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zadetkov: 13
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  • A combined adjuvant approac... A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates
    Phung, Ivy; Rodrigues, Kristen A; Marina-Zárate, Ester ... Nature communications, 11/2023, Letnik: 14, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Adjuvants and antigen delivery kinetics can profoundly influence B cell responses and should be critically considered in rational vaccine design, particularly for difficult neutralizing antibody ...
Celotno besedilo
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  • An oncogenic mutant of RHEB... An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation
    Heard, Jeffrey J; Phung, Ivy; Potes, Mark I ... BMC cancer, 01/2018, Letnik: 18, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    RHEB is a unique member of the RAS superfamily of small GTPases expressed in all tissues and conserved from yeast to humans. Early studies on RHEB indicated a possible RHEB-RAF interaction, but this ...
Celotno besedilo

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  • Long-primed germinal centre... Long-primed germinal centres with enduring affinity maturation and clonal migration
    Lee, Jeong Hyun; Sutton, Henry J; Cottrell, Christopher A ... Nature, 09/2022, Letnik: 609, Številka: 7929
    Journal Article
    Recenzirano
    Odprti dostop

    Germinal centres are the engines of antibody evolution. Here, using human immunodeficiency virus (HIV) Env protein immunogen priming in rhesus monkeys followed by a long period without further ...
Celotno besedilo
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  • Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates
    Steichen, Jon M; Phung, Ivy; Salcedo, Eugenia ... Science (American Association for the Advancement of Science), 2024-May-17, Letnik: 384, Številka: 6697
    Journal Article
    Recenzirano

    Germline-targeting immunogens hold promise for initiating the induction of broadly neutralizing antibodies (bnAbs) to HIV and other pathogens. However, antibody-antigen recognition is typically ...
Preverite dostopnost
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  • A particulate saponin/TLR a... A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
    Silva, Murillo; Kato, Yu; Melo, Mariane B ... Science immunology, 12/2021, Letnik: 6, Številka: 66
    Journal Article
    Recenzirano
    Odprti dostop

    Saponins are potent and safe vaccine adjuvants, but their mechanisms of action remain incompletely understood. Here, we explored the properties of several saponin formulations, including ...
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zadetkov: 13

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