The coronavirus disease 2019 (COVID-19) epidemic affects people's health and health-related quality of life (HRQoL), especially in those who have suspected COVID-19 symptoms (S-COVID-19-S). We ...examined the effect of modifications of health literacy (HL) on depression and HRQoL. A cross-sectional study was conducted from 14 February to 2 March 2020. 3947 participants were recruited from outpatient departments of nine hospitals and health centers across Vietnam. The interviews were conducted using printed questionnaires including participants' characteristics, clinical parameters, health behaviors, HL, depression, and HRQoL. People with S-COVID-19-S had a higher depression likelihood (OR, 2.88;
< 0.001), lower HRQoL-score (B, -7.92;
< 0.001). In comparison to people without S-COVID-19-S and low HL, those with S-COVID-19-S and low HL had 9.70 times higher depression likelihood (
< 0.001), 20.62 lower HRQoL-score (
< 0.001), for the people without S-COVID-19-S, 1 score increment of HL resulted in 5% lower depression likelihood (
< 0.001) and 0.45 higher HRQoL-score (
< 0.001), while for those people with S-COVID-19-S, 1 score increment of HL resulted in a 4% lower depression likelihood (
= 0.004) and 0.43 higher HRQoL-score (
< 0.001). People with S-COVID-19-S had a higher depression likelihood and lower HRQoL than those without. HL shows a protective effect on depression and HRQoL during the epidemic.
The most precise top quark mass measurements use kinematic reconstruction methods, determining the top mass parameter of a Monte Carlo event generator m_{t}^{MC}. Because of hadronization and ...parton-shower dynamics, relating m_{t}^{MC} to a field theory mass is difficult. We present a calibration procedure to determine this relation using hadron level QCD predictions for observables with kinematic mass sensitivity. Fitting e^{+}e^{-} 2-jettiness calculations at next-to-leading-logarithmic and next-to-next-to-leading-logarithmic order to pythia 8.205, m_{t}^{MC} differs from the pole mass by 900 and 600 MeV, respectively, and agrees with the MSR mass within uncertainties, m_{t}^{MC}≃m_{t,1 GeV}^{MSR}.
Electrodeposition of CuAg alloy films from plating baths containing 3,5-diamino-1,2,4-triazole (DAT) as an inhibitor yields high surface area catalysts for the active and selective electroreduction ...of CO2 to multicarbon hydrocarbons and oxygenates. EXAFS shows the co-deposited alloy film to be homogeneously mixed. The alloy film containing 6% Ag exhibits the best CO2 electroreduction performance, with the Faradaic efficiency for C2H4 and C2H5OH production reaching nearly 60 and 25%, respectively, at a cathode potential of just −0.7 V vs RHE and a total current density of ∼ – 300 mA/cm2. Such high levels of selectivity at high activity and low applied potential are the highest reported to date. In situ Raman and electroanalysis studies suggest the origin of the high selectivity toward C2 products to be a combined effect of the enhanced stabilization of the Cu2O overlayer and the optimal availability of the CO intermediate due to the Ag incorporated in the alloy.
We aimed to evaluate the microbiological characteristics and risk factors for mortality of infective endocarditis in two tertiary hospitals in Ho Chi Minh City, south Vietnam.
A retrospective study ...of 189 patients (120 men, 69 women; mean age 38 ± 18 years) with the diagnosis of probable or definite infective endocarditis (IE) according to the modified Duke Criteria admitted to The Heart Institute or Tam Duc Hospital between January 2005 and December 2014.
IE was related to a native valve in 165 patients (87.3%), and prosthetic valve in 24 (12.7%). Of the 189 patients in our series, the culture positive rate was 70.4%. The most common isolated pathogens were Streptococci (75.2%), Staphylococci (9.8%) followed by gram negative organism (4.5%). The sensitivity rate of Streptococci to ampicillin, ceftriaxone or vancomycin was 100%. The rate of methicillin resistant Staphylococcus aureus was 40%. There was a decrease in penicillin sensitivity for Streptococci over three eras: 2005-2007 (100%), 2008-2010 (94%) and 2010-2014 (84%). The in-hospital mortality rate was 6.9%. Logistic regression analysis found prosthetic valve and NYHA grade 3 or 4 heart failure and vegetation size of more than 15 mm as strong predictors of in-hospital mortality.
Streptococcal species were the major pathogen of IE in the recent years with low rates of antimicrobial resistance. Prosthetic valve involvement, moderate or severe heart failure and vegetation size of more than 15 mm were independent predictors for in-hospital mortality in IE.
To investigate factors associated with survival after out-of-hospital cardiac arrest in Viet Nam.
We did a multicentre prospective observational study of people (> 18 years) presenting with ...out-of-hospital cardiac arrest (not caused by trauma) to three tertiary hospitals in Viet Nam from February 2014 to December 2018. We collected data on characteristics, management and outcomes of patients with out-of-hospital cardiac arrest and compared these data by type of transportation to hospital and survival to hospital admission. We assessed factors associated with survival to admission to and discharge from hospital using logistic regression analysis.
Of 590 eligible people with out-of-hospital cardiac arrest, 440 (74.6%) were male and the mean age was 56.1 years (standard deviation: 17.2). Only 24.2% (143/590) of these people survived to hospital admission and 14.1% (83/590) survived to hospital discharge. Most cardiac arrests (67.8%; 400/590) occurred at home, 79.4% (444/559) were witnessed by bystanders and 22.3% (124/555) were given cardiopulmonary resuscitation by a bystander. Only 8.6% (51/590) of the people were taken to hospital by the emergency medical services and 32.2% (49/152) received pre-hospital defibrillation. Pre-hospital defibrillation (odds ratio, OR: 3.90; 95% confidence interval, CI: 1.54-9.90) and return of spontaneous circulation in the emergency department (OR: 2.89; 95% CI: 1.03-8.12) were associated with survival to hospital admission. Hypothermia therapy during post-resuscitation care was associated with survival to discharge (OR: 5.44; 95% CI: 2.33-12.74).
Improvements are needed in the emergency medical services in Viet Nam such as increasing bystander cardiopulmonary resuscitation and public access defibrillation, and improving ambulance and post-resuscitation care.
Bronchopulmonary dysplasia (BPD) is a severe condition in premature infants that compromises lung function and necessitates oxygen support. Despite major improvements in perinatal care minimizing the ...devastating effects, BPD remains the most frequent complication of extreme preterm birth. Our study reports the safety of the allogeneic administration of umbilical cord-derived mesenchymal stem/stromal cells (allo-UC-MSCs) and the progression of lung development in four infants with established BPD.
UC tissue was collected from a healthy donor, followed by propagation at the Stem Cell Core Facility at Vinmec Research Institute of Stem Cell and Gene Technology. UC-MSC culture was conducted under xeno- and serum-free conditions. Four patients with established BPD were enrolled in this study between May 25, 2018, and December 31, 2018. All four patients received two intravenous doses of allo-UC-MSCs (1 million cells/kg patient body weight (PBW) per dose) with an intervening interval of 7 days. Safety and patient conditions were evaluated during hospitalization and at 7 days and 1, 6 and 12 months postdischarge.
No intervention-associated severe adverse events or prespecified adverse events were observed in the four patients throughout the study period. At the time of this report, all patients had recovered from BPD and were weaned off of oxygen support. Chest X-rays and CT scans confirmed the progressive reductions in fibrosis.
Allo-UC-MSC administration is safe in preterm infants with established BPD. Trial registration This preliminary study was approved by the Vinmec International Hospital Ethics Board (approval number: 88/2019/QĐ-VMEC; retrospectively registered March 12, 2019).
Striped catfish (Pangasianodon hypophthalmus) farming in the Mekong Delta Vietnam (MKDVN) importantly contributes to national aquaculture export. Currently, however, diseases occur more frequently ...across the entire MKDVN region. One of the most common types is hemorrhagic septicemia caused by Aeromonas hydrophila. In this study, isolation and selection of the phages for control in vitro Aeromonas hydrophila were conducted. 24 phages were isolated from 100 striped catfish pond water samples. Next, lytic activity of these phages was clarified. Four phages with short latent period (about 25 to 40 min) and/or high burst size (about 67 to 94 PFU/ cell) were selected to evaluate their infection activity to different phage-resistant A. hydrophila strains. Two phages termed as TG25P and CT45P were subjected to the phage cocktail to inactivate A. hydrophila. Re-growth of the host bacteria appeared about eight hours after treatment. Usage of the phage cocktail that attach different host bacterial receptors is not always much effective than usage of single phage. This is the first report about phage therapy to control A. hydrophila isolated from striped catfish. Some challenges in the phage cocktail were shown to achieve strategies in prospective studies in the context of high antibiotic resistance of A. hydrophila.
A
bstract
We provide a systematic renormalization group formalism for the mass effects in the relation of the pole mass
m
Q
pole
and short-distance masses such as the
M
S
¯
mass
m
¯
Q
of a heavy ...quark
Q
, coming from virtual loop insertions of massive quarks lighter than
Q
. The formalism reflects the constraints from heavy quark symmetry and entails a combined matching and evolution procedure that allows to disentangle and successively integrate out the corrections coming from the lighter massive quarks and the momentum regions between them and to precisely control the large order asymptotic behavior. With the formalism we systematically sum logarithms of ratios of the lighter quark masses and
m
Q
, relate the QCD corrections for different external heavy quarks to each other, predict the
O
α
s
4
virtual quark mass corrections in the pole-
M
S
¯
mass relation, calculate the pole mass differences for the top, bottom and charm quarks with a precision of around 20 MeV and analyze the decoupling of the lighter massive quark flavors at large orders. The summation of logarithms is most relevant for the top quark pole mass
m
t
pole
, where the hierarchy to the bottom and charm quarks is large. We determine the ambiguity of the pole mass for top, bottom and charm quarks in different scenarios with massive or massless bottom and charm quarks in a way consistent with heavy quark symmetry, and we find that it is 250 MeV. The ambiguity is larger than current projections for the precision of top quark mass measurements in the high-luminosity phase of the LHC.
Despite the progress that has been made in understanding radio relics, there are still open questions regarding the underlying particle acceleration mechanisms. In this paper, we present deep 1-4 GHz ...Very Large Array (VLA) observations of CIZA J2242.8+5301 (z = 0.1921), a double radio relic cluster characterized by small projection on the plane of the sky. Our VLA observations reveal, for the first time, the complex morphology of the diffuse sources and the filamentary structure of the northern relic. We discover new, faint, diffuse radio emission extending north of the main northern relic. Our Mach number estimates for the northern and southern relics, based on the radio spectral index map obtained using the VLA observations and existing LOw Frequency ARray (LOFAR) and Giant Metrewave Radio Telescope data, are consistent with previous radio and X-ray studies ( and ). However, color-color diagrams and models suggest a flatter injection spectral index than the one obtained from the spectral index map, indicating that projection effects might be not entirely negligible. The southern relic consists of five "arms." Embedded in it, we find a tailed radio galaxy that seems to be connected to the relic. A spectral index flattening, where the radio tail connects to the relic, is also measured. We propose that the southern relic may trace AGN fossil electrons that are reaccelerated by a shock, with an estimated strength of . High-resolution mapping of other tailed radio galaxies also supports a scenario where AGN fossil electrons are revived by the merger event and could be related to the formation of some diffuse cluster radio emission.
Several studies have shown a significant level of temperature and humidity heterogeneity, with non-uniform airflow in the refrigeration equipment, which lead to a deterioration in food quality and ...safety. As the product is present in several different types of equipment along the supply chain, it is difficult to control and maintain the temperature throughout the cold chain. Basic to advanced approaches, from field studies to combined deterministic and stochastic modelling, are presented in this review article. Deterministic modelling (heat/mass transfer, airflow, quality and microbiology) in cold chain equipment, and combined deterministic and stochastic modelling in food processing and the cold chain are presented. This approach makes it possible to take into account the variability of the input parameters of the model such as the initial product characteristic (moisture content, temperature, contamination, etc.) and the operating conditions (ambient temperature, residence time in the equipment etc.). This review provides an insight into the background, problematic and transfer mechanism of food refrigeration.