The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically ...similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.
When bullets don't kill Barber, C W; Ozonoff, V V; Schuster, M ...
Public health reports (1974),
11/1996, Letnik:
111, Številka:
6
Journal Article
Recenzirano
The Massachusetts Department of Public Health has created the first statewide surveillance system in the nation that tracks both fatal and nonfatal weapon injuries. The authors summarize findings for ...1994 and discuss their public health implication. Suicides were the leading cause of firearm fatality, while self-inflicted injuries accounted for only 3% of nonfatal firearm injuries. Risk of violence-related injuries varied dramatically across the state. In Boston, one in 38 black male teenagers ages 15 to 19 was shot or stabbed in 1994, in contrast to one in 56,000 for white females of any age living in suburban communities. In Boston, non-Hispanic black male teenagers were at 41 times higher risk than white male teenagers for gun injuries. Shooting homicides increased sixfold during the late 1980s among black Boston males, while homicides by other means remained stable. In other Massachusetts cities, injury rates were higher among 20 to 24-year-olds than among teenagers, and, in some areas, incidence rates were as high or higher among Hispanic males than among non-Hispanic black males. Between 1985 and 1994, the proportion of firearm injuries caused by semiautomatic pistols increased from 23% to 52%, according to police ballistics data.
THE MASSACHUSETTS DEPARTMENT OF PUBLIC HEALTH has created the first statewide surveillance system in the nation that tracks both fatal and nonfatal weapon injuries. The authors summarize findings for ...1994 and discuss their public health implications. Suicides were the leading cause of firearm fatality, while self-inflicted injuries accounted for only 3% of nonfatal firearm injuries. Risk of violence-related injuries varied dramatically across the state. In Boston, one in 38 black male teenagers ages 15 to 19 was shot or stabbed in 1994, in contrast to one in 56,000 for white females of any age living in suburban communities. In Boston, non-Hispanic black male teenagers were at 41 times higher risk than white male teenagers for gun injuries. Shooting homicides increased sixfold during the late 1980s among black Boston males, while homicides by other means remained stable. In other Massachusetts cities, injury rates were higher among 20 to 24-year-olds than among teenagers, and, in some areas, incidence rates were as high or higher among Hispanic males than among non-Hispanic black males. Between 1985 and 1994, the proportion of firearm injuries caused by semiautomatic pistols increased from 23% to 52%, according to police ballistics data.
We present a new and innovative near-infrared multi-band ultraprecise spectroimager (NIMBUS) for SOFIA. This design is capable of characterizing a large sample of extrasolar planet atmospheres by ...measuring elemental and molecular abundances during primary transit and occultation. This wide-field spectroimager would also provide new insights into Trans-Neptunian Objects (TNO), Solar System occultations, brown dwarf atmospheres, carbon chemistry in globular clusters, chemical gradients in nearby galaxies, and galaxy photometric redshifts. NIMBUS would be the premier ultraprecise spectroimager by taking advantage of the SOFIA observatory and state of the art infrared technologies. This optical design splits the beam into eight separate spectral bandpasses, centered around key molecular bands from 1 to 4 microns. Each spectral channel has a wide field of view for simultaneous observations of a reference star that can decorrelate time-variable atmospheric and optical assembly effects, allowing the instrument to achieve ultraprecise calibration for imaging and photometry for a wide variety of astrophysical sources. NIMBUS produces the same data products as a low-resolution integral field spectrograph over a large spectral bandpass, but this design obviates many of the problems that preclude high-precision measurements with traditional slit and integral field spectrographs. This instrument concept is currently not funded for development.
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