Drought intensity and frequency have increased in recent years, which poses significant threats to forest ecosystems, especially in the context of global climate change. This paper is aimed at ...summarizing the current state of research and global development trends regarding drought-induced tree mortality mechanisms in tree physiology. Developing a robust literature foundation will facilitate in-depth research and foster the exchange of knowledge related to this subject. A literature review was conducted using tools such as VOSviewer, CiteSpace, and the Bibliometrix R-package to review the literature from the Web of Science’s core database from 1985 to 2023. We intend to determine the current state and evolution of global research on drought-induced tree mortality mechanisms. The results reveal that research on drought-induced tree mortality mechanisms gained momentum predominantly in the last two decades, with a marked surge post-2012. The United States is the epicenter of research, leading the global scientific community with its preeminence in publication volume, citation rates, and the scope of collaborative networks, with China in close pursuit. Tree Physiology stands out as the leading journal in this domain, boasting 129 articles. McDowell NG emerges as the most prolific author, with an H-index of 41, underscoring his influence in the field. There is a clear upward trend in collaborations spanning authors, journals, research institutions, and countries. The analysis of frequently cited keywords and topic evolution suggests that drought and tree mortality will likely remain key research areas for the foreseeable future. The future of research on drought-induced tree mortality mechanisms in physiology is promising, as it emphasizes multidisciplinary approaches and global collaborations.
Qing-Fei-Pai-Du decoction (QFPDD) is a Chinese medicine compound formula recommended for combating corona virus disease 2019 (COVID-19) by National Health Commission of the People’s Republic of ...China. The latest clinical study showed that early treatment with QFPDD was associated with favorable outcomes for patient recovery, viral shedding, hospital stay, and course of the disease. However, the effective constituents of QFPDD remain unclear. In this study, an UHPLC-Q-Orbitrap HRMS based method was developed to identify the chemical constituents in QFPDD and the absorbed prototypes as well as the metabolites in mice serum and tissues following oral administration of QFPDD. A total of 405 chemicals, including 40 kinds of alkaloids, 162 kinds of flavonoids, 44 kinds of organic acids, 71 kinds of triterpene saponins and 88 kinds of other compounds in the water extract of QFPDD were tentatively identified via comparison with the retention times and MS/MS spectra of the standards or refereed by literature. With the help of the standards and in vitro metabolites, 195 chemical components (including 104 prototypes and 91 metabolites) were identified in mice serum after oral administration of QFPDD. In addition, 165, 177, 112, 120, 44, 53 constituents were identified in the lung, liver, heart, kidney, brain, and spleen of QFPDD-treated mice, respectively. These findings provided key information and guidance for further investigation on the pharmacologically active substances and clinical applications of QFPDD.
Acculturation could cause grave health consequences in international students. However, there is a shortage of research into how acculturative stress might affect international students' quality of ...life in light of their academic standing and experience. The lack of research is particularly pronounced among Chinese international students, representing the largest body of international students studying in the United States (U.S.). Thus, to bridge the research gap, this study aims to examine the interplay between international students' acculturative stress, academic standing, and quality of life among a nationally representative sample of Chinese international students studying in the United States.
An online survey that gauges Chinese international students' levels of acculturative stress, academic standing, and quality of life was developed. Over 350 higher education institutions across the United States were approached, including public universities, private universities, and community colleges, among which approximately 220 institutions responded positively and supported survey distribution. A total of 751 students completed the survey. Multiple regression analyses were carried out to examine the associations between students' acculturative stress, academic standing, and quality of life.
Findings reveal that acculturative stress negatively affects all four domains of Chinese international students' quality of life, irrespective of their academic standing. Data analyses also show that compared to master's and doctoral students, undergraduates experience the highest levels of acculturative stress. Furthermore, a significant difference emerged among undergraduate and doctoral international students' acculturative stress levels, but not among undergraduate and master's students, or master's and doctoral students.
Our study found that, compared to master's and doctoral students, undergraduates had more significant acculturative stress associated with lower levels of quality of life. This finding highlights the potentially positive role of academic experience - while acculturative stress deteriorates international students' quality of life, students' academic standing and experience could be the protective factor in the equation. Future research could further examine how universities and colleges can capitalize on their academic apparatuses and resources to improve international students' academic performance and students' acculturation experience and quality of life.
Kawasaki disease (KD) is a type of systemic vasculitis that primarily affects children under the age of five years old. For sufferers of KD, intravenous immunoglobulin (IVIG) has been found to ...successfully diminish the occurrence of coronary artery lesions. Anemia is commonly found in KD patients, and we have shown that in appropriately elevated hepcidin levels are related to decreased hemoglobin levels in these patients. In this study, we investigated the time period of anemia and iron metabolism during different stages of KD. A total of 100 patients with KD and 20 control subjects were enrolled in this study for red blood cell and hemoglobin analysis. Furthermore, plasma, urine hepcidin, and plasma IL-6 levels were evaluated using enzyme-linked immunosorbent assay in 20 KD patients and controls. Changes in hemoglobin, plasma iron levels, and total iron binding capacity (TIBC) were also measured in patients with KD. Hemoglobin, iron levels, and TIBC were lower (p < 0.001, p = 0.009, and p < 0.001, respectively) while plasma IL-6 and hepcidin levels (both p < 0.001) were higher in patients with KD than in the controls prior to IVIG administration. Moreover, plasma hepcidin levels were positively and significantly correlated with urine hepcidin levels (p < 0.001) prior to IVIG administration. After IVIG treatment, plasma hepcidin and hemoglobin levels significantly decreased (both p < 0.001). Of particular note was a subsequent gradual increase in hemoglobin levels during the three weeks after IVIG treatment; nevertheless, the hemoglobin levels stayed lower in KD patients than in the controls (p = 0.045). These findings provide a longitudinal study of hemoglobin changes and among the first evidence that hepcidin induces transient anemia and hypoferremia during KD's acute inflammatory phase.
Aggregate is the basic unit of soil structure, which is crucial to the sustainability of soil system functions such as structural stability and Fertility Maintenance. Three Gorges Dam (TGD) has ...extensively led to a dramatic hydrological regime alteration, which may consequently affect various soil physical properties. The aim of this study was to investigate the long-run temporal variation of soil aggregate stability as induced by water-level fluctuations in the riparian zone of the Three Gorges Reservoir (TGR). Sampling plots were established along different elevations considering the interval of 5 m, starting from 150 m to 175 m. A Laser Diffraction based analysis that allows the measurement of soil aggregate stability after the removal of soil organic matter helped to particularly study the effect of external factors on soil aggregate stability of the study area. In addition, wet-sieving method considering the effect of chemical binding agents was used to quantify aggregate stability. The present results indicated a significant increase of Mean Volume Diameter, MVD (p < 0.05) within the study period. Continuous drying-wetting cycles mended soil aggregate stability with a 14.25% increase of the MVD from 2012 to 2016. In the Water-Level Fluctuation Zone (WLFZ), the lower land has predominantly contributed to the increase of soil aggregate stability compared to upper land, with an increase of 62.19% and 37.81% for MVD, 60.88% and 39.12% for D10, 95.34% and 4.66% for D90 at lower and upper elevations, respectively. Sediment deposition below 165 m has precluded a direct effect of water stress on soil aggregates, which certainly declined soil disaggregation. The removal of SOM while analyzing aggregate stability by LD may explain the contradiction between the resulted MVD, and the MWD and GMD. The increase of MWD and GMD was mainly attributed to the increase of SOM with r2 = 0.89 (p < 0.01) and r2 = 0.90 (p < 0.01), while the increase of MVD was highly predicted by the decrease of SOM with r2 = 0.88 (p < 0.01). Since this study presents a remarkable change of soil in the riparian area due to dry-wet cycles, our results may help to deeply understand the soil ecology and environmental changes in the WLFZ.
The characterization of the Contaminant concentration pollution level and source of surface dust heavy metals is imperative that pollution monitoring and control. Surface dust heavy metal data from ...37 cities across China was collated, from which the concentrations of Cu, Cr, Zn, Cd, Ni and Pb were investigated. Results are shown that the average contents of these heavy metals exceed soil background values, indicating that the majority of examined cities have serious pollution and ecological risk. In a certain range of heavy metal content, Zn, Cr and Pb contents are a positive relationship with the amount of motor vehicles and industrial added value. Heavy metal accumulations had exceeded the limits of a natural factor repairing in cities, and the influence of natural factors on heavy metal concentrations was therefore weak.
Abstract Background Previous studies of mostly Western women have reported inconsistent findings on the association between age at menarche and risk of cardiovascular disease (CVD). Little is known ...about the association in China where there has been a large intergenerational decrease in women's mean age at menarche. Methods The China Kadoorie Biobank recruited 302,632 women aged 30–79 (mean 50.5) years in 2004–8 from 10 diverse regional sites across China. During 7 years follow-up, 14,111 incident cases of stroke, 14,093 of coronary heart disease (CHD), and 3200 CVD deaths were reported among 281,491 women who had no prior history of CVD at baseline. Cox regression yielded adjusted hazard ratios (HRs) relating age at menarche to CVD risks. Results The mean (SD) age of menarche was 15.4 (1.9) years, decreasing from 16.2 (2.0) among women born before 1940 to 14.7 (1.6) for those born during the 1960s–1970s. The patterns of association between age at menarche and CVD risk appeared to differ between different birth cohorts, with null associations in older generations but U-shaped or weak positive associations in younger women, especially those born after the 1960s. After minimizing the potential confounding effects from major CVD risk factors, both early and late menarche, compared with menarche at age 13 years, were associated with increased risk of CVD morbidity and mortality, which was more pronounced in younger generations. Conclusion Among Chinese women the associations between age at menarche and risk of CVD differed by birth cohort, suggesting other factors may underpin the association.
Background:
COVID-19 has had a wide impact on the mental health of college students. This study aims to explore the relationship between time perception, risk perception, and the mental health of ...college students during COVID-19 through a questionnaire survey.
Subjects:
One thousand two hundred and eighteen college students, 449 male and 769 female, who studied online during the COVID-19 epidemic were selected.
Methods:
Time Perception Scale, Risk Perception Scale, and SCL-90 were used to investigate the relationship using correlation analysis.
Results:
During the COVID-19 period, mental health problems of college students were widespread, and 65.93% of college students reported moderate to severe mental health problems. The correlation analysis showed that risk perception, time perception, and the mental health of college students were significantly related. Risk perception played a partial mediating role between present enjoyment and mental health, and risk perception played a partial mediating role between future time perception and mental health.
Conclusion:
In the case of sudden public crises, we should pay close attention to the mental health of college students, adjust their attitude toward the present and the future, and pay attention to their perception of risk so as to improve their mental health level under crisis.
Acute lung injury (ALI), instilled by lipopolysaccharide (LPS), is a severe illness with excessive mortality and has no specific treatment strategy. Luteolin is an anti-inflammatory flavonoid and ...widely distributed in the plants. Pretreatment with luteolin inhibited LPS-induced histological changes of ALI and lung tissue edema. In addition, LPS-induced inflammatory responses, including increased vascular permeability, tumor necrosis factor (TNF)-α and interleukin (IL)-6 production, and expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), were also reduced by luteolin in a concentration-dependent manner. Furthermore, luteolin suppressed activation of NFκB and its upstream molecular factor, Akt. These results suggest that the protection mechanism of luteolin is by inhibition of NFκB activation possibly via Akt.
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