We present Hubble Space Telescope near-infrared transmission spectroscopy of the transiting hot-Jupiter HAT-P-1b. We observed one transit with Wide Field Camera 3 using the G141 low-resolution grism ...to cover the wavelength range 1.087-1.678 μm. These time series observations were taken with the newly available spatial-scan mode that increases the duty cycle by nearly a factor of 2, thus improving the resulting photometric precision of the data. We measure a planet-to-star radius ratio of R
p/R
* = 0.117 09 ± 0.000 38 in the white light curve with the centre of transit occurring at 245 6114.345 ± 0.000 133 (JD). We achieve S/N levels per exposure of 1840 (0.061 per cent) at a resolution of Δλ = 19.2 nm (R ∼ 70) in the 1.1173-1.6549 μm spectral region, providing the precision necessary to probe the transmission spectrum of the planet at close to the resolution limit of the instrument. We compute the transmission spectrum using both single target and differential photometry with similar results. The resultant transmission spectrum shows a significant absorption above the 5σ level matching the 1.4 μm water absorption band. In solar composition models, the water absorption is sensitive to the ∼1 m bar pressure levels at the terminator. The detected absorption agrees with that predicted by a 1000 K isothermal model, as well as with that predicted by a planetary-averaged temperature model.
We present Hubble Space Telescope optical and near-IR transmission spectra of the transiting hot-Jupiter WASP-31b. The spectrum covers 0.3-1.7 mu m at a resolution R similar to 70, which we combine ...with Spitzer photometry to cover the full-optical to IR. The spectrum is dominated by a cloud deck with a flat transmission spectrum which is apparent at wavelengths > 0.52 mu m. The cloud deck is present at high altitudes and low pressures, as it covers the majority of the expected optical Na line and near-IR H2O features. While Na I absorption is not clearly identified, the resulting spectrum does show a very strong potassium feature detected at the 4.2- sigma confidence level. Broadened alkali wings are not detected, indicating pressures below similar to 10 mbar. The lack of Na and strong K is the first indication of a sub-solar Na/K abundance ratio in a planetary atmosphere (lnNa/K = -3.3 plus or minus 2.8), which could potentially be explained by Na condensation on the planet's night side, or primordial abundance variations. A strong Rayleigh scattering signature is detected at short wavelengths, with a 4- sigma significant slope. Two distinct aerosol size populations can explain the spectra, with a smaller sub-micron size grain population reaching high altitudes producing a blue Rayleigh scattering signature on top of a larger, lower lying population responsible for the flat cloud deck at longer wavelengths. We estimate that the atmospheric circulation is sufficiently strong to mix micron size particles upwards to the required 1-10 mbar pressures, necessary to explain the cloud deck. These results further confirm the importance of clouds in hot Jupiters, which can potentially dominate the overall spectra and may alter the abundances of key gaseous species.
We present Hubble Space Telescope (HST) optical transmission spectra of the transiting hot-Jupiter WASP-12b, taken with the Space Telescope Imaging Spectrograph instrument. The resulting spectra ...cover the range 2900-10 300 A which we combined with archival Wide Field Camera 3 spectra and Spitzer photometry to cover the full optical to infrared wavelength regions. With high spatial resolution, we are able to resolve WASP-12A's stellar companion in both our images and spectra, revealing that the companion is in fact a close binary M0V pair, with the three stars forming a triple-star configuration. We derive refined physical parameters of the WASP-12 system, including the orbital ephemeris, finding the exoplanet's density is ~20 per cent lower than previously estimated. From the transmission spectra, we are able to decisively rule out prominent absorption by TiO in the exoplanet's atmosphere, as there are no signs of the molecule's characteristic broad features nor individual bandheads. Strong pressure-broadened Na and K absorption signatures are also excluded, as are significant metal-hydride features. We compare our combined broad-band spectrum to a wide variety of existing aerosol-free atmospheric models, though none are satisfactory fits. However, we do find that the full transmission spectrum can be described by models which include significant opacity from aerosols: including Rayleigh scattering, Mie scattering, tholin haze and settling dust profiles. The transmission spectrum follows an effective extinction cross-section with a power law of index α, with the slope of the transmission spectrum constraining the quantity αT = -3528 ± 660 K, where T is the atmospheric temperature. Rayleigh scattering (α = -4) is among the best-fitting models, though requires low terminator temperatures near 900 K. Sub-micron size aerosol particles can provide equally good fits to the entire transmission spectrum for a wide range of temperatures, and we explore corundum as a plausible dust aerosol. The presence of atmospheric aerosols also helps to explain the modestly bright albedo implied by Spitzer observations, as well as the near blackbody nature of the emission spectrum. Ti-bearing condensates on the cooler night-side is the most natural explanation for the overall lack of TiO signatures in WASP-12b, indicating the day/night cold trap is an important effect for very hot Jupiters. These findings indicate that aerosols can play a significant atmospheric role for the entire wide range of hot-Jupiter atmospheres, potentially affecting their overall spectrum and energy balance. PUBLICATION ABSTRACT
We present an optical to near-infrared transmission spectrum of the hot Jupiter HAT-P-1b, based on Hubble Space Telescope observations, covering the spectral regime from 0.29 to 1.027 μm with Space ...Telescope Imaging Spectrograph (STIS), which is coupled with a recent Wide Field Camera 3 (WFC3) transit (1.087 to 1.687 μm). We derive refined physical parameters of the HAT-P-1 system, including an improved orbital ephemeris. The transmission spectrum shows a strong absorption signature shortward of 0.55 μm, with a strong blueward slope into the near-ultraviolet. We detect atmospheric sodium absorption at a 3.3σ significance level, but find no evidence for the potassium feature. The red data imply a marginally flat spectrum with a tentative absorption enhancement at wavelength longer than ∼ 0.85 μm. The STIS and WFC3 spectra differ significantly in absolute radius level (4.3 ± 1.6 pressure scaleheights), implying strong optical absorption in the atmosphere of HAT-P-1b. The optical to near-infrared difference cannot be explained by stellar activity, as simultaneous stellar activity monitoring of the G0V HAT-P-1b host star and its identical companion show no significant activity that could explain the result. We compare the complete STIS and WFC3 transmission spectrum with theoretical atmospheric models which include haze, sodium and an extra optical absorber. We find that both an optical absorber and a supersolar sodium to water abundance ratio might be a scenario explaining the HAT-P-1b observations. Our results suggest that strong optical absorbers may be a dominant atmospheric feature in some hot Jupiter exoplanets.
The contamination of feeds and foods with mycotoxins is a global ecological and public health issue. The effects of fungi growing on feeds and of mycotoxins produced by them are outlined with the ...fact that even minimum concentrations, especially in cases of potentiated synergism and continuous exposure, may cause substantial harm to health manifested with immunosuppression, reproductive disorders in farm animals and hence, reduced productive performance and great economic losses. By affecting numerous economic sectors and the food industry in particular, mycotoxins pose a huge threat to animal and human health. The Food and Agriculture Organization (FAO) reports that 25% of global food crops used as primary feed ingredients in animal and human nutrition are affected by mycotoxins and contaminated as early as during the stages of plant growth, harvesting, transportation or storage.
The most important mycotoxins, subject to extensive research and of enormous economic relevance in modern livestock husbandry, pig farming in particular, are deoxynivalenol (DON), zearalenone (ZEA), T-2 toxin (T-2), fumonisin B1 (FB1), ochratoxin A (OTA) and aflatoxin B1 (AFB1). The present review describes zearalenone (ZEA) as one of the main pig feed contaminants, its prevalence,
toxicokinetics, toxicodynamics and clinical signs.
Gastrointestinal helminth parasites can be transferred during conservation translocations and impact their outcome. The current study applied non-invasive coprological sampling to investigate the ...helminth infection rates and dynamics in translocated and resident European ground squirrels, during and after a population reinforcement. The FLOTAC method was calibrated and applied for the first time for the target species. In the studied coprological samples, helminth eggs belonging to Acanthocephala and Nematoda were found; the latter were morphologically identified as belonging to the families Capillariidae (Enoplida) and Trichostrongylidae (Strongylida) and superfamily Spiruroidea (Spirurida). The overall helminth prevalence and their diversity were higher in the donor colony compared to the resident one before the reinforcement. Pronounced seasonal dynamics in the parasite prevalence and diversity were observed, and their values were considerably lower in spring than in summer in both translocated and resident hosts. A year after the start of the translocation, the helminth prevalence and number of species detected in the reinforced colony had increased significantly. This is in accordance with epidemiological models and other empirical studies that predict a positive relationship between the population density of a host and the prevalence and species richness of parasites.
Abstract
For solar system objects, ultraviolet spectroscopy has been critical in identifying sources of stratospheric heating and measuring the abundances of a variety of hydrocarbon and ...sulfur-bearing species, produced via photochemical mechanisms, as well as oxygen and ozone. To date, fewer than 20 exoplanets have been probed in this critical wavelength range (0.2–0.4
μ
m). Here we use data from Hubble’s newly implemented WFC3 UVIS G280 grism to probe the atmosphere of the hot Jupiter HAT-P-41b in the ultraviolet through optical in combination with observations at infrared wavelengths. We analyze and interpret HAT-P-41b’s 0.2–5.0
μ
m transmission spectrum using a broad range of methodologies including multiple treatments of data systematics as well as comparisons with atmospheric forward, cloud microphysical, and multiple atmospheric retrieval models. Although some analysis and interpretation methods favor the presence of clouds or potentially a combination of Na, VO, AlO, and CrH to explain the ultraviolet through optical portions of HAT-P-41b’s transmission spectrum, we find that the presence of a significant H
−
opacity provides the most robust explanation. We obtain a constraint for the abundance of H
−
,
, in HAT-P-41b’s atmosphere, which is several orders of magnitude larger than predictions from equilibrium chemistry for a ∼1700–1950 K hot Jupiter. We show that a combination of photochemical and collisional processes on hot hydrogen-dominated exoplanets can readily supply the necessary amount of H
−
and suggest that such processes are at work in HAT-P-41b and the atmospheres of many other hot Jupiters.
We present 17 high-precision light curves of five transits of the planet Qatar-2 b, obtained from four defocused 2 m-class telescopes. Three of the transits were observed simultaneously in the Sloan ...g
′
r
′
i
′
z
′ passbands using the seven-beam Gamma Ray Burst Optical and Near-Infrared Detector imager on the MPG/ESO 2.2-m telescope. A fourth was observed simultaneously in Gunn grz using the Centro Astronómico Hispano Alemán 2.2-m telescope with Bonn University Simultaneous Camera, and in r using the Cassini 1.52-m telescope. Every light curve shows small anomalies due to the passage of the planetary shadow over a cool spot on the surface of the host star. We fit the light curves with the prism+gemc model to obtain the photometric parameters of the system and the position, size and contrast of each spot. We use these photometric parameters and published spectroscopic measurements to obtain the physical properties of the system to high precision, finding a larger radius and lower density for both star and planet than previously thought. By tracking the change in position of one star-spot between two transit observations, we measure the orbital obliquity of Qatar-2 b to be λ = 4
$_{.}^{\circ}$
3 ± 4
$_{.}^{\circ}$
5, strongly indicating an alignment of the stellar spin with the orbit of the planet. We calculate the rotation period and velocity of the cool host star to be 11.5 ± 0.2 d and 3.28 ± 0.04 km s−1 at a colatitude of 74°. We assemble the planet's transmission spectrum over the 386–976 nm wavelength range and search for variations of the measured radius of Qatar-2 b as a function of wavelength. Our analysis highlights a possible H2/He Rayleigh scattering in the blue.
Osteoarthritis (OA) drug development is hampered by a number of challenges. One of the main challenges is the apparent discordance between pain and structure, which has had a significant impact on ...drug development programs and has led to hesitance among stakeholders. Since 2017, the Clinical Trials Symposium (CTS) has been hosted under the Osteoarthritis Research Society International (OARSI) leadership. OARSI and the CTS steering committee yearly invite and encourage discussions on selected special subject matter between regulators, drug developers, clinicians, clinical researchers, biomarker specialists, and basic scientists to progress drug development in the OA field.
The main topic for the 2022 OARSI CTS was to elucidate the many facets of pain in OA and to enable a discussion between regulators (Food and Drug Administration (FDA) and the European Medicines Agency (EMA)) and drug developers to clarify outcomes and study designs for OA drug development.
Signs or symptoms indicative of nociceptive pain occur in 50–70% of OA patients, neuropathic-like pain in 15–30% of patients, and nociplastic pain in 15–50% of patients. Weight-bearing knee pain is associated with bone marrow lesions and effusions. There are currently no simple objective functional tests whose improvements correlate with patient perceptions.
The CTS participants, in collaboration with the FDA and EMA, raised several suggestions that they consider key to future clinical trials in OA including the need for more precise differentiation of pain symptoms and mechanisms, and methods to reduce placebo responses in OA trials.
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