The effect of a Cu2O substrate on the photoinduced alteration of the hydrophilicity of TiO2 and ZnO surfaces was studied. It was demonstrated that the formation of heterostructures Cu2O/TiO2 and ...Cu2O/ZnO strongly changed the direction of the photoinduced alteration of surface hydrophilicity: while both TiO2 and ZnO demonstrate surface transition to superhydrophilic state under UV irradiation and no significant alteration of the surface hydrophilicity under visible light irradiation, the formation of Cu2O/TiO2 and Cu2O/ZnO heterostructures resulted in photoinduced decay of the surface hydrophilicity caused by both UV and visible light irradiation. All observed photoinduced changes of the surface hydrophilicity were compared and analyzed in terms of photoinduced alteration of the surface free energy and its polar and dispersive components. Alteration of the photoinduced hydrophilic behavior of TiO2 and ZnO surfaces caused by formation of the corresponding heterostructures with Cu2O are explained within the mechanism of electron transfer and increasing of the electron concentration on the TiO2 and ZnO surfaces.
Russia and most countries of the world are currently facing pressures on their health services because of the growing number of diseases associated with unhealthy lifestyles: type 2 diabetes, ...obesity, non-alcoholic fatty liver disease, etc. Lifestyle modification is the first prerequisite in the treatment of non-alcoholic fatty liver disease and other diseases associated with unhealthy lifestyle. The use of lactitol provides the opportunity to make this process more effective, as it is able to increase the production of butyrate, reduce the damage to the intestine barrier structure, and interact with sweet-taste receptors. Lactitol has a low glycaemic index, it is not absorbed in the intestine and is fermented like dietary fibres. The results of the studies showed that the metabolic response to this drug corresponds to a lower increase in plasma glucose, insulin and C-peptide levels compared to the use of glucose in healthy, non-obese men. It has been shown through various experiments in animals and in humans that lactitol also reduces the plasma triglyceride levels, probably due to reduced triglyceride absorption as a result of accelerated transit of intestinal contents. An important property of the drug is its ability to increase the glucagon-like peptide-1 (GLP-1) and PYY levels, which is accompanied by delayed gastric emptying and reduced hunger, which is essential in the treatment of obesity, type 2 diabetes mellitus and non-alcoholic fatty liver disease. A 120-day randomized controlled trial was conducted to assess the efficacy, safety, and tolerability of lactitol in 139 patients with nonalcoholic fatty liver disease. Twice-daily administration of lactitol 6 g in addition to lifestyle modification events has been shown to increase their efficacy expressed as a significant decrease in ALT levels and an increase in the AST/ALT ratio compared to control subjects. Lactitol can be considered as a metabolic corrector and used in the treatment of diseases associated with an unhealthy lifestyle.
Introduction. The search for simple and informative markers for predicting positive outcomes in patients with liver cirrhosis (LC) does not affect its relevance. Aim. To study the possibility of ...using the “neutrophil to lymphocyte ratio” indicator as a predictor of development of LC complications and death. Materials and methods. For a retrospective clinical study, 225 case histories of patients with LC were selected from 2008 to 2018. Three groups were formed from them: group 1: patients with LC class A according to Child- Pugh (24n); Group 2: patients with LC class B and C according to Child- Pugh (201n); and group 3: healthy individuals (50n). A correlation analysis of the NLR indicator with the Child- Pugh and MELD scales was carried out. The prognostic value of NLR in the development of complications and death was analyzed. Results. Patients with LC had statistically significantly higher values of NLR compared to healthy individuals (p < 0.001). NLR had a statistically significant positive correlation with the Child- Pugh (p < 0.001) and MELD (p < 0.001) scales. NLR is a statistically significant predictor of the development of complications in patients with LC (p = 0.003). A NLR value > 2.3 had a sensitivity of 0.97 95% CI: 0.92; 0.99 and specificity 0.19 95% CI: 0.11; 0.29. NLR statistically significantly correlated with the number of complications of LC (p<0.001) and served as a statistically significant predictor of death (p<0.001). A NLR value > 4.5 had a sensitivity of 0.24 95% CI: 0.15; 0.36 and specificity 0.97 95% CI: 0.92; 0.99. Conclusion. An NLR value of more than 2.3 increases the risk of complications in patients with LC, and an NLR value of more than 4.5 increases the risk of death.
The study of Ibn Taymiyyah’s ideas on haram and halal in Islam remains relevant for understanding Islamic jurisprudence, ethics, cultural identity and contemporary issues. The purpose of the paper is ...to analyze Ibn Taymiyyah’s works and identify his most important concepts for the Muslim community. The methods of analyzing fatwas, written by Ibn Taymiyyah, and methods of interpreting and comparing the concepts of forbidden and permitted in Islam were used to achieve the purpose of the study. The main conclusion of the study is that Ibn Taymiyyah was known for his research in Islamic law, theology and morality. The figure had conservative views, and due to his own reformist ideas, he was repeatedly convicted. Despite this, he criticized traditional teachings about Islam and supported the need to reform some aspects of Islamic practice. Ibn Taymiyyah attached great importance to the examination of Prophet Muhammad’s Quran and Sunnah to understand what is forbidden and allowed in various areas of Muslim life. He stressed the importance of a healthy diet, the need to follow Islamic principles in financial matters and the preservation of dignity and respectful behavior in all aspects of life.
Resumo: O estudo das ideias de Ibn Taymiyyah sobre o haram e o halal, no Islã, continua a ser relevante para a compreensão da jurisprudência islâmica, da ética, da identidade cultural e das questões contemporâneas. O objetivo do artigo é analisar as obras de Ibn Taymiyyah e identificar seus conceitos mais importantes para a comunidade muçulmana. Os métodos de análise das fatwas escritas por Ibn Taymiyyah e os métodos de interpretação e comparação dos conceitos de proibido e permitido, no Islã, foram usados para atingir o objetivo do estudo. A principal conclusão da pesquisa é que Ibn Taymiyyah era conhecido por suas pesquisas em lei islâmica, teologia e moralidade. Ele tinha visões conservadoras e, devido às suas próprias ideias reformistas, foi repetidamente condenado. Apesar disso, ele criticou os ensinamentos tradicionais sobre o Islã e apoiou a necessidade de reformar alguns aspectos da prática islâmica. Ibn Taymiyyah atribuiu grande importância ao exame do Alcorão e da Sunnah do Profeta Muhammad, a fim de entender o que é proibido e permitido, em várias áreas da vida muçulmana. Ele enfatizou a importância de uma dieta saudável, a necessidade de seguir os princípios islâmicos em questões financeiras e a preservação da dignidade e do comportamento respeitoso, em todos os aspectos da vida.
The increasing importance of business communication has been widely discussed in recent years. English and German have become the languages of international communication. The mastering of languages, ...which are the definite means of communication with the peoples of other countries is getting a greater significance in our modern society. This work aims to study the architectonics of English and German business letters, identify the function of "black" and "white" spaces in business correspondence, and a comparative analysis of English and Russian business letters.
This review focuses on the most current information on the pathogenesis, diagnosis and treatment of sarcopenia and malnutrition in patients with liver disease. Sarcopenia and malnutrition are ...common complications of liver diseases. Liver cirrhosis, as a stage of the pathological process, serves as the main predisposing factor for the development of malnutrition and sarcopenia. The frequency of sarcopenia in liver cirrhosis is 30–50% and reaches 100% in decompensated patients. The main pathogenetic links are: impaired proteostasis of skeletal muscles, systemic inflammation and changes in gut microbiota. In recent years, enough data have been accumulated to consider these conditions as a prognostically unfavorable factor in patients with liver cirrhosis of various etiologies, affecting their quality of life and survival, as well as worsening the out-comes of transplantation. This dictates the necessity to define unified approaches to diagnostics and correction of these conditions. Currently, tests are used for diagnosis, which allow to assess muscle strength and function. Muscle mass is assessed using instrumental methods by measuring individual muscles and calculating skeletal muscle indices. In patients with liver cirrhosis and concomitant sarcopenia and malnutrition, nutritional and lifestyle modification strategies are applicable for correction in addition to therapy aimed at elimination of the etiologic factor. The aim of the review is to evaluate the problems of diagnosis and effective treatment of malnutrition and sarcopenia in patients with liver disease based on literature data. The article presents an overview of the main strategies for the approach, diagnosis and correction of these conditions.
Here, we report the results of comparative studies of the photostimulated hydrophilic behavior of heterostructured TiO2/BiVO4 and ZnO/BiVO4, and monocomponent TiO2 and ZnO nanocoating surfaces. The ...chemical composition and morphology of the synthesized nanocoatings were characterized by XPS, SEM, and AFM methods. The electronic energy structure of the heterostructure components (band gap, top of the valence band, bottom of the conduction band, and Fermi level position) was determined on the basis of experimental results obtained by XPS, UV-V absorption spectroscopy and Kelvin probe methods. According to their electronic energy structure, the ZnO/BiVO4 and TiO2/BiVO4 heterostructures correspond to type I and type II heterostructures, respectively. The difference in the type of heterostructures causes the difference in the charge transfer behavior at heterojunctions: the type II TiO2/BiVO4 heterostructure favors and the type I ZnO/BiVO4 heterostructure prevents the photogenerated hole transfer from BiVO4 to the outer layer of the corresponding metal oxide. The results of the comparative studies show that the interaction of the photogenerated holes with surface hydroxy-hydrated multilayers is responsible for the superhydrophilic surface conversion accompanying the increase of the surface free energy and work function. The formation of the type II heterostructure leads to the spectral sensitization of the photostimulated surface superhydrophilic conversion.
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