Transcriptomic analysis was carried out for the top 70 DA associated SNPs using available transcription factor (TF) datasets from relevant lung-derived tissues and cell lines, including ChIP- seq ...datasets for TFs, regulatory histone marks, and DNase-seq (open chromatin).
...ferritin levels were not downregulated and transferrin levels were not upregulated in sera samples from the population we studied. ...in the population studied, serum ferritin and transferrin ...values did not differ among TDI-OA, TDI-exposed workers without occupational asthma, or healthy control patients, and therefore cannot be used as serologic markers for identifying TDI-OA.
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