Los elementos que huyen de la mímesis en el medio videolúdico se enraízan profundamente en las concepciones estéticas que, estructuralmente, presentan un patrón muy similar a los desafíos ...conceptuales que supusieron las vanguardias históricas hace ya un siglo.
Análisis de estándares para la web móvil Rodríguez, Rocío Andrea; Vera, Pablo Martín; Martinez, María Roxana ...
RECIBE,
03/2021, Letnik:
9, Številka:
2
Journal Article
Odprti dostop
El W3C es un consorcio internacional que establece estándares para la web. Eso estándares, llamados recomendaciones, son tomados como puntos de partida e implementados por los navegadores web, ...permitiendo que los desarrolladores lo utilicen. Estas recomendaciones son muy importantes para la portabilidad permitiendo que cualquier usuario utilice una aplicación web con todas sus características sin importar el navegador que posea. Este artículo presenta un relevamiento de las recomendaciones del W3C realizando una clasificación de acuerdo al grado de madurez alcanzado dentro de las categorías propuestas por la misma organización. Sin perder de vista la importancia de la estandarización llevada a cabo por el W3C, se presenta un caso de estudio que evidencia problemas en la evolución entre las diferentes etapas. Este artículo considera las siguientes cuestiones ¿Es confiable tomar como base e implementar una tecnología que aún no se ha convertido en recomendación, pero está cerca de serlo? ¿Cuánto tiempo debe un desarrollador esperar para poder usar una nueva tecnología y usarla en sus desarrollos? El caso de estudio propuesto dará respuesta a estas preguntas.
RESUMEN Esta investigación permite conocer cómo conceptualizan el patrimonio los estudiantes del Grado en Maestro de Primaria de la Universidad de Valladolid y determinar el modo en que los vínculos ...se construyen e intervienen en la generación de identidades. Se utilizaron N = 472 textos publicados en el entorno digital www.pesonasypatrimonios.com entre los años 2018 y 2021. En los análisis, se emplearon técnicas de minería de textos. Los resultados confirmaron el carácter opuesto entre los modelos de conceptualización histórico e identitario. Se constató la presencia de términos semánticos asociados a las cinco dimensiones del patrimonio y a todos los verbos contenidos en la SPP, si bien se observó que la conceptualización ligada al monumento mantiene todavía una fuerte presencia.
RESUMO Esta pesquisa permite-nos conhecer como os alunos do Curso de Licenciatura da Universidade de Valladolid conceptualizam o patrimônio e determinam a forma como os vínculos se constroem e intervêm na geração das identidades. Foram utilizados N = 472 textos publicados no meio digital www.pesonasypatrimonios.com entre os anos 2018 e 2021. Foram utilizadas técnicas de mineração de texto nas análises. Os resultados confirmaram o caráter oposto entre os modelos de conceituação histórica e identitária. Verificou-se a presença de termos semânticos associados às cinco dimensões do património e a todos os verbos contidos no SPP, mas a conceitualização ligada ao monumento ainda mantenha uma presença forte.
ABSTRACT The research aim is to know how the students of the Primary Teacher Degree at the University of Valladolid conceptualize heritage and determine the way in which links are built and intervened on the generation of identities. N = 472 texts published in the digital environment www.pesonasypatrimonios.com between 2018 and 2021 were used. Text mining techniques were used to analyze the data. The results confirm the opposite character between the historical and identity conceptualization models. The presence of semantic terms associated with the five dimensions of heritage and all the verbs contained in the SPP were confirmed, although the conceptualization linked to the monument still maintains a strong presence.
To assess the association between having suffered a fall in the month prior to interview and long-term overall survival in nursing-home residents.
Retrospective cohort study conducting an overall ...survival follow-up of 689 representative nursing-home residents from Madrid, Spain. Residents lived in three types of facilities: public, subsidized and private and its information was collected by interviewing the residents, caregivers and/or facility physicians. Residents contributed to follow-up time from their baseline interviews until death or being censored at the end of the 5-year follow-up period. The association between suffering a fall during the month prior to interview and long-term overall survival was analyzed using Cox proportional hazards models. To adjust for potential confounders we used progressive adjusted models. We then repeated the analyses with severity of the fall (no fall, non-severe, severe) as the main independent variable.
After a 2408 person-year follow-up (median 4.5 years), 372 participants had died. In fully-adjusted models, residents who had suffered any kind of fall in the previous month showed virtually the same survival rates compared to non-fallers (hazard ratio (HR) = 1.03; 95% CI = 0.75-1.40). There was a weak graded relationship between increased fall severity and survival rates for the non-severe fall group (HR = 0.92; 95% CI = 0.58-1.45) and the severe fall group (HR = 1.36; 95% CI = 0.73-2.53) compared with residents who had not suffered any kind of fall. The hazard ratios for severe falls were higher in men, residents with less comorbidity, fewer medications, and those functionally independent.
We found no associations between having suffered a fall in the month prior to interview and long-term survival; neither did we find a marked association when severity of fall was accounted for in the whole population. In some subgroups, however, the results merit further scrutiny.
Background
Non‐motor symptoms (NMS) are integral to Parkinson's Disease (PD) and management remains a challenge. Safinamide is a novel molecule in relation to addressing NMS due to its multifocal ...mechanism of action with both dopaminergic and non‐dopaminergic properties.
Objective
To investigate the efficacy of safinamide on NMS and its burden in PD patients with motor fluctuations after 6 months of treatment.
Methods
This observational, multicenter, open‐label, pilot study assessed a wide range of NMS using the following rating scales, NMSS (non‐motor symptom scale), KPPS (King's PD pain scale), HADS (hospital anxiety and depression scale), PDQ‐8 (Parkinson's disease quality of life questionnaire), and PDSS‐2 (Parkinson's disease sleep scale), EuroQol‐5D 3 level version (EQ‐5D‐3L), CGI‐I (clinical global impression of improvement), and PGI‐C (patient global impression of change). Motor examination using UPDRS part III (Unified Parkinson's disease rating scale, motor examination), UPDRS IV (complications of therapy) and Hoehn and Yahr staging were also obtained.
Results
27 patients were included in the analysis and were evaluated at baseline and ≥ 6 months after safinamide treatment. 26 patients had a daily maintenance dose of 100 mg and 1 patient a daily dose of 50 mg. Significant improvements in UPDRS IV, KPPS item 5 (region‐specific “off” dystonia), KPPS domain 3 (items 4–6, fluctuation related pain) and KPPS total score were observed after treatment with safinamide, while maintaining stable dopaminergic medication. No statistically significant differences were found in NMSS, HADS, PDSS‐2, EQ‐5D‐3L, and PDQ‐8 after treatment.
Conclusions
Our results suggest that safinamide may have a beneficial effect on pain, a key unmet need in fluctuating PD patients.
In this observational prospective study we investigate the effects of safinamide on non‐motor symptoms in patients with fluctuating Parkinson's disease. Our main finding is a significant improvement in UPDRS IV and pain as measured by the KPPS.
Irrigation with reclaimed water is becoming a common practice in arid- and semi-arid regions as a consequence of structural water resource scarcity. This practice can lead to contamination of the ...vadose zone if sewage-derived contaminants are not removed properly. In the current work, we have characterized soils from the Guadalete River basin (SW Spain), which are often irrigated with reclaimed water from a nearby wastewater treatment plant and amended using sludge. Physico-chemical, mineralogical and hydraulic properties were measured in soil samples from this area (from surface up to 2m depth). Emerging contaminants (synthetic surfactants and pharmaceutically active compounds, or PhACs) were also determined. Synthetic surfactants, widely used in personal care products (PCPs), were found in a wide range of concentrations: 73–1300μgkg−1 for linear alkylbenzene sulfonates (LAS), 120–496μgkg−1 for alkyl ethoxysulfates (AES), 19–1090μgkg−1 for alcohol polyethoxylates (AEOs), and 155–280μgkg−1 for nonylphenol polyethoxylates (NPEOs). The presence of surfactant homologues with longer alkyl chains was predominant due to their sorption capacity. A positive correlation was found between LAS and AEOs and soil organic carbon and clay content, respectively. Out of 64PhACs analyzed, only 7 were detected occasionally (diclofenac, metoprolol, fenofibrate, carbamazepine, clarithromycin, famotidine and hydrochlorothiazide), always at very low concentrations (from 0.1 to 1.3μgkg−1).
is a singular halophyte that has been shown to have anti-inflammatory, antioxidant, and allelopathic properties. In the work presented herein, we have characterized its inflorescences hydromethanolic ...extract and assessed its antifungal activity for the pre- and postharvest management of tomato crop diseases. Gas chromatography-mass spectrometry characterization of the extract showed that 4-ethenyl-1,3-benzenediol, 2,3-dihydro-benzofuran, quinic acid, 3,5-dihydroxy-6,7,8-trimethoxy-2-phenyl-4H-1-benzopyran-4-one, 1,6-anhydro-
-D-glucopyranose, catechol, scopoletin, and maltol were the main constituents. The co-occurrence of pyranones, benzenediols, and quinic acids as phytoconstituents of
extract resulted in promising in vitro minimum inhibitory concentrations of 500, 375, 500, 187.5, 187.5, and 375 μg·mL
against mycelia of
,
f. sp.
, and
, respectively. Further, to assess the potential of
inflorescence extract for postharvest tomato crop protection, ex situ tests were conducted against
, obtaining high protection at a dose of 750 μg·mL
. Taking into consideration that the demonstrated activity is among the highest reported to date for plant extracts and comparable to that of the synthetic fungicides tested as positive controls,
inflorescence extract may be put forward as a promising biorational and may deserve further testing in field-scale studies.
In the last few decades, there has been a growing interest in understanding the behavior of personal care products (PCPs) in the aquatic environment. In this regard, the aim of this study is to ...estimate the accumulation and effects of four PCPs within the clam
Ruditapes philippinarum
. The PCPs selected were triclosan, OTNE, benzophenone-3, and octocrylene. A progressive uptake was observed and maximum concentrations in tissues were reached at the end of the exposure phase, up to levels of 0.68 µg g
−1
, 24 µg g
−1
, 0.81 µg g
−1
, and 1.52 µg g
−1
for OTNE, BP-3, OC, and TCS, respectively. After the PCP post-exposure period, the removal percentages were higher than 65%. The estimated logarithm bioconcentration factor ranged from 3.34 to 2.93, in concordance with the lipophobicity of each substance. No lethal effects were found although significant changes were observed for ethoxyresorufin O-demethylase activity, glutathione S-transferase activity, lipid peroxidation, and DNA damage.
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