Under certain running conditions, the CERN Large Hadron Collider (LHC) can be considered as a photon–photon collider. Indeed, in proton–proton, proton–ion, ion–ion collisions, when incoming particles ...pass very close to each other in very peripheral collisions, the incoming protons or ions remain almost intact and continue their path along the beam axis. Then, only the electromagnetic (EM) fields of these ultra-relativistic charged particles (protons or ions) interact to leave a signature in the central detectors of the LHC experiments. The interest is that the photon–photon interactions happen at unprecedented energies (a few TeV per nucleon pairs) where the quantum electrodynamics (QED) theory can be tested in extreme conditions and unforeseen laws of nature could be discovered. In this report, we propose a focus on a particular reaction, called light-by-light scattering in which two incoming photons interact, producing another pair of photons. We describe how experimental results have been obtained at the LHC. In addition, we discuss prospects for on-shell photon–photon interactions in dedicated laser beam facilities. Potential signatures of new physics might manifest as resonant deviations in the refractive index, induced by anomalous light-by-light scattering effects. Importantly, we explain how this process can be used to probe the physics beyond the standard model such as theories that include large extra dimensions. Finally, some perspectives and ideas are given for future data taking or experiments.
An overview of the latest ultra-peripheral physics measurements performed with the ATLAS detector at the LHC is presented. These include measurements of light-by-light scattering, which result in an ...observation of this elusive Standard Model process and set competitive limits on the parameter space for axion-like particles, differential measurements of the exclusive di-muon production cross-section, which are crucial for setting constraints on the initial photon spectrum for all ultra-peripheral collision measurements at the LHC and measurements of collective behavior in high-multiplicity photo-nuclear collisions.
Treacher Collins syndrome (TCS) is a rare congenital disorder of craniofacial development characterized by numerous developmental anomalies that are restricted to the head and neck. Most TCS cases ...are inherited in an autosomal dominant manner. The diagnosis of TCS relies on clinical and radiographic findings. The four genes involved in TCS are
,
and
.
In this report, we present the case of a 7-year-old Moroccan boy who exhibited distinctive dysmorphic features, including coloboma and zygomatic bone hypoplasia. Upon genetic analysis, a mutation in the
gene was identified, conclusively confirming the presence of Treacher Collins Syndrome. It is worthy that the correct etiological diagnosis was significantly delayed due to the initial misperception that the observed malformation syndrome was a result of drug teratogenicity.
This case highlights the importance of seeking pharmacovigilance advice if any adverse event occurs following medication use. Furthermore, requesting a genetic consultation to establish a confirmed etiological diagnosis for any malformation syndrome can significantly reduce the protracted social and psychological suffering that patients and their families may endure.
The association between the single nucleotide polymorphism rs762551 in the cytochrome P450 family 1, subfamily A2 gene (CYP1A2) and caffeine consumption remains controversial. We conducted a ...meta-analysis to clarify this potential association. Twelve studies were selected from articles retrieved from the and Google Scholar databases, and the data were analyzed to determine the odds ratio (OR) of genotypes AA (conferring fast caffeine metabolism) vs AC + CC (conferring slow caffeine metabolism). Comparisons were made between 6161 high caffeine consumers and 3219 low caffeine consumers. The overall analysis showed a significant association between genotype AA and coffee intake OR = 1.13, 95% confidence interval (CI) = 1.03-1.24; Q = 19.23, P = 0.06; I2 = 43%. In subgroup analyses, the association was also found within male, younger, and Caucasian subjects (OR = 1.21, 95%CI = 1.08- 1.35; OR = 1.71, 95%CI = 1.18-2.48; OR = 1.29, 95%CI = 1.12-1.49, respectively) but not in female, older, and Asian subjects (OR = 0.98, 95%CI = 0.83-1.15; OR = 0.83, 95%CI = 0.56-1.22; OR = 0.91, 95%CI = 0.71-1.17, respectively). Therefore, the rs762551 AA genotype may lead to higher coffee intake, especially in males, younger age groups, and individuals of Caucasian ethnicity. Our data highlight the need to test other CYP1A2 polymorphisms showing significance in genome-wide association studies to clarify the association with caffeine intake in the Asian population.
A search for the electroweak production of charginos and sleptons decaying into final states with two electrons or muons is presented. The analysis is based on 139 fb−1 of proton–proton collisions ...recorded by the ATLAS detector at the Large Hadron Collider at s√=13 TeV. Three R-parity-conserving scenarios where the lightest neutralino is the lightest supersymmetric particle are considered: the production of chargino pairs with decays via either W bosons or sleptons, and the direct production of slepton pairs. The analysis is optimised for the first of these scenarios, but the results are also interpreted in the others. No significant deviations from the Standard Model expectations are observed and limits at 95% confidence level are set on the masses of relevant supersymmetric particles in each of the scenarios. For a massless lightest neutralino, masses up to 420 GeV are excluded for the production of the lightest-chargino pairs assuming W-boson-mediated decays and up to 1 TeV for slepton-mediated decays, whereas for slepton-pair production masses up to 700 GeV are excluded assuming three generations of mass-degenerate sleptons.
This article documents the muon reconstruction and identification efficiency obtained by the ATLAS experiment for 139
fb
-
1
of
pp
collision data at
s
=
13
TeV collected between 2015 and 2018 during ...Run 2 of the LHC. The increased instantaneous luminosity delivered by the LHC over this period required a reoptimisation of the criteria for the identification of prompt muons. Improved and newly developed algorithms were deployed to preserve high muon identification efficiency with a low misidentification rate and good momentum resolution. The availability of large samples of
Z
→
μ
μ
and
J
/
ψ
→
μ
μ
decays, and the minimisation of systematic uncertainties, allows the efficiencies of criteria for muon identification, primary vertex association, and isolation to be measured with an accuracy at the per-mille level in the bulk of the phase space, and up to the percent level in complex kinematic configurations. Excellent performance is achieved over a range of transverse momenta from 3 GeV to several hundred GeV, and across the full muon detector acceptance of
|
η
|
<
2.7
.
A search for heavy neutral Higgs bosons is performed using the LHC Run 2 data, corresponding to an integrated luminosity of 139 fb−1 of proton-proton collisions at √s = 13 TeV recorded with the ...ATLAS detector. The search for heavy resonances is performed over the mass range 0.2–2.5 TeV for the τ+ τ− decay with at least one τ -lepton decaying into final states with hadrons. The data are in good agreement with the background prediction of the standard model. In the Mh125 scenario of the minimal supersymmetric standard model, values of tan β > 8 and tan β > 21 are excluded at the 95% confidence level for neutral Higgs boson masses of 1.0 and 1.5 TeV, respectively, where tan β is the ratio of the vacuum expectation values of the two Higgs doublets.
A search for the dimuon decay of the Standard Model (SM) Higgs boson is performed using data corresponding to an integrated luminosity of 139 fb−1 collected with the ATLAS detector in Run 2 pp ...collisions at s=13 TeV at the Large Hadron Collider. The observed (expected) significance over the background-only hypothesis for a Higgs boson with a mass of 125.09 GeV is 2.0σ (1.7σ). The observed upper limit on the cross section times branching ratio for pp→H→μμ is 2.2 times the SM prediction at 95% confidence level, while the expected limit on a H→μμ signal assuming the absence (presence) of a SM signal is 1.1 (2.0). The best-fit value of the signal strength parameter, defined as the ratio of the observed signal yield to the one expected in the SM, is μ=1.2±0.6.
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