In a gene mapping study on 217 newborn babies in Taiwan with alpha- and zeta-globin probes, we have observed 4 cases (1.84%) of alpha-thalassemia-2 heterozygotes (zeta zeta-alpha/zeta zeta alpha ...alpha) without increased levels of hemoglobin (Hb) Bart's in the cord blood. Eleven subjects (5.07%) were found to have the South East Asian alpha-thalassemia-1 haplotype (zeta zeta--SEA/zeta zeta alpha alpha) with increased Hb Bart's levels ranging from 2.2 to 9%. One case, with Hb Bart's level of 14% in the cord blood, was found to have the genotype of zeta zeta--SEA/zeta zeta alpha alpha T (0.46%). Four heterozygotes (1.84%) were found with the triple alpha gene anti-rightward arrangement (zeta zeta alpha alpha alpha 3.7/zeta zeta alpha alpha). Twenty-one heterozygotes (9.68%) were found to have the triple zeta-globin gene arrangement (zeta zeta zeta alpha alpha/zeta zeta alpha alpha). A new triple zeta-globin gene variant with a BamHI polymorphism was also observed in this study.
In the present study, we have demonstrated the synthesis of large-area vertically aligned silicon nanowire (SiNW) arrays in an aqueous solution containing AgNCh and HF on p-type (001) Si substrate by ...self-selective electroless etching process. The fabrication process was rather simple and rapid compared to the well-known Vapor-Liquid-Solid (VLS) growth via chemical-vapor deposition (CVD) and other highvacuum techniques. In this work, the temperature of electrolyte and etching duration were varied in order to achieve different stages of nanowire formation. Diameters of the SiNWs obtained varied from 50 nm to 200 nm and their lengths ranged from several to approximately a few tens of μm, depending on the reaction time and the electrolyte conditions used. Te-Si and Bi 2 Te 3 -Si core-shell structures were subsequently obtained via galvanic displacement of SiNWs in acidic HF electrolytes containing Bi 3+ and Bi 3+ /HTeO 2 + ions respectively.
A case of 17-year-old girl with primary myxoma of the cranium is presented. The lesion ballooned the inner and outer tables of the cranium and expanded intracranially, causing neurologic deficits. ...The lesion is rare and its radiographic, including CT, features are described.
Computer-Based Classification of Eye Diseases Acharya, U.R.; Kannathal, N.; Ng, E.Y.K. ...
2006 International Conference of the IEEE Engineering in Medicine and Biology Society,
2006, Letnik:
2006
Conference Proceeding, Journal Article
Eye disorders among the elderly are a major health problem. With advancing age, the normal function of eye tissues decreases and there is an increased incidence of ocular pathology. The most common ...causes of age related eye disorder and visual impairment in the elderly are cataracts, iridocyclitis and corneal haze. Iridocyclitis is an inflammation of the iris (the colored part of the eye), while corneal haze is a complication of refractive surgery characterized by the cloudiness of the normally clear cornea. Computer-based intelligent system for classification of these eye diseases is very useful in diagnostics and disease management. This paper presents a comparison of three classification strategies to classify four kinds of eye data sets (three different kinds of eye diseases and a normal class). Our protocol uses three different kinds of classifiers: artificial neural network, fuzzy classifier and neuro-fuzzy classifier. Features are extracted from these raw images which are then fed to these classifiers. These classifiers are run on a database of 135 subjects using the cross-validation strategy. We demonstrate a sensitivity of more than 85% for these classifiers with the specificity of 100% and results are very promising
A retrospective clinical follow-up study of 96 inguinal hernia repairs by a general surgeon over a period of five and a half years using the same method of repair is discussed here with results of ...follow-up, post-operative complications and recurrence rates. The period of follow-up ranges from one month to five and a half years and no case of inguinal recurrence has so far been reported. One femoral recurrence was reported and its possible link to the Shouldice methodology is discussed. The average length of hospital stay has decreased over the five and a half year period.
A self contained thermosyphon-cooled flexible bellow liquid heat sink was developed for cooling electronic circuit boards. The prototype system combines the benefits of both flexible bellows and ...thermosyphon technology. A finned flat-plate thermosyphon was designed and tested for natural convection application under various heat source temperatures. Extensive measurements were made on the combined heat sink system comprising the flat-plate thermosyphon and the flexible bellows. Experimental results showed that the dissipation capacity of the prototype liquid heat sink is about 0.006 W/cm/sup 2/K, which is about six times larger than that using normal convection cooling by the ambient surrounding. The system can maintain the temperature of the heat sources at about 20 K lower that without the application of such a system.
Molecular analysis of hemoglobin H disease in Taiwan Lee, H H; Cheung, W F; Chang, J G ...
Proceedings of the National Science Council, Republic of China, Part B, Life sciences
12, Številka:
1
Journal Article
Recenzirano
The molecular basis of seven Chinese patients in Taiwan with hemoglobin H disease was investigated and was found to be heterogeneous in the mutation type. They were alpha-thalassemia-1 mutation ...combined with hemoglobin Constant Spring, an undetermined nondeletion form of alpha-thalassemia and a deletion form of alpha-thalassemia-2 mutations. The alpha-thalassemia-1 mutation was shown to be the --SEA type I haplotype.
We have analysed seven polymorphic restriction sites of the human beta-globin gene cluster of six members of a Chinese family with a beta +-thalassemic sibling. The seven polymorphic sites analysed ...are the HincII site at the 5'-end of the epsilon-globin gene, the HindIII sites in the two gamma-globin genes, two HincII sites within and at the 3'-end of the psi beta 1 pseudogene, the AvaII site in the beta-globin gene and the BamHI site located at the 3' side of the beta-globin gene. The beta thal chromosome has been identified to have a haplotype of +---++ with respect to these seven polymorphic sites. This is also the most predominant haplotype associated with beta +-thalassemia in Mediterranean and Chinese populations (Chen et al., 1984; Orkin et al., 1982). Of the seven sites analysed in this family, four will be useful in prenatal diagnosis of beta-thalassemia in subsequent pregnancies in the family.
