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Trenutno NISTE avtorizirani za dostop do e-virov UM. Za polni dostop se PRIJAVITE.

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zadetkov: 129
31.
  • Molecular Biology of Pediat... Molecular Biology of Pediatric Brain Tumors and Impact on Novel Therapies
    Hoffman, Lindsey M.; Salloum, Ralph; Fouladi, Maryam Current neurology and neuroscience reports, 04/2015, Letnik: 15, Številka: 4
    Journal Article
    Recenzirano

    Brain tumors are the leading cause of cancer-related death in children. For the past several decades, therapeutic strategies have centered on cytotoxic chemotherapy and radiation therapy due, in ...
Celotno besedilo
32.
  • Phase I trial of weekly MK-... Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study
    Hoffman, Lindsey M.; Fouladi, Maryam; Olson, James ... Child's nervous system, 08/2015, Letnik: 31, Številka: 8
    Journal Article
    Recenzirano
    Odprti dostop

    Purpose Amplification and high levels of NOTCH ligand expression have been identified in several types of pediatric brain tumors. A phase I trial of weekly MK-0752, an oral inhibitor of ...
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33.
  • The international diffuse i... The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease
    Baugh, Joshua; Bartels, Ute; Leach, James ... Journal of neuro-oncology, 04/2017, Letnik: 132, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    Diffuse intrinsic pontine glioma (DIPG), a rare, often fatal childhood brain tumor, remains a major therapeutic challenge. In 2012, investigators, funded by the DIPG Collaborative (a philanthropic ...
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34.
  • External validation of the ... External validation of the diffuse intrinsic pontine glioma survival prediction model: a collaborative report from the International DIPG Registry and the SIOPE DIPG Registry
    Veldhuijzen van Zanten, Sophie E. M.; Lane, Adam; Heymans, Martijn W. ... Journal of neuro-oncology, 08/2017, Letnik: 134, Številka: 1
    Journal Article
    Recenzirano
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    We aimed to perform external validation of the recently developed survival prediction model for diffuse intrinsic pontine glioma (DIPG), and discuss its utility. The DIPG survival prediction model ...
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35.
  • Multi‐institutional analysi... Multi‐institutional analysis of treatment modalities in basal ganglia and thalamic germinoma
    Graham, Richard T.; Abu‐Arja, Mohammad H.; Stanek, Joseph R. ... Pediatric blood & cancer, October 2021, Letnik: 68, Številka: 10
    Journal Article
    Recenzirano
    Odprti dostop

    Background Central nervous system (CNS) germinomas are treatment‐sensitive tumors with excellent survival outcomes. Current treatment strategies combine chemotherapy with radiotherapy (RT) in order ...
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36.
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37.
  • NF-κB upregulation through ... NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma
    Griesinger, Andrea M; Witt, Davis A; Grob, Sydney T ... Neuro-oncology, 10/2017, Letnik: 19, Številka: 10
    Journal Article
    Recenzirano
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    Inflammation has been identified as a hallmark of high-risk Group A (GpA) ependymoma (EPN). Chronic interleukin (IL)-6 secretion from GpA tumors drives an immune suppressive phenotype by polarizing ...
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38.
  • Development of the CNS TAP ... Development of the CNS TAP tool for the selection of precision medicine therapies in neuro-oncology
    Linzey, Joseph R.; Marini, Bernard L.; Pasternak, Amy ... Journal of neuro-oncology, 03/2018, Letnik: 137, Številka: 1
    Journal Article
    Recenzirano
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    The number of targeted therapies utilized in precision medicine are rapidly increasing. Neuro-oncology offers a unique challenge due to the varying blood brain barrier (BBB) penetration of each ...
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39.
  • Regulation of Myocilin-Asso... Regulation of Myocilin-Associated Exosome Release from Human Trabecular Meshwork Cells
    Hoffman, Emely A; Perkumas, Kristin M; Highstrom, Lindsey M ... Investigative ophthalmology & visual science, 03/2009, Letnik: 50, Številka: 3
    Journal Article
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    The goal of the present study was to determine whether the release of exosomes containing MYOC from trabecular meshwork (TM) cells is constitutive or regulated. Conditioned media from TM cells were ...
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40.
  • A modified IRS-III chemothe... A modified IRS-III chemotherapy regimen leads to prolonged survival in children with embryonal tumor with multilayer rosettes
    Hanson, Derek; Hoffman, Lindsey M; Nagabushan, Sumanth ... Neuro-oncology advances, 01/2020, Letnik: 2, Številka: 1
    Journal Article
    Recenzirano
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    Abstract Background Embryonal tumor with multilayer rosettes (ETMR) is a rare CNS malignancy affecting young children that carries a very poor prognosis. Treatment with intensive surgical resection, ...
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zadetkov: 129

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