Abstract The configuration of total hip arthroplasty (THA) implants has constantly evolved since they were first introduced. One of the key components of THA design is the diameter of the prosthetic ...femoral head. It has been well established that the risk of dislocation is lower as the head diameter increases. But head diameter impacts other variables beyond joint stability: wear, cam-type impingement, range of motion, restoration of biomechanics, proprioception and groin pain. The introduction of highly cross-linked polyethylene and hard-on-hard bearings has allowed surgeons to implant large-diameter heads that almost completely eliminate the risk of dislocation. But as a result, cup liners have become thinner. With femoral head diameters up to 36 mm, the improvement in joint range of motion, delay in cam-type impingement and reduction in dislocation risk have been clearly demonstrated. Conversely, large-diameter heads do not provide any additional improvements. If an “ecologically sound” approach to hip replacement is embraced (e.g. keeping the native femoral head diameter), hip resurfacing with a metal-on-metal bearing must be carried out. The reliability of large-diameter femoral heads in the longer term is questionable. Large-diameter ceramic-on-ceramic bearings may be plagued by the same problems as metal-on-metal bearings: groin pain, squeaking, increased stiffness, irregular lubrication, acetabular loosening and notable friction at the Morse taper. These possibilities require us to be extra careful when using femoral heads with a diameter greater than 36 mm.
Context.
Clouds are ubiquitous in exoplanet atmospheres and they represent a challenge for the model interpretation of their spectra. When generating a large number of model spectra, complex cloud ...models often prove too costly numerically, whereas more efficient models may be overly simplified.
Aims.
We aim to constrain the atmospheric properties of the directly imaged planet HR 8799e with a free retrieval approach.
Methods.
We used our radiative transfer code petitRADTRANS for generating the spectra, which we coupled to the PyMultiNest tool. We added the effect of multiple scattering which is important for treating clouds. Two cloud model parameterizations are tested: the first incorporates the mixing and settling of condensates, the second simply parameterizes the functional form of the opacity.
Results.
In mock retrievals, using an inadequate cloud model may result in atmospheres that are more isothermal and less cloudy than the input. Applying our framework on observations of HR 8799e made with the GPI, SPHERE, and GRAVITY, we find a cloudy atmosphere governed by disequilibrium chemistry, confirming previous analyses. We retrieve that C/O = 0.60
−0.08
+0.07
. Other models have not yet produced a well constrained C/O value for this planet. The retrieved C/O values of both cloud models are consistent, while leading to different atmospheric structures: either cloudy or more isothermal and less cloudy. Fitting the observations with the self-consistent Exo-REM model leads to comparable results, without constraining C/O.
Conclusions.
With data from the most sensitive instruments, retrieval analyses of directly imaged planets are possible. The inferred C/O ratio of HR 8799e is independent of the cloud model and thus appears to be a robust. This C/O is consistent with stellar, which could indicate that the HR 8799e formed outside the CO
2
or CO iceline. As it is the innermost planet of the system, this constraint could apply to all HR 8799 planets.
Warm or massive gas giant planets, brown dwarfs, and debris disks around nearby stars are now routinely observed by dedicated high-contrast imaging instruments that are mounted on large, ground-based ...observatories. These facilities include extreme adaptive optics (ExAO) and state-of-the-art coronagraphy to achieve unprecedented sensitivities for exoplanet detection and their spectral characterization. However, low spatial frequency differential aberrations between the ExAO sensing path and the science path represent critical limitations for the detection of giant planets with a contrast lower than a few 10 super(-6) at very small separations (<0.3'') from their host star. In our previous work, we proposed a wavefront sensor based on Zernike phase-contrast methods to circumvent this problem and measure these quasi-static aberrations at a nanometric level. We present the design, manufacturing, and testing of ZELDA, a prototype that was installed on VLT/SPHERE during its reintegration in Chile. Using the internal light source of the instrument, we first performed measurements in the presence of Zernike or Fourier modes introduced with the deformable mirror. Our experimental results are consistent with the results in simulations, confirming the ability of our sensor to measure small aberrations (<50 nm rms) with nanometric accuracy. Following these results, we corrected the long-lived non-common path aberrations in SPHERE based on ZELDA measurements and estimated a contrast gain of 10 in the coronagraphic image at 0.2'', reaching the raw contrast limit set by the coronagraph in the instrument. In addition to this encouraging result, the simplicity of the design and its phase reconstruction algorithm makes ZELDA an excellent candidate for the online measurements of quasi-static aberrations during the observations. The implementation of a ZELDA-based sensing path on the current and future facilities (ELTs, future space missions) could facilitate the observation of cold gaseous or massive rocky planets around nearby stars.
Context. The study of the inner region of the Milky Way bulge is hampered by high interstellar extinction and extreme source crowding. Sensitive high angular resolution near-infrared imaging is ...needed to study stellar populations and their characteristics in such a dense and complex environment. Aims. We aim at investigating the stellar population in the innermost Galactic bulge, to study the star formation history in this region of the Galaxy. Methods. We used the 0.2″ angular resolution JHKs data from the GALACTICNUCLEUS survey to study the stellar population within two 8.0′×3.4′ fields, about 0.6° and 0.4° to the Galactic north of the Milky Way centre and to compare it with the one in the immediate surroundings of Sagittarius A*. We also characterise the absolute extinction and the extinction curve of the two fields. Results. The average interstellar extinction to the outer and the inner field is AKs ∼ 1.20 ± 0.08 mag and ∼1.48 ± 0.10 mag, respectively. We present Ks luminosity functions that are complete down to at least two magnitudes below the red clump (RC). We detect a feature in the luminosity functions that is fainter than the RC by 0.80 ± 0.03 and 0.79 ± 0.02 mag, respectively, in the Ks band. It runs parallel to the reddening vector. We identify the feature as the red giant branch bump. Fitting α-enhanced BaSTI luminosity functions to our data, we find that a single old stellar population of ∼12.8 ± 0.6 Gyr and Z = 0.040 ± 0.003 provides the best fit. Our findings thus show that the stellar population in the innermost bulge is old, similar to the one at larger distances from the Galactic plane, and that its metallicity is about twice solar at distances as short as about 60 pc from the centre of the Milky Way, similar to what is observed at about 500 pc from the Galactic Centre. Comparing the obtained metallicity with previous known values at larger latitudes (|b| > 2°), our results favour a flattening of the gradient at |b| < 2°. As a secondary result we obtain that the extinction index in the studied regions agrees within the uncertainties with our previous value of α = 2.30 ± 0.08 that was derived for the very Galactic centre.
To determine using swept-source optical coherence tomography (SS-OCT) whether there are differences in the location of the anterior lamina cribrosa insertion (ALI) in primary open-angle glaucoma ...(POAG) patients and healthy subjects.
Fifty three eyes from 53 patients with POAG, and 53 eyes from 53 age-matched healthy subjects were included prospectively in Seoul National University Bundang Hospital. Twelve radial line B-scans centered on the optic disc in every half-clock-hour meridian were acquired using SS-OCT. The ALI position was assessed by measuring two parameters: (1) ALI distance (ALID)--the distance from the anterior scleral canal opening (ASCO) to the ALI; and (2) marginal anterior lamina cribrosa surface depth (mALCSD)--the perpendicular distance from the ASCO plane to the anterior lamina cribrosa surface. These parameters were compared between the two groups for each meridian.
Both ALID (256 ± 54 vs. 209 ± 37 µm, mean ± SD, p < 0.001) and mALCSD (232 ± 63 vs. 187 ± 40 µm, p < 0.001) were significantly greater in the POAG group than in the normal group. The largest difference was observed at the 6.5 o'clock and 11.5 o'clock meridians for both ALID and mALCSD. Multiple regression analysis revealed a negative correlation between age and both ALID and mALCSD in the control group, and a negative correlation between mean deviation of the visual field test and both ALID and mALCSD in the POAG group.
The ALI was displaced posteriorly in eyes with POAG compared to those of healthy controls. This finding suggests that the posteriorly located lamina cribrosa insertion is an important component of glaucomatous optic nerve excavation.
The long-term management of tailings from former uranium (U) mines requires an in-depth understanding of the hydrogeological processes and water flow paths. In France, most of the legacy U mines are ...located in fractured crystalline (plutonic) rocks, where the intrinsic subsurface heterogeneity adds to the uncertainties about the former extraction and milling activities and the state of the mine when production was ceased. U ores were mainly processed by sulfuric acid leaching, leading to high-sulfate-content mill tailings now contained in several tailing storage facilities (TSFs). The La Ribière site, located in western central France, is a former open-pit and underground U mine, closed in 1992 and used to store mill tailings. This site is being used as a test case to establish a workflow in order to explain and predict water flow and subsurface contaminant transport. A conceptual model of water flow and sulfate transport, at the scale of the La Ribière watershed, is first developed based on available information and hydrogeochemical monitoring. Recent geophysical investigations allows refining this model. Electrical Resistivity Tomography (ERT) proves to be efficient at localizing the extent of the highly conductive sulfate plume inherited from the U-mill tailings, but also at imaging the weathering profile. Magnetic Resonance Sounding (MRS), despite the limited signal intensity due to the low porosity in crystalline rocks, gives some insight into the porosity values, the depth of the fractured layer and the location of the low-porosity ore-processing muds. Based on this conceptual model, a 3D flow and non-reactive transport model with the METIS code is developed and calibrated. This model allows predicting the evolution of the sulfate plume, but will also be used in future investigations, to build reactive transport models with simplified hydrogeology for U and other reactive contaminants.
•Parsimonious approach to modeling a small but complex site with large uncertainties.•Water table and long-term sulfate monitoring highly valuable for model calibration.•Sulfate plume extent localized thanks to ERT sounding.•Boundaries of underground workings in former open pit identified by MRS sounding.
To investigate the variation of lamina cribrosa (LC) structure based on the baseline intraocular pressure (IOP) in eyes with primary open-angle glaucoma (POAG) and healthy individuals using ...swept-source optical coherence tomography.
A total of 108 eyes with POAG and 61 healthy eyes were recruited. Based on the baseline IOP, the POAG eyes were divided into higher-baseline IOP (HTG; baseline IOP > 21 mmHg, n = 38 eyes) and lower-baseline IOP (NTG; baseline IOP ≤ 21 mmHg, n = 70 eyes). The anterior laminar insertion depth (ALID), mean LC depth (mLCD), and the LC curvature index (mLCD-ALID) were measured, and compared among the three groups. The regional variation of LC structure was evaluated by vertical-horizontal ALID difference.
The mLCD and LC curvature index were greatest in HTG eyes (520.3 ± 123.0 and 80.9 ± 30.7 μm), followed by NTG (463.2 ± 110.5 and 64.5 ± 30.7 μm) and healthy eyes (382.9 ± 107.6 and 47.6 ± 25.7 μm, all P < 0.001). However, there were no significant difference in ALID between HTG and NTG eyes. The vertical-horizontal ALID difference was larger in NTG eyes (72.8 ± 56.2 μm) than in HTG (32.7 ± 61.4 μm, P = 0.004) and healthy eyes (25.5 ± 34.8 μm, P < 0.001).
Lamina cribrosa position and curvature differed in POAG eyes with low and high IOP. This would support the theory that IOP induced biomechanical effects on the optic play a role on glaucoma.
To investigate lamina cribrosa (LC) displacement during the Valsalva maneuver in young healthy eyes using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT).
...Forty-eight eyes of 48 young healthy volunteers (age range: 20-34 years) underwent intraocular pressure (IOP) measurement by Goldmann applanation tonometry as well as Cirrus HD-OCT scans before and during the Valsalva maneuver. The optic nerve head (ONH) parameters (average retinal nerve fiber layer thickness, rim area, disc area, average C/D ratio, vertical C/D ratio, cup volume), anterior LC depth (LCD), subfoveal and peripapillary choroidal thickness, and neural canal opening diameter were measured on compensated OCT and compared during Valsalva challenge. The subjects were asked to take a five-minute break after each Valsalva maneuver.
During the Valsalva maneuver, the IOP significantly increased, from 12.7 ± 3.0 mmHg to 16.0 ± 3.2 mmHg (P < 0.001), while the LCD sharply decreased, from 463.4 ± 118.8 μm to 427.3 ± 106.4 μm (P < 0.001). The subfoveal choroidal thickness (300.7 ± 90.6 vs. 309.6 ± 93.5 μm), peripapilllary choroidal thickness (152.2 ± 55.4 vs. 150.8 ± 49.3 μm), neural canal opening diameter (1651.8 ± 204.2 vs. 1651.0 ± 217.6 μm), and all of the ONH parameters did not change significantly (all P > 0.05).
The Valsalva maneuver induced anterior displacement of the LC, but did not alter the choroidal thickness or ONH morphology. The data describe the positional characteristics of the LC in response to the Valsalva maneuver in young healthy eyes.