Introduction Bucur, Maria; Dalakoura, Katerina; Daskalova, Krassimira ...
Aspasia (New York, N.Y.),
01/2022, Letnik:
16
Journal Article
Recenzirano
This Forum introduces an innovative topic: the short but rich story of the local network of Eastern European feminists, the Little Entente of Women (LEW), which so far has attracted little attention ...among historians working on the region. The four authors present their analysis through the prism of entangled history. The introduction contextualizes the creation and activities of the LEW by providing background information about the post-World War I period, the tensions and struggles between the revisionist and antirevisionist states, and the entanglements between feminist and national goals and between nationalism and internationalism among women's movements and feminisms at the time.
Elimination voltammetry with linear scan (EVLS) was used for the study of the anodic dissolution process of iron microparticles immobilized on paraffin-impregnated graphite electrode. This process ...was investigated in acetate buffer solutions in the range of pH 4 to 6 and the effect of chloride ions was evaluated. It was found that the anodic dissolution process of iron powder proceeded in two peaks with different pH and KCl-dependent characterizations. Both the more negative process at about −300 mV and the positive process at about 1,200 mV are influenced by chloride and hydroxyl ions. Chloride ions incorporate into the intermediate species and form more soluble species in the passivation layer, leading to its degradation. Detailed information about the processes was provided by the EVLS functions conserving diffusion current components. The mechanism of anodic dissolution of iron powder in acetate solutions representing passive ions and chloride ions appearing in the role of corrosion activators was discussed.
Quercetin is one of the best known flavonoids being present in a variety of fruits and vegetables. It has cardioprotective, anticarcinogenic, antioxidant, anti-inflammatory and antiapoptotic ...properties. Some studies suggest that quercetin has protective effects on bone. However, its influence on qualitative and quantitative histological characteristics of compact bone is still unknown. In our study, 12 clinically healthy five-month-old female rabbits were divided into four groups of three animals each. Quercetin was applied intramuscularly in various concentrations; 10 µg/kg body weight (bw) in the E1 group, 100 µg/kg bw in the E2 group, and 1000 µg/kg bw in the E3 group for 90 days, 3 times per week. Three rabbits without exposure to quercetin served as a control (C) group. Differences in femoral bone microstructure among groups were evaluated.
Qualitative histological characteristics of compact bone differed between rabbits from the E1 and E2 groups. Primary vascular longitudinal bone tissue was not found in some areas near the endosteal surface due to increased endocortical bone resorption. In addition, periosteal border of rabbits from the E1 group was composed of a thicker layer of primary vascular longitudinal bone tissue than in the other groups. In all groups of rabbits administered quercetin, a lower density of secondary osteons was observed. Histomorphometrical evaluations showed significantly decreased sizes of the primary osteons' vascular canals in individuals from the E1 and E2 groups. Secondary osteons were significantly smaller in rabbits from the E1, E2, E3 groups when compared to the C group. Cortical bone thickness was significantly increased in females from the E1 and E2 groups.
The results indicate that quercetin has not only a positive dose-response on qualitative and quantitative histological characteristics of the compact bone of female rabbits as it would be expected.
Patulin, a toxic mold metabolite, has been found as natural contaminant of processed fruits, most notably apples, apple juices and other apple-based products. A number of adverse health effects in ...humans and animals are associated with patulin intoxication. The current study was performed to analyse possible toxic effects of patulin on femoral bone microstructure in adult rabbits in detail. Fourteen clinically healthy four-month-old rabbits of both sexes (6 males and 8 females) were included in the study. Animals from the experimental groups (group E♂, n = 3; group E♀, n = 4) were injected intramuscularly with patulin at dose 10 μg/kg body weight two times a week for 28 days. The dose of patulin was estimated based on the maximum permitted level of patulin for apple products intended for infants and young children. Three males and four females without patulin administration served as controls (groups C♂ and C♀). Cortical bone thickness and qualitative and quantitative histological characteristics of compact bone tissue were investigated.
Intramuscular applications of patulin significantly increased the thickness of cortical bone in both sexes of rabbits. In patulin-exposed males, an absence of primary vascular longitudinal bone tissue near the endosteal border was observed, which could be associated with intensive bone remodeling. Femoral diaphyses of females displayed a lower number of secondary osteons in the middle part of the substantia compacta, and occurrence of the osteons near the periosteum. This could indicate alterations in bone turnover. Histomorphometrical evaluations showed significantly increased sizes of the primary osteons' vascular canals (P < 0.05) in males exposed to patulin possibly due to mycotoxin-induced increased levels of testosterone.
This study demonstrates significant impact of intramuscular application of patulin on bone microstructure in adult rabbits. Moreover, we have found that the effects of patulin on qualitative and quantitative histological characteristics of compact bone are sex-dependent.
The pathogenesis of coxsackie B virus (CVB) infections is generally studied in mice by intraperitoneal (i.p.) injection, whereas the gastrointestinal tract is the natural porte d'entrée in humans. ...The present study was undertaken to compare systematically the influence of infection route on morbidity and pathology. Swiss Albino mice were infected with CVB3 (Nancy) at different doses (5 x 10(3), 5 x 10(5), 5 x 10(7), 5 x 10(9) TCID50), given either i.p. or orally. Virus could be isolated from several organs (heart, spleen and pancreas), indicating systemic infection, irrespective of the infection route. Virus titres were 1-2 logs higher after i.p. infection, but kinetics were largely independent of infection route. Organs became negative for virus isolation after 21 days, with the exception of spleen tissue, which remained positive for up to 49 days. Thereafter, virus was detected only by immunohistochemistry and PCR up to 98 days post-infection (oral route). Histopathology showed mild inflammation and necrosis in heart tissue of all mice during the acute phase, with repair at later stages. Strikingly, pancreatic lesions were confined to the exocrine pancreas and observed only after i.p. infection. Under all experimental conditions, the pancreatic islets were spared. In contrast, immunohistochemistry showed the presence of viral VP1, protein 3A and alpha interferon (IFN-alpha) in exocrine as well as endocrine pancreas of all mice, irrespective of route and dose of infection. It is concluded that infection via the oral route protects the pancreas from damage, but not from infection, a process in which IFN-alpha is not the only factor involved.
SAFETY OF DELICACY PRODUCTS IN TRADE NETWORK Lopasovský, Lubomír; Kovácová, Eva; Kunová, Simona ...
Journal of microbiology, biotechnology and food sciences,
01/2013
Special Issue 1 - Part A
Journal Article
Odprti dostop
The aim of this study was evaluation of microbiological quality of delicate products in Slovakia during years 2007 - 2011. In this study 14 834 samples were collected and 1223 (8.24 %) samples did ...not comply with microbiological criteria. Coliform bacteria were detected in 618 samples (4.17 %), E. coli was detected in 298 samples (2.01 %). Yeasts and filamentous microscopic fungi were detected in 397 samples (2.68 %). Listeria monocytogenes was detected in 41 samples (0.28 %), Staphylococcus aureus in 12 samples (0.08 %), Bacillus cereus in 13 samples (0.09 %), Salmonella spp. in 4 samples (0.03 %) and sulphidreduces clostridia were not detected in all samples. Coliform bacteria indicate poor operational hygiene.
PDF
