On September 14, 2015 at 09:50:45 UTC the two detectors of the Laser Interferometer Gravitational-Wave Observatory simultaneously observed a transient gravitational-wave signal. The signal sweeps ...upwards in frequency from 35 to 250 Hz with a peak gravitational-wave strain of 1.0 x 10(exp -21). It matches the waveform predicted by general relativity for the inspiral and merger of a pair of black holes and the ring down of the resulting single black hole. The signal was observed with a matched-filter signal-to-noise ratio of 24 and a false alarm rate estimated to be less than 1 event per 203 000 years, equivalent to a significance greater than 5.1 Sigma. The source lies at a luminosity distance of 410(+160/-180) Mpc corresponding to a redshift z = 0.09(+0.03/-0.04). In the source frame, the initial black hole masses are 36(+5/-4) Mass compared to the sun, and 29(+4/-4) Mass compared to the sun, and the final black hole mass is 62(+4/-4) Mass compared to the sun, with 3.0(+0.5/-0.5)sq c radiated in gravitational waves. All uncertainties define 90% credible intervals. These observations demonstrate the existence of binary stellar-mass black hole systems. This is the first direct detection of gravitational waves and the first observation of a binary black hole merger.
Summary Background For all countries, information on pathogens causing healthcare-associated infections is important in order to develop proper strategies for preventing and treating nosocomial ...infections. Aim To assess the change in frequencies and antimicrobial resistance of pathogens causing device-associated infections (DAIs) in intensive care units (ICUs) in South Korea between July 2006 and June 2014. Methods Data from the Korean Nosocomial Infections Surveillance System (KONIS) were analysed, including three major DAI types in ICUs. Findings The frequency of Gram-negative bacteria gradually increased for central line-associated bloodstream infection (CLABSI) and ventilator-associated pneumonia (VAP) (from 24.6% to 32.6% and from 52.8% to 73.5%, respectively). By contrast, the frequency of Gram-positive bacteria decreased from 58.6% to 49.2% for CLABSI, and from 44.3% to 23.8% for VAP ( P < 0.001). Staphylococcus aureus was the most frequent causative pathogen in CLABSI throughout the surveillance period, but for VAP was replaced as the most frequent pathogen by Acinetobacter baumannii as of 2010. Candida albicans was the most frequent pathogen for catheter-associated urinary tract infection. The meticillin resistance rate in S. aureus decreased from 95% to 90.2% ( P < 0.001); amikacin resistance in Klebsiella pneumoniae and Escherichia coli decreased from 43.8% to 14.7% and from 15.0% to 1.8%, respectively ( P < 0.001); imipenem resistance in A. baumannii increased from 52.9% to 89.8% ( P < 0.001). Conclusion The proportion of Gram-negative bacteria as nosocomial pathogens for CLABSI and VAP has increased. The prevalence of A. baumannii causing DAIs in Korean ICUs has increased rapidly, as has the rate of carbapenem resistance in these bacteria.
Metal halide perovskites have been studied in semiconductor fields such as light-emitting diodes (LEDs) and solar cells owing to their simple manufacturing, high optoelectronic performance, and low ...manufacturing cost. In this regard, spin-coating method facilitates the fabrication of perovskite devices. However, the spin-coating method for perovskite film deposition is difficult to finely control the thickness and form a uniform surface. Thus. the thermal evaporation method was proposed to overcome these shortcomings. This method provides better reproducibility and film quality than the spin-coating method. In this review, the spin-coating method and thermal evaporation method used to manufacture perovskite thin films will be explained. Moreover, the basic principles of perovskite devices (LEDs, solar cells, memory, X-ray detectors) are explained, and research on perovskite devices developed using thermal evaporation is summarized.
This review summarizes the working principle of perovskite devices and studies on devices fabricated using the thermal evaporation method. The perovskite thermal evaporation method can use a single-source or a dual-source and synthesizes various perovskite structures through doping. This method provides better reproducibility and film quality compared to the conventional spin-coating method. Display omitted
Tests of General Relativity with GW150914 Aguiar, O D; Arceneaux, C C; Arnaud, N ...
Physical review letters,
2016-Jun-03, Letnik:
116, Številka:
22
Journal Article, Web Resource
Recenzirano
Odprti dostop
The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final ...merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity. Furthermore, the data following the peak of GW150914 are consistent with the least-damped quasinormal mode inferred from the mass and spin of the remnant black hole. By using waveform models that allow for parametrized general-relativity violations during the inspiral and merger phases, we perform quantitative tests on the gravitational-wave phase in the dynamical regime and we determine the first empirical bounds on several high-order post-Newtonian coefficients. We constrain the graviton Compton wavelength, assuming that gravitons are dispersed in vacuum in the same way as particles with mass, obtaining a 90%-confidence lower bound of 10^{13} km. In conclusion, within our statistical uncertainties, we find no evidence for violations of general relativity in the genuinely strong-field regime of gravity.
We report on the Balloon-borne Investigation of Temperature and Speed of Electrons in the corona (BITSE) mission launched recently to observe the solar corona from
≈
3
Rs to 15 Rs at four ...wavelengths (393.5, 405.0, 398.7, and 423.4 nm). The BITSE instrument is an externally occulted single stage coronagraph developed at NASA’s Goddard Space Flight Center in collaboration with the Korea Astronomy and Space Science Institute (KASI). BITSE used a polarization camera that provided polarization and total brightness images of size
1024
×
1024
pixels. The Wallops Arc Second Pointer (WASP) system developed at NASA’s Wallops Flight Facility (WFF) was used for Sun pointing. The coronagraph and WASP were mounted on a gondola provided by WFF and launched from the Fort Sumner, New Mexico station of Columbia Scientific Balloon Facility (CSBF) on September 18, 2019. BITSE obtained 17,060 coronal images at a float altitude of
≈
128,000
feet (
≈
39
km) over a period of
≈
4
hrs. BITSE flight software was based on NASA’s core Flight System, which was designed to help develop flight quality software. We used EVTM (Ethernet Via Telemetry) to download science data during operations; all images were stored on board using flash storage. At the end of the mission, all data were recovered and analyzed. Preliminary analysis shows that BITSE imaged the solar minimum corona with the equatorial streamers on the east and west limbs. The narrow streamers observed by BITSE are in good agreement with the geometric properties obtained by the Solar and Heliospheric Observatory (SOHO) coronagraphs in the overlapping physical domain. In spite of the small signal-to-noise ratio (
≈
14
) we were able to obtain the temperature and flow speed of the western steamer. In the heliocentric distance range 4 – 7 Rs on the western streamer, we obtained a temperature of
≈
1.0
±
0.3
MK and a flow speed of
≈
260
km s
−1
with a large uncertainty interval.
The use of an appropriate delivery system capable of protecting, translocating, and selectively releasing therapeutic moieties to desired sites can promote the efficacy of an active compound. In this ...work, we have developed a nanoformulation which preserves its magnetization to load a model anticancerous drug and to explore the controlled release of the drug in a cancerous environment. For the preparation of the nanoformulation, self-assembled magnetic nanospheres (MNS) made of superparamagnetic iron oxide nanoparticles were grafted with a monolayer of (3-aminopropyl)triethoxysilane (APTES). A direct functionalization strategy was used to avoid the loss of the MNS magnetization. The successful preparation of the nanoformulation was validated by structural, microstructural, and magnetic investigations. X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR) were used to establish the presence of APTES on the MNS surface. The amine content quantified by a ninhydrin assay revealed the monolayer coverage of APTES over MNS. The monolayer coverage of APTES reduced only negligibly the saturation magnetization from 77 emu/g (for MNS) to 74 emu/g (for MNS-APTES). Detailed investigations of the thermoremanent magnetization were carried out to assess the superparamagnetism in the MNS. To make the nanoformulation pH-responsive, the anticancerous drug Nintedanib (NTD) was conjugated with MNS-APTES through the acid liable imine bond. At pH 5.5, which mimics a cancerous environment, a controlled release of 85% in 48 h was observed. On the other hand, prolonged release of NTD was found at physiological conditions (i.e., pH 7.4). In vitro cytotoxicity study showed dose-dependent activity of MNS-APTES-NTD for human lung cancer cells L-132. About 75% reduction in cellular viability for a 100 μg/mL concentration of nanoformulation was observed. The nanoformulation designed using MNS and monolayer coverage of APTES has potential in cancer therapy as well as in other nanobiological applications.
Large Area Light Detectors With MMC Readouts Kim, M. B.; Chung, J. S.; Jeon, J. A. ...
IEEE transactions on applied superconductivity,
08/2023, Letnik:
33, Številka:
5
Journal Article
Recenzirano
We present the development of the light detectors with magnetic microcalorimeter (MMC) readouts designed for the AMoRE neutrinoless double beta decay experiment. The detectors are composed of Ge or ...Si wafer as an absorber for scintillation light and an MMC detector to monitor the temperature of the wafer. Five measurements were carried out with one Ge wafer and four Si wafers prepared under various conditions. Different details of the light detector assembly have been tested to find the optimal configuration for the future AMoRE-II experiment. Direct comparisons in signal size were performed with the different wafers while considering favorable conditions for the future AMoRE setup. Moreover, a baseline resolution of 34.3 eV FWHM was obtained in a detector setup with a 2-inch Si wafer.
On September 14, 2015 at 09:50:45 UTC the two detectors of the Laser Interferometer Gravitational-wave Observatory (LIGO) simultaneously observed the binary black hole merger GW150914. We report the ...results of a matched-filter search using relativistic models of compact-object binaries that recovered GW150914 as the most significant event during the coincident observations between the two LIGO detectors from September 12 to October 20, 2015. GW150914 was observed with a matched filter signal-to-noise ratio of 24 and a false alarm rate estimated to be less than 1 event per 203000 years, equivalent to a significance greater than 5.1
.
Following a major upgrade, the two advanced detectors of the Laser Interferometer Gravitational-wave Observatory (LIGO) held their first observation run between September 2015 and January 2016. With ...a strain sensitivity of 10^{-23}/sqrtHz at 100 Hz, the product of observable volume and measurement time exceeded that of all previous runs within the first 16 days of coincident observation. On September 14, 2015, the Advanced LIGO detectors observed a transient gravitational-wave signal determined to be the coalescence of two black holes B. P. Abbott et al., Phys. Rev. Lett. 116, 061102 (2016), launching the era of gravitational-wave astronomy. The event, GW150914, was observed with a combined signal-to-noise ratio of 24 in coincidence by the two detectors. Here, we present the main features of the detectors that enabled this observation. At full sensitivity, the Advanced LIGO detectors are designed to deliver another factor of 3 improvement in the signal-to-noise ratio for binary black hole systems similar in mass to GW150914.
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