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zadetkov: 58
1.
  • The role of mucus on drug t... The role of mucus on drug transport and its potential to affect therapeutic outcomes
    Murgia, Xabier; Loretz, Brigitta; Hartwig, Olga ... Advanced drug delivery reviews, 01/2018, Letnik: 124
    Journal Article
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    Odprti dostop

    A layer of mucus covers the surface of all wet epithelia throughout the human body. Mucus is a hydrogel mainly composed of water, mucins (glycoproteins), DNA, proteins, lipids, and cell debris. This ...
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2.
  • Aerosol drug delivery to sp... Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned
    Bianco, Federico; Salomone, Fabrizio; Milesi, Ilaria ... Respiratory research, 02/2021, Letnik: 22, Številka: 1
    Journal Article
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    Delivery of medications to preterm neonates receiving non-invasive ventilation (NIV) represents one of the most challenging scenarios for aerosol medicine. This challenge is highlighted by the ...
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3.
  • Surfactant lung delivery wi... Surfactant lung delivery with LISA and InSurE in adult rabbits with respiratory distress
    Ricci, Francesca; Bresesti, Ilia; LaVerde, Paola Azzurra Maria ... Pediatric research, 09/2021, Letnik: 90, Številka: 3
    Journal Article
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    In preterm infants, InSurE (Intubation-Surfactant-Extubation) and LISA (less invasive surfactant administration) techniques allow for exogenous surfactant administration while reducing lung injury ...
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4.
  • Surfactant-Free Glibenclami... Surfactant-Free Glibenclamide Nanoparticles: Formulation, Characterization and Evaluation of Interactions with Biological Barriers
    Arrua, Eva C.; Hartwig, Olga; Ho, Duy-Khiet ... Pharmaceutical research, 06/2021, Letnik: 38, Številka: 6
    Journal Article
    Recenzirano

    Purpose The aim of this work was to formulate and characterize surfactant-free glibenclamide nanoparticles using Eudragit RLPO and polyethylene glycol as sole stabilizer. Methods Glibenclamide ...
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5.
  • Micro-rheological propertie... Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection
    Murgia, Xabier; Kany, Andreas M; Herr, Christian ... Scientific reports, 10/2020, Letnik: 10, Številka: 1
    Journal Article
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    Lung infections caused by Pseudomonas aeruginosa pose a serious threat to patients suffering from, among others, cystic fibrosis, chronic obstructive pulmonary disease, or bronchiectasis, often ...
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6.
  • Differential Performance an... Differential Performance and Lung Deposition of Levofloxacin with Different Nebulisers Used in Cystic Fibrosis
    Schwarz, Carsten; Procaccianti, Claudio; Costa, Laura ... International journal of molecular sciences, 08/2022, Letnik: 23, Številka: 17
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    We compared the performance and levofloxacin (Quinsair) lung deposition of three nebulisers commonly used in CF (I-Neb Advance, eFlow rapid, and LC Plus) with the approved nebuliser Zirela. The ...
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7.
  • Physiological, Biochemical,... Physiological, Biochemical, and Biophysical Characterization of the Lung-Lavaged Spontaneously-Breathing Rabbit as a Model for Respiratory Distress Syndrome
    Ricci, Francesca; Catozzi, Chiara; Murgia, Xabier ... PloS one, 01/2017, Letnik: 12, Številka: 1
    Journal Article
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    Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in spontaneously-breathing premature infants with respiratory distress syndrome ...
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8.
  • Time-resolved transcriptomi... Time-resolved transcriptomic profiling of the developing rabbit's lungs: impact of premature birth and implications for modelling bronchopulmonary dysplasia
    Storti, Matteo; Faietti, Maria Laura; Murgia, Xabier ... Respiratory research, 03/2023, Letnik: 24, Številka: 1
    Journal Article
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    Premature birth, perinatal inflammation, and life-saving therapies such as postnatal oxygen and mechanical ventilation are strongly associated with the development of bronchopulmonary dysplasia ...
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9.
  • Deposition of Inhaled Levof... Deposition of Inhaled Levofloxacin in Cystic Fibrosis Lungs Assessed by Functional Respiratory Imaging
    Schwarz, Carsten; Procaccianti, Claudio; Mignot, Benjamin ... Pharmaceutics, 12/2021, Letnik: 13, Številka: 12
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    Pulmonary infections caused by (PA) represent the leading cause of pulmonary morbidity in adults with cystic fibrosis (CF). In addition to tobramycin, colistin, and aztreonam, levofloxacin has been ...
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10.
  • A New PqsR Inverse Agonist ... A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms
    Schütz, Christian; Ho, Duy‐Khiet; Hamed, Mostafa Mohamed ... Advanced science, 06/2021, Letnik: 8, Številka: 12
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    Pseudomonas aeruginosa (PA) infections can be notoriously difficult to treat and are often accompanied by the development of antimicrobial resistance (AMR). Quorum sensing inhibitors (QSI) acting on ...
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zadetkov: 58

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