This study aimed to determine the efficacy and safety of intralesional betamethasone in erosive oral lichen planus and to evaluate relapse of erosion.
Patients were randomly assigned to the ...experimental group (1.4 mg intralesional betamethasone) or to the control group (8 mg intralesional triamcinolone acetonide), and they received injections once a week for 2 weeks. Erosive area and pain level were assessed on days 1, 7 ± 2, and 14 ± 2. If the lesion disappeared, any recurrence within the following 3 months was recorded.
Twenty-nine participants in the experimental group and 30 in the control group completed the protocol. Healed percentage was higher with betamethasone (93.1%) than with triamcinolone (66.7%; P = .02), and final reduction in erosion area was greater in the experimental group (21.276 ± 21.064 mm(2)) than in the control group (11.5 ± 12.95 mm(2); P = .02). Reduction in pain level did not differ between groups. The proportion of participants with recurrent erosions was significantly lower in the experimental group (14.8%) than in the control group (45%; P = .04).
Intralesional betamethasone may be used in the topical treatment of erosive oral lichen planus.
Purpose To evaluate bone formation after marsupialization of odontogenic keratocysts (keratocystic odontogenic tumors) of the mandible. Patients and Methods A total of 53 patients with mandibular ...odontogenic keratocysts underwent marsupialization. Clinical and radiographic examinations were done at 1, 3, and 6 months postoperatively. The bone density of the cyst site was measured on the panoramic radiographs using the Digora. The volume of the cyst was measured by injection of saline solution into the cyst cavity. Student t test and Spearman's rank correlation were used for statistical analysis. Results Healing was uneventful in all patients. The diameter of the cysts was 4.1 to 11.0 cm (average 5.4). The panoramic radiographs showed a continuous increase in bone density of the cystic area, with a 22.42% increase at 1 month, 46.07% at 3 months, and 64.69% at 6 months postoperatively compared with the preoperative values. The decrease in cyst volume was 19.05% at 1 month, 55.62% at 3 months, and 79.67% at 6 months postoperatively. The increase in bone density and decrease in cyst volume were more significant in the first 3 months than in second 3 months ( P < .01). The increase in bone density correlated inversely with the decrease in the cyst volume ( P < .01). Conclusion Bone regeneration can occur more rapidly in large mandibular odontogenic keratocysts after marsupialization with drainage by a cyst plug. After 3 months, secondary enucleation of the cyst can be performed.
Purpose The purpose of this study was to evaluate and compare the demographic characteristics of maxillofacial fractures between women and men in China. Patients and Methods The sample was composed ...of all patients who sustained maxillofacial fractures during a 10-year period (2000 through 2009). Incidences, age distributions, etiologies, fracture patterns, associated injuries, and occupation distributions were recorded and analyzed. Data analysis included the χ2 test, the Fisher exact test, and the t test. A P value less than .05 was considered significant. Results There were 1,131 patients (881 male and 250 female) who sustained maxillofacial fractures, with a male-to-female ratio of 3.5:1. Male patients sustained injuries most frequently during the autumn ( P = .048), whereas female patients sustained more maxillofacial injuries during the summer ( P = .006). Men sustained motorcycle ( P = .023) and assault-related accidents ( P = .036) more frequently than women, whereas women were more frequently injured in bicycle-related accidents ( P < .001) or falling while at ground level ( P = .001) than men. Women presented more frequently with condylar fracture than men ( P = .028), whereas men were more prone to symphysis fractures than women ( P = .037). For drivers, only men were involved ( P = .001). Male workers sustained maxillofacial fractures more frequently than female workers ( P < .001). Female children, students, and company staff were more prone to maxillofacial fractures than their male counterparts ( P = .010, P = .004, and P = .044 respectively). Conclusions The demographic characteristics of maxillofacial fractures in female patients considerably differ from those in male patients.
Purpose To evaluate the commissural symmetry and commissural migration among patients with unilateral transverse facial cleft. Patients and Methods From 2006 to 2009, 31 patients with unilateral ...transverse facial cleft were repaired with superiorly based vermillion-mucosal flap and orbicularis oris reconstruction. Linear closure and superiorly rotated and inferiorly rotated Z -plasty were randomly chosen for skin closure. An anthropometric method was used immediately after the repair and at the follow-up examination to evaluate the commissural symmetry in both horizontal and vertical directions. Results A total of 21 patients was followed-up for 19 months on average. Satisfactory horizontal symmetry was obtained right after surgery; however, the new commissure was generally lower than the unaffected commissure. At the follow-up examination, no significant lateral commissural displacement was observed; however, the commissural droop on the cleft side became more noticeable. Conclusions The anthropometric method used was convenient and reliable for facial symmetry analysis. Rectangular vermillion-mucosal flap and proper muscle reconstruction could prevent the lateral commissural migration caused by skin scar contracture. Both horizontal and vertical symmetry should be considered for macrostomia repair.
Keratocystic odontogenic tumor (KCOT) is a benign intraosseous neoplasm of odontogenic origin with high recurrence rates and tendency to invade adjacent tissue. Most recurrences occur in the first 5 ...years after surgery and are usually located at the site of the primary tumor in the jaws. We report a rare case of KCOT which recurred in the masseter muscle 14 years after segmental mandibulectomy and autogenous frozen lesional mandible reimplantation. The patient had undergone enucleation of KCOT in the right mandible 20 years before segmental mandibulectomy. This case could further demonstrate the aggressive behavior of KCOT.
The aim of this study was to explore the bone-soft tissue relationships around the nasolabial area in uncorrected secondary unilateral cleft nose deformities.
Measurements taken from photographs and ...cone-beam computerized tomography (CBCT) results were derived and paired up to represent the deformity features of bone and soft tissue, respectively.
All soft tissue measurements were significantly smaller than the corresponding bone measurements. Various bone-soft tissue correlation patterns were observed in different measurement pairs.
The adopted photography-CBCT combined measurement method appeared to be reliable in evaluating the hard-soft tissue relationships in the nasolabial area. In unoperated unilateral cleft nose deformities, bony deformities would decide the soft tissue contours, and soft tissue in turn could camouflage the underlying bone deformities in various patterns and scale, making the external configuration less deformed than its bone basis.