4. Photodegradation tests of diclofenac (10 mg·L-1) were performed under UV LED irradiation at 384 nm. The hybrid materials showed higher photocatalytic activity than the individual components, suggesting the occurrence of some synergistic effect. The photocatalyst with a MOF:g-C3N4 ratio of 50:50 yielded the highest conversion rate, allowing complete disappearance of diclofenac in 2 h. Experiments with scavengers showed that superoxide radicals and holes played a major role in the photocatalytic process photodegradation, being that of hydroxyl radicals less significant. From the identification of by-products species, a degradation pathway was proposed for the degradation of diclofenac under the experimental operating conditions.
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•MOF/g-C3N4 materials were synthetized by a straightforward method.•MOF/g-C3N4 hybrid with high photoactivity toward diclofenac oxidation under UV-LED irradiation.•Diclofenac degradation efficiency was related to C3N4/or MOF content.•Degradation pathway for diclofenac was proposed.
Most problems related to contactless energy transfer are usually dealt within the framework of transformer theory, employing equivalent electric circuits as a tool for their analysis. Here, however, ...a physics approach based on the Maxwell equations is followed. Electric and magnetic fields are utilized to evaluate the Poynting vector, which defines the direction and power density carried by the electromagnetic field. The concepts of magnetic voltage and magnetic flux are utilized to define the instantaneous power guided within the magnetic transmitter. Contactless energy transfer requires two separate parts, a transmitter and a receiver circuit. In this paper, we pay attention to the electromagnetic field guided and emitted by the transmitter; internal skin effect (eddy currents losses) is accounted for; electromagnetic energy leaving the transmitter is evaluated using short-dipole antenna theory. This paper does not offer a new practical application of contactless energy transfer. Its scope is rather different; its aim is to provide a fresh look on contactless energy transfer in the context of an electromagnetics framework.
Context.
Proxima Centauri is the closest star to the Sun. This small, low-mass, mid M dwarf is known to host an Earth-mass exoplanet with an orbital period of 11.2 days within the habitable zone, as ...well as a long-period planet candidate with an orbital period of close to 5 yr.
Aims.
We report on the analysis of a large set of observations taken with the ESPRESSO spectrograph at the VLT aimed at a thorough evaluation of the presence of a third low-mass planetary companion, which started emerging during a previous campaign.
Methods.
Radial velocities (RVs) were calculated using both a cross-correlation function (CCF) and a template matching approach. The RV analysis includes a component to model Proxima’s activity using a Gaussian process (GP). We use the CCF’s full width at half maximum to help constrain the GP, and we study other simultaneous observables as activity indicators in order to assess the nature of any potential RV signals.
Results.
We detect a signal at 5.12 ± 0.04 days with a semi-amplitude of 39 ± 7 cm s
−1
. The analysis of subsets of the ESPRESSO data, the activity indicators, and chromatic RVs suggest that this signal is not caused by stellar variability but instead by a planetary companion with a minimum mass of 0.26 ± 0.05
M
⊕
(about twice the mass of Mars) orbiting at 0.029 au from the star. The orbital eccentricity is well constrained and compatible with a circular orbit.
This study aimed to analyze the physical properties of the seeds of Moquiniastrum polymorphum when processed by mini-SAS, X-ray and seed blower systems. The seeds were purchased from Seeds Caiçara, ...located in Penápolis-SP. After purchase, the seed lot was characterized by standard tests. In the X-ray test the seeds were classified according to their internal morphology as filled, unfilled or malformed. The seed blower was set at six opening settings, resulting in light and heavy fractions. The evaluations were performed by weighing the seeds that remained in the blower (heavy fraction) and by the amount of filled seeds indicated by the X-ray test. The germination tests were composed of four replicates of 50 seeds. The mini-SAS was used for external evaluation. It was concluded that the combined use of the seed blower and the X-ray test was efficient for the evaluation and determination of the physical quality of the seeds of M. polymorphum. The seed blower at opening settings 5 resulted in the best lot quality. The external parameters were not able to qualitatively evaluate the seeds of M. polymorphum.
Stellar activity can induce signals in the radial velocities of stars, complicating the detection of orbiting low-mass planets. We present a method to determine the number of planetary signals ...present in radial-velocity datasets of active stars, using only radial-velocity observations. Instead of considering separate fits with different number of planets, we use a birth-death Markov chain Monte Carlo algorithm to infer the posterior distribution for the number of planets in a single run. In a natural way, the marginal distributions for the orbital parameters of all planets are also inferred. This method is applied to HARPS data of CoRoT-7. We confidently recover the orbits of both CoRoT-7b and CoRoT-7c although the data show evidence for the presence of additional signals.
The performance of check-all-that-apply (CATA), projective mapping, sorting and intensity scales was assessed for determining consumer perception of probiotic yogurts, two prototypes added with ...glucose oxidase, a potential oxygen scavenger and 04 commercial brands available in the Brazilian market. Each sensory methodology was tested by administrating the tests to 30 regular consumers of the product. Napping and CATA did not provide adequate discrimination of the samples while better results were noted for sorting and intensity scales, separating the yogurts containing glucose oxidase from the commercial probiotic yogurt. Sensory methodologies using consumer responses present potential options for the characterization of food matrices with multiple sensory sensations, such as probiotic yogurt.
•CATA, sorting, napping and intensity scales to characterize probiotic yogurts•Sorting and intensity scales presented similar results.•Prototype yogurts presented red points, acid taste, bitter taste and viscous.
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