Abstract
We used high-precision radial velocity measurements of FGKM stars to determine the occurrence of giant planets as a function of orbital separation spanning 0.03–30 au. Giant planets are more ...prevalent at orbital distances of 1–10 au compared to orbits interior or exterior of this range. The increase in planet occurrence at ∼1 au by a factor of ∼4 is highly statistically significant. A fall-off in giant planet occurrence at larger orbital distances is favored over models with flat or increasing occurrence. We measure
14.1
−
1.8
+
2.0
giant planets per 100 stars with semimajor axes of 2–8 au and
8.9
−
2.4
+
3.0
giant planets per 100 stars in the range 8–32 au, a decrease in occurrence with increasing orbital separation that is significant at the ∼2
σ
level. We find that the occurrence rate of sub-Jovian planets (0.1–1 Jupiter masses) is also enhanced for 1–10 au orbits. This suggests that lower-mass planets may share the formation or migration mechanisms that drive the increased prevalence near the water–ice line for their Jovian counterparts. Our measurements of cold gas giant occurrence are consistent with the latest results from direct imaging surveys and gravitational lensing surveys despite different stellar samples. We corroborate previous findings that giant planet occurrence increases with stellar mass and metallicity.
Abstract
We present a high-precision radial velocity (RV) survey of 719 FGKM stars, which host 164 known exoplanets and 14 newly discovered or revised exoplanets and substellar companions. This ...catalog updated the orbital parameters of known exoplanets and long-period candidates, some of which have decades-longer observational baselines than they did upon initial detection. The newly discovered exoplanets range from warm sub-Neptunes and super-Earths to cold gas giants. We present the catalog sample selection criteria, as well as over 100,000 RV measurements, which come from the Keck-HIRES, APF-Levy, and Lick-Hamilton spectrographs. We introduce the new RV search pipeline
RVSearch
(
https://california-planet-search.github.io/rvsearch/
) that we used to generate our planet catalog, and we make it available to the public as an open-source Python package. This paper is the first study in a planned series that will measure exoplanet occurrence rates and compare exoplanet populations, including studies of giant planet occurrence beyond the water ice line, and eccentricity distributions to explore giant planet formation pathways. We have made public all radial velocities and associated data that we use in this catalog.
Background
The combination of chemotherapy with thoracic radiotherapy (TRT) compared with TRT alone has been shown to confer a survival advantage for good performance status patients with stage III ...non-small cell lung cancer. However, it is not known whether sequential or concurrent delivery of these therapies is the optimal combination strategy.
Methods
A total of 610 patients were randomly assigned to two concurrent regimens and one sequential chemotherapy and TRT regimen in a three-arm phase III trial. The sequential arm included cisplatin at 100 mg/m2 on days 1 and 29 and vinblastine at 5 mg/m2 per week for 5 weeks with 60 Gy TRT beginning on day 50. Arm 2 used the same chemotherapy regimen as arm 1 with 60 Gy TRT once daily beginning on day 1. Arm 3 used cisplatin at 50 mg/m2 on days 1, 8, 29, and 36 with oral etoposide at 50 mg twice daily for 10 weeks on days 1, 2, 5, and 6 with 69.6 Gy delivered as 1.2 Gy twice-daily fractions beginning on day 1. The primary endpoint was overall survival, and secondary endpoints included tumor response and time to tumor progression. Kaplan-Meier analyses were used to assess survival, and toxic effects were examined using the Wilcoxon rank sum test. All statistical tests were two-sided.
Results
Median survival times were 14.6, 17.0, and 15.6 months for arms 1-3, respectively. Five-year survival was statistically significantly higher for patients treated with the concurrent regimen with once-daily TRT compared with the sequential treatment (5-year survival: sequential, arm 1, 10% 20 patients, 95% confidence interval CI = 7% to 15%; concurrent, arm 2, 16% 31 patients, 95% CI = 11% to 22%, P = .046; concurrent, arm 3, 13% 22 patients, 95% CI = 9% to 18%). With a median follow-up time of 11 years, the rates of acute grade 3-5 nonhematologic toxic effects were higher with concurrent than sequential therapy, but late toxic effects were similar.
Conclusion
Concurrent delivery of cisplatin-based chemotherapy with TRT confers a long-term survival benefit compared with the sequential delivery of these therapies.
Abstract
It is widely assumed that long-wavelength infrared (IR) emission from cold dust (
T
∼ 20–40 K) is a reliable tracer of star formation even in the presence of a bright active galactic nucleus ...(AGN). Based on radiative transfer (RT) models of clumpy AGN tori, hot dust emission from the torus contributes negligibly to the galaxy spectral energy distribution (SED) at
λ
≳ 100
μ
m. However, these models do not include AGN heating of host-galaxy-scale diffuse dust, which may have far-IR (FIR) colors comparable to cold diffuse dust heated by stars. To quantify the contribution of AGN heating to host-galaxy-scale cold dust emission at
λ
≳ 100
μ
m, we perform dust RT calculations on a simulated galaxy merger both including and excluding the bright AGN that it hosts. By differencing the SEDs yielded by RT calculations with and without AGNs that are otherwise identical, we quantify the FIR cold dust emission arising solely from reprocessed AGN photons. In extreme cases, AGN-heated host-galaxy-scale dust can increase galaxy-integrated FIR flux densities by factors of 2–4; star formation rates calculated from the FIR luminosity assuming no AGN contribution can overestimate the true value by comparable factors. Because the FIR colors of such systems are similar to those of purely star-forming galaxies and redder than torus models, broadband SED decomposition may be insufficient for disentangling the contributions of stars and heavily dust-enshrouded AGNs in the most IR-luminous galaxies. We demonstrate how kiloparsec-scale resolved observations can be used to identify deeply dust-enshrouded AGNs with cool FIR colors when spectroscopic and/or X-ray detection methods are unavailable.
Abstract
We compare systems with single giant planets to systems with multiple giant planets using a catalog of planets from a high-precision radial velocity survey of FGKM stars. Our comparison ...focuses on orbital properties, planet masses, and host-star properties. We use hierarchical methods to model the orbital eccentricity distributions of giant singles and giant multiples, and find that the distributions are distinct. The multiple giant planets typically have moderate eccentricities and their eccentricity distribution extends to
e
= 0.47 (90th percentile), while the single giant planets have a pileup of nearly circular orbits and a long tail that extends to
e
= 0.77. We determine that the stellar hosts of multiple giants are distinctly more metal rich than the hosts of solitary giants, with respective mean metallicities of 0.228 ± 0.027 versus 0.129 ± 0.019 dex. We measure the distinct occurrence distributions of single and multiple giants with respect to orbital separation, and find that single gas giants have a ∼2.3
σ
significant hot Jupiter (
a
< 0.06) pileup not seen among multigiant systems. We find that the median mass (
M
sin
i
) of giants in multiples is nearly double that of single giants (1.71
M
J
versus 0.92
M
J
). We find that giant planets in the same system have correlated masses, analogous to the “peas in a pod” effect seen among less-massive planets.
Video filmed by a camera mounted on the head of a Northern Goshawk (Accipiter gentilis) was used to study how the raptor used visual guidance to pursue prey and land on perches. A combination of ...novel image analysis methods and numerical simulations of mathematical pursuit models was used to determine the goshawk's pursuit strategy. The goshawk flew to intercept targets by fixing the prey at a constant visual angle, using classical pursuit for stationary prey, lures or perches, and usually using constant absolute target direction (CATD) for moving prey. Visual fixation was better maintained along the horizontal than vertical direction. In some cases, we observed oscillations in the visual fix on the prey, suggesting that the goshawk used finite-feedback steering. Video filmed from the ground gave similar results. In most cases, it showed goshawks intercepting prey using a trajectory consistent with CATD, then turning rapidly to attack by classical pursuit; in a few cases, it showed them using curving non-CATD trajectories. Analysis of the prey's evasive tactics indicated that only sharp sideways turns caused the goshawk to lose visual fixation on the prey, supporting a sensory basis for the surprising frequency and effectiveness of this tactic found by previous studies. The dynamics of the prey's looming image also suggested that the goshawk used a tau-based interception strategy. We interpret these results in the context of a concise review of pursuit-evasion in biology, and conjecture that some prey deimatic 'startle' displays may exploit tau-based interception.
Abstract
We measured the Rossiter–McLaughlin effect of WASP-107b during a single transit with Keck/HIRES. We found the sky-projected inclination of WASP-107b’s orbit, relative to its host star’s ...rotation axis, to be
degrees. This confirms the misaligned/polar orbit that was previously suggested from spot-crossing events and adds WASP-107b to the growing population of hot Neptunes in polar orbits around cool stars. WASP-107b is also the fourth such planet to have a known distant planetary companion. We examined several dynamical pathways by which this companion could have induced such an obliquity in WASP-107b. We find that nodal precession and disk dispersal-driven tilting can both explain the current orbital geometry while Kozai–Lidov cycles are suppressed by general relativity. While each hypothesis requires a mutual inclination between the two planets, nodal precession requires a much larger angle, which for WASP-107 is on the threshold of detectability with future Gaia astrometric data. As nodal precession has no stellar type dependence, but disk dispersal-driven tilting does, distinguishing between these two models is best done on the population level. Finding and characterizing more extrasolar systems like WASP-107 will additionally help distinguish whether the distribution of hot-Neptune obliquities is a dichotomy of aligned and polar orbits or if we are uniformly sampling obliquities during nodal precession cycles.
We hypothesized that patients with oropharyngeal cancer treated with intensity modulated proton therapy (IMPT) would have lower symptom burdens, as measured by patient-reported outcome (PRO) surveys, ...than patients treated with intensity modulated photon therapy (IMRT).
Patients were treated for oropharyngeal cancer from 2006 to 2015 through prospective registries with concurrent chemotherapy and IMPT or chemotherapy and IMRT and completed the MD Anderson Symptom Inventory for Head and Neck Cancer (MDASI-HN) module at various times before treatment (baseline), during treatment (acute phase), within the first 3 months after treatment (subacute phase), and afterward (chronic phase). Individual symptoms and the top 5 and top 11 most severe symptoms were summarized and compared between the radiation therapy modalities.
PRO data were collected and analyzed from 35 patients treated with chemotherapy and IMPT and from 46 treated with chemotherapy and IMRT. The baseline symptom burdens were similar between both groups. The overall top 5 symptoms were food taste problems (mean score 4.91 on a 0-10 scale), dry mouth (4.49), swallowing/chewing difficulties (4.26), lack of appetite (4.08), and fatigue (4.00). Among the top 11 symptoms, changes in taste and appetite during the subacute and chronic phases favored IMPT (all P<.048). No differences in symptom burden were detected between modalities during the acute and chronic phases by top-11 symptom scoring. During the subacute phase, the mean (±standard deviation) top 5 MDASI scores were 5.15 ± 2.66 for IMPT versus 6.58 ± 1.98 for IMRT (P=.013).
According to the MDASI-HN, symptom burden was lower among the IMPT patients than among the IMRT patients during the subacute recovery phase after treatment. A prospective randomized clinical trial is underway to define the value of IMPT for the management of head and neck tumors.
Abstract
The detection of satellites around extrasolar planets, so called exomoons, remains a largely unexplored territory. In this work, we study the potential of detecting these elusive objects ...from radial velocity monitoring of self-luminous, directly imaged planets. This technique is now possible thanks to the development of dedicated instruments combining the power of high-resolution spectroscopy and high-contrast imaging. First, we demonstrate a sensitivity to satellites with a mass ratio of 1%–4% at separations similar to the Galilean moons from observations of a brown-dwarf companion (HR 7672 B;
K
mag
= 13; 0.″7 separation) with the Keck Planet Imager and Characterizer (
R
∼ 35,000 in the
K
band) at the W. M. Keck Observatory. Current instrumentation is therefore already sensitive to large unresolved satellites that could be forming from gravitational instability akin to binary star formation. Using end-to-end simulations, we then estimate that future instruments such as the Multi-Object Diffraction-limited High-resolution Infrared Spectrograph, planned for the Thirty Meter Telescope, should be sensitive to satellites with mass ratios of ∼10
−4
. Such small moons would likely form in a circumplanetary disk similar to the Jovian satellites in the solar system. Looking for the Rossiter–McLaughlin effect could also be an interesting pathway to detecting the smallest moons on short orbital periods. Future exomoon discoveries will allow precise mass measurements of the substellar companions that they orbit and provide key insight into the formation of exoplanets. They would also help constrain the population of habitable Earth-sized moons orbiting gas giants in the habitable zone of their stars.
Abstract
The Kepler and TESS missions have demonstrated that planets are ubiquitous. However, the success of these missions heavily depends on ground-based radial velocity (RV) surveys, which ...combined with transit photometry can yield bulk densities and orbital properties. While most Kepler host stars are too faint for detailed follow-up observations, TESS is detecting planets orbiting nearby bright stars that are more amenable to RV characterization. Here, we introduce the TESS-Keck Survey (TKS), an RV program using ∼100 nights on Keck/HIRES to study exoplanets identified by TESS. The primary survey aims are investigating the link between stellar properties and the compositions of small planets; studying how the diversity of system architectures depends on dynamical configurations or planet multiplicity; identifying prime candidates for atmospheric studies with JWST; and understanding the role of stellar evolution in shaping planetary systems. We present a fully automated target selection algorithm, which yielded 103 planets in 86 systems for the final TKS sample. Most TKS hosts are inactive, solar-like, main-sequence stars (4500 K ≤
T
eff
<6000 K) at a wide range of metallicities. The selected TKS sample contains 71 small planets (
R
p
≤ 4
R
⊕
), 11 systems with multiple transiting candidates, six sub-day-period planets and three planets that are in or near the habitable zone (
S
inc
≤ 10
S
⊕
) of their host star. The target selection described here will facilitate the comparison of measured planet masses, densities, and eccentricities to predictions from planet population models. Our target selection software is publicly available and can be adapted for any survey that requires a balance of multiple science interests within a given telescope allocation.