Growing use of remote sensing in scientific and forensic analysis requires collecting large quantities of signature data from a variety of sensors requiring various techniques as well as careful ...consideration of environmental conditions. The quantity of collected signature data continues to grow rapidly and the challenge of storing, classifying, searching and exchanging of signatures has significantly increased. For example, the Joint Improvised Explosive Device Defeat Organization (JIEDDO) Integrated Signatures Program (ISP) has collected approximately one million IR, Raman, Mass Spec, RF and other signatures that must be effectively managed. This paper discusses approaches for standardizing metadata across different phenomenology, data interchange formats, unique identification of signatures, signature quality metrics, facilitating third party analysis tools and large signature library management and distribution. Each of these items must be considered when developing a standard for collected signatures.
Anticipate Evolving Lending Requirements - Consider Multiple Options In many cases, franchise owners have been able to delay tough conversations with capital partners as short-term liquidity has been ...enhanced through PPP loans and deferrals from franchisors, landlords, lenders and other vendors. Depending on the concept, we anticipate increasing capital requirements and facility upgrades as brands and operators focus on refning their business model to meet the evolving demands of customers post-COVID. CPA and fnancial frms producing quality of earnings reports will have an especially difcult task assessing the going concern of a business, of normalizing performance in 2020 and preparing projections on run rate sales and EBITDA. "Depending on the concept, we anticipate increasing capital requirements and facility upgrades as brands and operators focus on refning their business model to meet the evolving demands of customers post-COVID."
Weak heating events are frequent and ubiquitous in solar corona. They derive their energy from the local magnetic field and form a major source of local heating, signatures of which are seen in EUV ...and X-ray bands. Their radio emission arise from various plasma instabilities that lead to coherent radiation, making even a weak flare appear very bright. The radio observations hence probe non-equilibrium dynamics providing complementary information on plasma evolution. However, a robust study of radio emission from a weak event among many simultaneous events, requires high dynamic range imaging at sub-second andsub-MHz resolutions owing to their high spectro-temporal variability. Such observations were not possible until recently.This is among the first spatially resolved studies of an active region loop hosting a transient brightening (ARTB) and dynamically linked to a metrewave type-I noise storm. It uses imaging observations at metrewave, EUV and X-ray bands, along with magnetogram data. We believe this is the first spectroscopic radio imaging study of a type-I source, the data for which was obtained using the Murchison Widefield Array. We report the discovery of 30 s quasi-periodic oscillations (QPOs) in the radio light curve, riding on a coherent baseline flux. The strength of the QPOs and the baseline flux enhanced during a mircoflare associated with the ARTB. Our observations suggest a scenario where magnetic stress builds up over an Alfv\'{e}n timescale (30s) across the typical magnetic field braiding scale and then dissipates via a cascade of weak reconnection events.
Rapid and stepwise changes of the magnetic field are often observed during flares but cannot be explained by models yet. Using a 45 min sequence of SDO/HMI 135 s fast-cadence vector magnetograms of ...the X1 flare on 2014-03-29 we construct, at each timestep, nonlinear force-free models for the coronal magnetic field. Observed flare-related changes in the line-of-sight magnetic field \(B_{\rm LOS}\) at the photosphere and chromosphere are compared with changes in the magnetic fields in the models. We find a moderate agreement at the photospheric layer (the basis for the models), but no agreement at chromospheric layers. The observed changes at the photosphere and chromosphere are surprisingly different, and are unlikely to be reproduced by a force-free model. The observed changes are likely to require a change in the magnitude of the field, not just in its direction.
We present coronal density profiles derived from low-frequency (80-240 MHz) imaging of three type III solar radio bursts observed at the limb by the Murchison Widefield Array (MWA). Each event is ...associated with a white light streamer at larger heights and is plausibly associated with thin extreme ultraviolet rays at lower heights. Assuming harmonic plasma emission, we find average electron densities of 1.8 x10^8 cm^-3 down to 0.20 x10^8 cm^-3 at heights of 1.3 to 1.9 solar radii. These values represent roughly 2.4-5.4x enhancements over canonical background levels and are comparable to the highest streamer densities obtained from data at other wavelengths. Assuming fundamental emission instead would increase the densities by a factor of 4. High densities inferred from type III source heights can be explained by assuming that the exciting electron beams travel along overdense fibers or by radio propagation effects that may cause a source to appear at a larger height than the true emission site. We review the arguments for both scenarios in light of recent results. We compare the extent of the quiescent corona to model predictions to estimate the impact of propagation effects, which we conclude can only partially explain the apparent density enhancements. Finally, we use the time- and frequency-varying source positions to estimate electron beam speeds of between 0.24 and 0.60 c.
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1. D-1 receptors are now recognised to play a critical psychopharmacological role in the regulation of unconditioned motor and numerous other aspects of behaviour.
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2. There appears to exist a ...broad family of ‘D-1-like’ receptors in terms both of differential coupling to distinct messenger/transduction mechanisms and of gene cloning, whose behavioural roles remain to be clarified.
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3. The adenylyl cyclase-inhibiting benzazepine SK&F 83959 induces behavioural responses in rats that are similar to those induced by the full efficacy cyclase-stimulating isochroman A 68930 but not to those induced by its high efficacy partial agonist benzazepine congener R-6-Br-APB; these data indicate roles for individual ‘D-1-like’ receptors in mediating distinct elements of dopaminergic behaviour.
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4. The putative D-1 autoreceptor agonist B-HT 920 and the putative D-3 agonist 7-OH-DPAT demonstrate different behavioural profiles when given both alone and in combination with the selective ‘D-1-like’ antagonist BW 737C; D-3 receptors may participate in cooperative/synergistic but not in oppositional ‘D-1-like’: ‘D-2-like’ interactions.
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5. Such interactions apparent at the level of behaviour are complemented by evidence for similar interactions at numerous alternative levels of function, though these may differ between rodent and primate species.
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6. A broader range of more selective agonists and antagonists, able to distinguish between individual members of the ‘D-1-like’ and of the ‘D-2-like’ receptor families are needed to clarify these issues.
Here we describe for the first time a cell-based scintillation proximity assay using membrane soluble scintillants (MSS). MSS have a scintillant `head' group (2,5-diphenyloxazole) attached to a ...lipophilic `tail.' MSS do not scintillate in an aqueous environment in the presence of a radioactive source: however, in a non-aqueous environment, such as a lipid bilayer (e.g., liposome or cell membrane), scintillation does occur. MSS can be incorporated into liposomes. When these MSS-containing liposomes are fused with the plasma membranes of cells in culture the MSS are incorporated into the cell membrane. Radiolabelled molecules in close proximity to the cell membrane will then elicit a scintillation signal. This system has been used to successfully monitor
14Cmethionine uptake in HeLa cells and may be used in radiochemical and radioligand binding assays either in vivo or on microsomal preparations obtained from tissues. This new scintillation proximity technology could be readily adapted for high-throughput screening.
We present spectropolarimetric imaging observations of the solar corona at low frequencies (80 - 240 MHz) using the Murchison Widefield Array (MWA). These images are the first of their kind, and we ...introduce an algorithm to mitigate an instrumental artefact by which the total intensity signal contaminates the polarimetric images due to calibration errors. We then survey the range of circular polarization (Stokes V) features detected in over 100 observing runs near solar maximum during quiescent periods. First, we detect around 700 compact polarized sources across our dataset with polarization fractions ranging from less than 0.5% to nearly 100%. These sources exhibit a positive correlation between polarization fraction and total intensity, and we interpret them as a continuum of plasma emission noise storm (Type I burst) continua sources associated with active regions. Second, we report a characteristic "bullseye" structure observed for many low-latitude coronal holes in which a central polarized component is surrounded by a ring of the opposite sense. The central component does not match the sign expected from thermal bremsstrahlung emission, and we speculate that propagation effects or an alternative emission mechanism may be responsible. Third, we show that the large-scale polarimetric structure at our lowest frequencies is reasonably well-correlated with the line-of-sight (LOS) magnetic field component inferred from a global potential field source surface (PFSS) model. The boundaries between opposite circular polarization signs are generally aligned with polarity inversion lines in the model at a height roughly corresponding to that of the radio limb. This is not true at our highest frequencies, however, where the LOS magnetic field direction and polarization sign are often not straightforwardly correlated.
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