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zadetkov: 35
1.
  • Efficient protein productio... Efficient protein production inspired by how spiders make silk
    Kronqvist, Nina; Sarr, Médoune; Lindqvist, Anton ... Nature communications, 05/2017, Letnik: 8, Številka: 1
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    Membrane proteins are targets of most available pharmaceuticals, but they are difficult to produce recombinantly, like many other aggregation-prone proteins. Spiders can produce silk proteins at huge ...
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2.
  • Quenching of tryptophan flu... Quenching of tryptophan fluorescence in a highly scattering solution: Insights on protein localization in a lung surfactant formulation
    Ronda, Luca; Pioselli, Barbara; Catinella, Silvia ... PloS one, 08/2018, Letnik: 13, Številka: 8
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    CHF5633 (Chiesi Farmaceutici, Italy) is a synthetic surfactant developed for respiratory distress syndrome replacement therapy in pre-term newborn infants. CHF5633 contains two phospholipids ...
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3.
  • In vitro characterization a... In vitro characterization and in vivo comparison of the pulmonary outcomes of Poractant alfa and Calsurf in ventilated preterm rabbits
    Guo, Xiaojing; Luo, Siwei; Amidani, Davide ... PloS one, 03/2020, Letnik: 15, Številka: 3
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    Poractant alfa and Calsurf are two natural surfactants widely used in China for the treatment of neonatal respiratory distress syndrome, which are extracted from porcine and calf lungs, respectively. ...
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4.
  • Time-resolved transcriptomi... Time-resolved transcriptomic profiling of the developing rabbit's lungs: impact of premature birth and implications for modelling bronchopulmonary dysplasia
    Storti, Matteo; Faietti, Maria Laura; Murgia, Xabier ... Respiratory research, 03/2023, Letnik: 24, Številka: 1
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    Premature birth, perinatal inflammation, and life-saving therapies such as postnatal oxygen and mechanical ventilation are strongly associated with the development of bronchopulmonary dysplasia ...
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5.
  • Physiological, Biochemical,... Physiological, Biochemical, and Biophysical Characterization of the Lung-Lavaged Spontaneously-Breathing Rabbit as a Model for Respiratory Distress Syndrome
    Ricci, Francesca; Catozzi, Chiara; Murgia, Xabier ... PloS one, 01/2017, Letnik: 12, Številka: 1
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    Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in spontaneously-breathing premature infants with respiratory distress syndrome ...
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6.
  • Beyond the Interface: Impro... Beyond the Interface: Improved Pulmonary Surfactant-Assisted Drug Delivery through Surface-Associated Structures
    García-Mouton, Cristina; Echaide, Mercedes; Serrano, Luis A ... Pharmaceutics, 01/2023, Letnik: 15, Številka: 1
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    Pulmonary surfactant (PS) has been proposed as an efficient drug delivery vehicle for inhaled therapies. Its ability to adsorb and spread interfacially and transport different drugs associated with ...
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7.
  • Mass spectrometry imaging a... Mass spectrometry imaging as a tool for evaluating the pulmonary distribution of exogenous surfactant in premature lambs
    Zecchi, Riccardo; Franceschi, Pietro; Tigli, Laura ... Respiratory research, 08/2019, Letnik: 20, Številka: 1
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    The amount of surfactant deposited in the lungs and its overall pulmonary distribution determine the therapeutic outcome of surfactant replacement therapy. Most of the currently available methods to ...
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8.
  • Daily Intraperitoneal Admin... Daily Intraperitoneal Administration of Rosiglitazone Does Not Improve Lung Function or Alveolarization in Preterm Rabbits Exposed to Hyperoxia
    Aquila, Giorgio; Regin, Yannick; Murgia, Xabier ... Pharmaceutics, 07/2022, Letnik: 14, Številka: 7
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    Thiazolidinediones (TZDs) are potent PPARγ agonists that have been shown to attenuate alveolar simplification after prolonged hyperoxia in term rodent models of bronchopulmonary dysplasia. However, ...
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9.
  • Surfactant-Assisted Distal ... Surfactant-Assisted Distal Pulmonary Distribution of Budesonide Revealed by Mass Spectrometry Imaging
    Zecchi, Riccardo; Franceschi, Pietro; Tigli, Laura ... Pharmaceutics, 06/2021, Letnik: 13, Številka: 6
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    Direct lung administration of budesonide in combination with surfactant reduces the incidence of bronchopulmonary dysplasia. Although the therapy is currently undergoing clinical development, the ...
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10.
  • Absolute quantification of ... Absolute quantification of superoxide dismutase (SOD) using species-specific isotope dilution analysis
    Deitrich, Christian L; Braukmann, Sandra; Raab, Andrea ... Analytical and bioanalytical chemistry, 08/2010, Letnik: 397, Številka: 8
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    Here we report for the first time the use of species-specific isotope dilution mass spectrometry for the absolute quantification of a metalloprotein using non-denaturing gel electrophoresis laser ...
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zadetkov: 35

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