In the last few years, transgender and gender nonconforming people have become more visible in our society, which has sparked a marked increase in awareness, interest, and attention among ...psychologists. Questions have emerged about the extent to which psychologists are able to work competently with this population. This article presents a framework for understanding key clinical issues that psychologists who work with transgender and gender nonconforming individuals will likely encounter in their clinical work. This article does not address the knowledge and skills required to provide services related to gender transition, but rather to provide other psychological services that these clients may need, in light of the high levels of gender-related victimization and discrimination to which they are exposed. An adaptation of the Minority Stress Model (Meyer, 2003) is presented and translated to incorporate the unique experiences encountered by transgender and gender nonconforming individuals. In particular, we examine adverse experiences that are closely related to gender identity and expression, resulting expectations for future victimization or rejection, and internalized transphobia. The impact of Minority Stress Model factors on suicide attempts is presented as a detailed example. Mechanisms by which transgender and gender nonconforming persons develop resilience to the negative psychological effects of these adverse experiences are also discussed. Recommendations for clinicians are then made to assist psychologists in developing competence in working with this population.
Effects of violence on transgender people Testa, Rylan J; Sciacca, Laura M; Wang, Florence ...
Professional psychology, research and practice,
10/2012, Letnik:
43, Številka:
5
Journal Article
Recenzirano
While recent research on transgender populations has demonstrated high rates of experiencing violence, there has been little research attention to the mental health implications of these experiences. ...This study utilized data collected from the Virginia Transgender Health Initiative Survey (THIS) of transgender people (individuals who described their gender identity as different from their sex assigned at birth) collected from 2005–2006. Current study analyses were limited to two subgroups: trans women (n = 179) and trans men (n = 92). We hypothesized that, as in the general population, exposure to physical and sexual violence would be related to suicidal ideation, suicide attempts, and substance abuse. Both trans women and trans men in this sample were at high risk for physical and sexual violence, as well as suicidal ideation and suicide attempt. Logistic regression analyses indicated that among both trans women and trans men, those who had endured physical and/or sexual violence were significantly more likely than those who had not had such experiences to report a history of suicide attempt and multiple suicide attempts. In addition, among trans men, history of physical and sexual violence were each related to alcohol abuse. Among trans women, history of sexual violence was related to alcohol abuse and illicit substance use. Patterns of violence against transgender people were identified and are discussed, including frequent gender-related motivation for violence, low prevalence of reporting violence to police, and variety of perpetrators of violence. Clinical implications and recommendations are provided. (PsycINFO Database Record (c) 2016 APA, all rights reserved) (Source: journal abstract)
This article presents empirical research findings from a subsample of 290 transgender participants in the Virginia Transgender Health Initiative Survey (THIS) who reported whether or not they had ...experienced hostility or insensitivity related to their gender identity or expression during high school, termed in-school gender-based victimization (GBV). The purpose of this study was to assess the impact of in-school GBV on rates of suicide attempts among transgender people. Of the 290 respondents, 44.8% reported they had experienced in-school GBV, and 28.5% reported a history of suicide attempt. Among those who had attempted, 32.5% reported having made one attempt, 28.6% reported a history of two attempts, and 39.0% reported having made three or more attempts. Participants who reported experiencing GBV were approximately four times more likely to have attempted suicide than those who did not. Among the subgroups of 147 trans women and 81 trans men, GBV was associated both with history of suicide attempt, and with a higher number of suicide attempts over the life span. Implications for policy and clinical interventions are discussed.
Ecosystem respiration Solomon, Christopher T.; Bruesewitz, Denise A.; Richardson, David C. ...
Limnology and oceanography,
20/May , Letnik:
58, Številka:
3
Journal Article
Recenzirano
Odprti dostop
We assembled data from a global network of automated lake observatories to test hypotheses regarding the drivers of ecosystem metabolism. We estimated daily rates of respiration and gross primary ...production (GPP) for up to a full year in each lake, via maximum likelihood fits of a free-water metabolism model to continuous high-frequency measurements of dissolved oxygen concentrations. Uncertainties were determined by a bootstrap analysis, allowing lake-days with poorly constrained rate estimates to be down-weighted in subsequent analyses. GPP and respiration varied considerably among lakes and at seasonal and daily timescales. Mean annual GPP and respiration ranged from 0.1 to 5.0 mg O2 L−1 d−1 and were positively related to total phosphorus but not dissolved organic carbon concentration. Within lakes, significant day-to-day differences in respiration were common despite large uncertainties in estimated rates on some lake-days. Daily variation in GPP explained 5% to 85% of the daily variation in respiration after temperature correction. Respiration was tightly coupled to GPP at a daily scale in oligotrophic and dystrophic lakes, and more weakly coupled in mesotrophic and eutrophic lakes. Background respiration ranged from 0.017 to 2.1 mg O₂ L−1 d−1 and was positively related to indicators of recalcitrant allochthonous and autochthonous organic matter loads, but was not clearly related to an indicator of the quality of allochthonous organic matter inputs.
Recurrent HSV-1 ocular disease results from reactivation of latent virus in trigeminal ganglia, often following immunosuppression or exposure to a variety of psychological or physical stressors. ...HSV-specific CD8+ T cells can block HSV-1 reactivation from latency in ex vivo trigeminal ganglia cultures through production of IFN-gamma. In this study, we establish that either CD8+ T cell depletion or exposure to restraint stress permit HSV-1 to transiently escape from latency in vivo. Restraint stress caused a reduction of TG-resident HSV-specific CD8+ T cells and a functional compromise of those cells that survive. Together, these effects of stress resulted in an approximate 65% reduction of cells capable of producing IFN-gamma in response to reactivating virus. Our findings demonstrate persistent in vivo regulation of latent HSV-1 by CD8+ T cells, and strongly support the concept that stress induces HSV-1 reactivation from latency at least in part by compromising CD8+ T cell surveillance of latently infected neurons.
HSV-specific CD8(+) T cells provide constant immunosurveillance of HSV-1 latently infected neurons in sensory ganglia, and their functional properties are influenced by the presence of latent virus. ...In this study, we show that ganglionic HSV-specific CD8(+) T cells exhibit a higher functional avidity (ability to respond to low epitope density) than their counterparts in noninfected lungs, satisfying a need for memory effector cells that can respond to low densities of viral epitopes on latently infected neurons. We further show that lack of CD4(+) T cell help during priming leads to a transient inability to control latent virus, which was associated with a PD-1/PD-L1 mediated reduced functional avidity of ganglionic HSV-specific CD8(+) T cells. CD4(+) T cells are not needed to maintain CD8(+) T cell memory through 34 d after infection, nor do they have a direct involvement in the maintenance of HSV-1 latency.
Abstract Objective The aim of this study is to examine whether school food attenuates household income-related disparities in adolescents' frequency of fruit and vegetable intake (FVI). Method ...Telephone surveys were conducted between 2007 and 2008 with adolescent-parent dyads from Northern New England; participants were randomly assigned to be surveyed at different times throughout the year. The main analysis comprised 1542 adolescents who typically obtained breakfast/lunch at school at least once/week. FVI was measured using 7-day recall of the number of times adolescents consumed fruits and vegetables. Fully adjusted linear regression was used to compare FVI among adolescents who were surveyed while school was in session (currently exposed to school food) to those who were surveyed when school was not in session (currently unexposed to school food). Results Mean FVI was 8.0 (SD = 5.9) times/week. Among adolescents unexposed to school food, household income and FVI were strongly, positively associated. In contrast, among adolescents exposed to school food, FVI was similar across all income categories. We found a significant cross-over interaction between school food and household income in which consuming food at school was associated with higher FVI among adolescents from low-income households versus lower FVI among adolescents from high-income households. Conclusion School food may mitigate income disparities in adolescent FVI. The findings suggest that the school food environment positively influences FVI among low-income adolescents.
Psychological research with transgender and gender nonconforming (TGNC) people is a relatively new field with great promise to advance our understanding of this population's needs and develop, ...implement, and evaluate corresponding interventions to reduce their health disparities and promote psychosocial adjustment, mental health, and well-being. After a brief review of the history of research with TGNC people, this article discusses several issues to ensure that research with this population is culturally competent and meaningful. This includes issues to consider for participant recruitment, data collection, working with institutional review boards, and distribution of research findings. We conclude with a discussion of gaps in the literature and corresponding opportunities for future psychological research with TGNC people.
Monte Carlo-linked depletion methods have gained recent interest due to the ability to model complex three-dimensional geometries using continuous-energy cross sections. The integration of CINDER90 ...into the MCNPX Monte Carlo radiation transport code provides a completely self-contained Monte Carlo-linked depletion capability in a single Monte Carlo code that is compatible with most nuclear criticality (KCODE) particle tracking features in MCNPX. MCNPX depletion tracks all necessary reaction rates and follows as many isotopes as cross-section data permit. The objective of this work is (a) describe the MCNPX depletion methodology dating from the original linking of MONTEBURNS and MCNP to the first public release of the integrated capability (MCNPX 2.6.B, June 2006) that has been reported previously, (b) further detail the many new depletion capability enhancements since then leading to the present Radiation Safety Information Computational Center (RSICC) release, MCNPX 2.6.0, (c) report calculation results for the H. B. Robinson benchmark, and (d) detail new features available in MCNPX 2.7.A.
Each version of MCNPX depletion starting from MCNPX 2.6.A leading to the official RSICC release of MCNPX 2.6.0 and the new beta release MCNPX 2.7.A included significant upgrades that addressed key issues from earlier versions. This paper details these key issues and the approach utilized to address the issues as enhancements for MCNPX 2.6.0. The MCNPX 2.6.0 depletion capability enhancements include (a) allowing the modeling of as large a system as computer memory capacity permits; (b) tracking every fission product available in ENDF/B VII.0; (c) enabling depletion in repeated structures geometries such as repeated arrays of fuel pins; (d) including metastable isotopes in burnup; and (e) manually changing the concentrations of any isotope during any time step by specified atom fraction, weight fraction, atom density, or gram density. These enhancements allow better detail to model the true system physics as well as to improve the robustness of the capability.
H. B. Robinson benchmark calculations were completed to assess the validity of nuclide predictability of MCNPX 2.6.0. The results show comparisons of key actinide and fission products as compared to experiment and the SCALE-4 SAS2H sequence 27-group cross-section library (27BURNUPLIB) results. MCNPX 2.6.0 depletion results are within 4% of the experimental results for most major actinides.
Two major depletion enhancements are available in the MCNPX 2.7.A beta release: improved 63-group flux querying and parallelization of the burnup interface routines in multiprocessor mode. Fixing the energy group querying routine does correctly tally the energy flux for use with isotopes not containing transport cross sections; however, results show <1% change in nuclide prediction for the benchmark test case. MCNPX 2.7.A parallelizes the depletion interface routines and running of CINDER90 so that different burnable regions of a given depletion system can be preprocessed, burned, and postprocessed on separate slave processors. The parallelization involves minimal communication between processors and therefore leads to significant computational performance enhancement.
The combination of new enhancements and testing of the MCNPX 2.6.0 depletion computational system make this capability a valuable Monte Carlo-linked depletion tool. Additional testing and feature enhancements are under development to further improve the usefulness of the computational tool.
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